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CAS 96206-92-7

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MPEP

Description:
MPEP, or 2-Methyl-6-(phenylethynyl)pyridine, is a chemical compound recognized for its role as a selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It is often studied in the context of neurological research, particularly for its potential implications in treating conditions such as anxiety, depression, and other neuropsychiatric disorders. MPEP is characterized by its pyridine ring structure, which is substituted with a phenylethynyl group and a methyl group, contributing to its pharmacological properties. The compound is typically found in a solid state and is soluble in organic solvents. Its mechanism of action involves modulating glutamate signaling, which is crucial for synaptic plasticity and cognitive functions. Due to its specificity for mGluR5, MPEP serves as a valuable tool in pharmacological studies aimed at understanding glutamate-related pathways in the brain. As with many research chemicals, safety and handling precautions are essential when working with MPEP in laboratory settings.
Formula:C14H11N
InChI:InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3
InChI key:InChIKey=NEWKHUASLBMWRE-UHFFFAOYSA-N
SMILES:C(#CC1=CC=CC=C1)C=2N=C(C)C=CC2
Synonyms:
  • 2-Methyl-6-(2-phenylethynyl)pyridine
  • 2-Methyl-6-(phenylethynyl)pyridine
  • 2-Picoline, 6-phenylethynyl-
  • Pyridine, 2-methyl-6-(2-phenylethynyl)-
  • Pyridine, 2-methyl-6-(2-phenylethynyl)-, hydrochloride (1:1)
  • Pyridine, 2-methyl-6-(phenylethynyl)-
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