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CAS 959746-77-1

:

[N(Z)]-N-[3-(2-Methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethylcyclopropanecarboxamide

Description:
The chemical substance with the name "[N(Z)]-N-[3-(2-Methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethylcyclopropanecarboxamide" and CAS number "959746-77-1" is characterized by its complex molecular structure, which includes a thiazole ring, a cyclopropanecarboxamide moiety, and a methoxyethyl substituent. This compound likely exhibits unique properties due to the presence of multiple functional groups, which can influence its reactivity, solubility, and potential biological activity. The thiazole ring is known for its role in various biological systems and can contribute to the compound's pharmacological properties. The bulky tetramethylcyclopropane structure may enhance steric hindrance, potentially affecting the compound's interactions with biological targets. Additionally, the methoxyethyl group can enhance solubility in organic solvents, making it suitable for various applications in medicinal chemistry and material science. Overall, this compound's intricate structure suggests potential utility in drug development or as a research tool in chemical biology.
Formula:C16H26N2O2S
InChI:InChI=1S/C16H26N2O2S/c1-10-11(2)21-14(18(10)8-9-20-7)17-13(19)12-15(3,4)16(12,5)6/h12H,8-9H2,1-7H3/b17-14-
InChI key:InChIKey=JKGIMVBQKSRTGX-VKAVYKQESA-N
SMILES:C(/N=C\1/N(CCOC)C(C)=C(C)S1)(=O)C2C(C)(C)C2(C)C
Synonyms:
  • A-836,339
  • Cyclopropanecarboxamide, N-[3-(2-methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethyl-, [N(Z)]-
  • [N(Z)]-N-[3-(2-Methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethylcyclopropanecarboxamide
  • A-836339,A 836339,Cannabinoid Receptor,A836339,inhibit,Inhibitor
  • 1-(tetrahydropyran-4-ylMethyl)-1H-indol-3-yl]-(2,2,3,5-tetraMethylcyclopropyl)Methanone
  • (A836339)
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Found 3 products.
  • A-836339
    Targetmol
    + Info

    A-836339

    CAS:
    A-836339: Potent cannabinoid, CB2-focused (Ki=0.64nM), lesser CB1 affinity (Ki=270nM); analgesic, anti-inflammatory in mice.
    Formula:C16H26N2O2S
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:310.45

    Ref: TM-T7375

    2mg
    34.00€
    5mg
    67.00€
    10mg
    109.00€
    25mg
    177.00€
    50mg
    260.00€
    100mg
    369.00€
    200mg
    500.00€
    1mL*10mM (DMSO)
    63.00€
  • A-836339
    TRC
    + Info

    A-836339

    Controlled Product
    CAS:

    Applications A-836339, is a cannabinoid CB2 receptor-selective agonist; exhibits high potencies at CB(2) and selectivity over CB(1) receptors. Synthetic Cannabinoids.
    References Yao BB, et al. J Pharmacol Exp Ther. 2009 Jan;328(1):141-51. doi: 10.1124/jpet.108.145011. Epub 2008 Oct 17.

    Formula:C16H26N2O2S
    Color and Shape:Neat
    Molecular weight:310.455

    Ref: TR-A101255

    100mg
    2,087.00€
  • A-836,339
    Biosynth
    + Info

    A-836,339

    Controlled Product
    CAS:

    A-836,339 is a synthetic cannabinoid that has a high affinity for the CB1 and CB2 receptors. A-836,339 exhibits a profile of activities in functional assays similar to other synthetic cannabinoids and also has an affinity for the CB2 receptor. It was shown to inhibit TNF-α induced secretion of IL-6 from cultured human monocytes in vitro and to reduce nerve injury-induced spontaneous activity in rats. The effects are mediated by cannabinoid type 1 (CB1) receptors. A-836,339 also inhibited uptake of [3H]anandamide into synaptosomal preparations from rat brain tissue with IC50 values of 0.5 μM.

    Purity:Min. 95%

    Ref: 3D-CA175183

    ne
    Discontinued
    Discontinued product