CAS 96203-70-2

(+)-Pancratistatin

Formula: C₁₄H₁₅NO₈

InChI: InChI=1S/C14H15NO8/c16-8-5-3-1-4-13(23-2-22-4)9(17)6(3)14(21)15-7(5)10(18)12(20)11(8)19/h1,5,7-8,10-12,16-20H,2H2,(H,15,21)/t5-,7-,8-,10+,11+,12+/m1/s1

InChI key: InChIKey=VREZDOWOLGNDPW-ALTGWBOUSA-N

SMILES: O[C@@H]1[C@@]2(C=3C(=C(O)C4=C(C3)OCO4)C(=O)N[C@]2([C@H](O)[C@H](O)[C@H]1O)[H])[H]

Synonyms:

• (+)-Pancratistatin
• (1R,2S,3S,4S,4aR,11bR)-1,3,4,4a,5,11b-Hexahydro-1,2,3,4,7-pentahydroxy[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one
• NSC 349156
• Pancratistatine
• [1,3]Dioxolo[4,5-j]phenanthridin-6(2H)-one, 1,3,4,4a,5,11b-hexahydro-1,2,3,4,7-pentahydroxy-, [1R-(1α,2β,3α,4α,4aα,11bβ)]-
• [1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one, 1,3,4,4a,5,11b-hexahydro-1,2,3,4,7-pentahydroxy-, (1R,2S,3S,4S,4aR,11bR)-
• [1,3]dioxolo[4,5-j]phenanthridine-1,2,3,4,6,7-hexol, 1,2,3,4,4a,11b-hexahydro-, (1R,2S,3S,4S,4aR,11bR)-

Pancratistatin

CAS: 96203-70-2

Pancratistatin

Formula: C₁₄H₁₅NO₈

Purity: ≥98%

Molecular weight: 325.27

Ref: 54-OR1130102

Pancratistatin

CAS: 96203-70-2

Pancratistatin, an isoquinoline from Hymenocallis littoralis, triggers apoptosis in melanoma and is studied for neuroblastoma, leukemia, and breast cancer.

Formula: C₁₄H₁₅NO₈

Color and Shape: Solid

Molecular weight: 325.27

Ref: TM-T73640

Pancratistatin

Controlled Product

CAS: 96203-70-2

Stability Hygroscopic
Applications Pancratistatin acts as an anti-cancer compound that initiates cell-death in cancer cells.
References McLachlan, A. et al.: Apoptosis, 10, 619 (2005);

Formula: C₁₄H₁₅NO₈

Color and Shape: Neat

Molecular weight: 325.27

Ref: TR-P173600

Pancratistatin

CAS: 96203-70-2

Pancratistatin is a naturally-derived alkaloid, primarily isolated from the bulbs of the Pancratium littorale and other members of the Amaryllidaceae family. It exerts its biological activity through the selective induction of apoptosis in cancer cells while sparing normal cells. This remarkable selectivity is likely due to the compound’s ability to target mitochondrial pathways, disrupting the cancer cell's energy metabolism and triggering cell death without affecting healthy tissue.

Formula: C₁₄H₁₅NO₈

Purity: Min. 95%

Molecular weight: 325.27 g/mol

Ref: 3D-WDA20370