CAS 959746-77-1

[N(Z)]-N-[3-(2-Methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethylcyclopropanecarboxamide

Description:

The chemical substance with the name "[N(Z)]-N-[3-(2-Methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethylcyclopropanecarboxamide" and CAS number "959746-77-1" is characterized by its complex molecular structure, which includes a thiazole ring, a cyclopropanecarboxamide moiety, and a methoxyethyl substituent. This compound likely exhibits unique properties due to the presence of multiple functional groups, which can influence its reactivity, solubility, and potential biological activity. The thiazole ring is known for its role in various biological systems and can contribute to the compound's pharmacological properties. The bulky tetramethylcyclopropane structure may enhance steric hindrance, potentially affecting the compound's interactions with biological targets. Additionally, the methoxyethyl group can enhance solubility in organic solvents, making it suitable for various applications in medicinal chemistry and material science. Overall, this compound's intricate structure suggests potential utility in drug development or as a research tool in chemical biology.

Formula: C₁₆H₂₆N₂O₂S

InChI: InChI=1S/C16H26N2O2S/c1-10-11(2)21-14(18(10)8-9-20-7)17-13(19)12-15(3,4)16(12,5)6/h12H,8-9H2,1-7H3/b17-14-

InChI key: InChIKey=JKGIMVBQKSRTGX-VKAVYKQESA-N

SMILES: C(/N=C\1/N(CCOC)C(C)=C(C)S1)(=O)C2C(C)(C)C2(C)C

Synonyms:

• A-836,339
• Cyclopropanecarboxamide, N-[3-(2-methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethyl-, [N(Z)]-
• [N(Z)]-N-[3-(2-Methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethylcyclopropanecarboxamide
• A-836339,A 836339,Cannabinoid Receptor,A836339,inhibit,Inhibitor
• 1-(tetrahydropyran-4-ylMethyl)-1H-indol-3-yl]-(2,2,3,5-tetraMethylcyclopropyl)Methanone
• (A836339)

A-836339

CAS: 959746-77-1

A-836339: Potent cannabinoid, CB2-focused (Ki=0.64nM), lesser CB1 affinity (Ki=270nM); analgesic, anti-inflammatory in mice.

Formula: C₁₆H₂₆N₂O₂S

Purity: 99.94%

Color and Shape: Solid

Molecular weight: 310.45

Ref: TM-T7375

A-836339

Controlled Product

CAS: 959746-77-1

Applications A-836339, is a cannabinoid CB2 receptor-selective agonist; exhibits high potencies at CB(2) and selectivity over CB(1) receptors. Synthetic Cannabinoids.
References Yao BB, et al. J Pharmacol Exp Ther. 2009 Jan;328(1):141-51. doi: 10.1124/jpet.108.145011. Epub 2008 Oct 17.

Formula: C₁₆H₂₆N₂O₂S

Color and Shape: Neat

Molecular weight: 310.455

Ref: TR-A101255