CAS 96574-01-5

Salvianolic acid

Description:

Salvianolic acid, with the CAS number 96574-01-5, is a water-soluble polyphenolic compound primarily derived from the roots of Salvia miltiorrhiza, commonly known as Danshen. This compound is known for its potent antioxidant properties, which help in scavenging free radicals and reducing oxidative stress. Salvianolic acid exhibits various pharmacological effects, including anti-inflammatory, cardioprotective, and neuroprotective activities, making it of interest in the field of medicinal chemistry. Its structure features multiple hydroxyl groups, contributing to its high reactivity and biological activity. Additionally, salvianolic acid has been studied for its potential role in improving blood circulation and protecting against cardiovascular diseases. The compound is often explored in traditional medicine and modern therapeutic applications, highlighting its significance in both historical and contemporary health practices. Its solubility in water enhances its bioavailability, making it a suitable candidate for various formulations in herbal medicine and dietary supplements.

Formula: C₂₆H₂₂O₁₀

InChI: InChI=1S/C26H22O10/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15/h1-12,23,27-31,33H,13H2,(H,34,35)/b6-1+,10-5+/t23-/m1/s1

InChI key: InChIKey=YMGFTDKNIWPMGF-UCPJVGPRSA-N

SMILES: C(=C/C1=CC(O)=C(O)C=C1)\C2=C(/C=C/C(O[C@H](CC3=CC(O)=C(O)C=C3)C(O)=O)=O)C=CC(O)=C2O

Synonyms:

• (2R)-3-(3,4-Dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoyl]oxypropanoic acid
• (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-{2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl}prop-2-enoyl]oxy}propanoic acid
• (αR)-α-[[(2E)-3-[2-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxybenzenepropanoic acid
• 3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-{2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl}prop-2-enoyl]oxy}propanoic acid
• Benzenepropanoic acid, α-[[(2E)-3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-, (αR)-
• Benzenepropanoic acid, α-[[(2E)-3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-, (αR)-
• Benzenepropanoic acid, α-[[3-[2-[2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-, [R-(E,E)]-
• Dan phenolic acid A
• Salvianolic acid
• (+)-Salvianolic acid A

(R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid

CAS: 96574-01-5

Formula: C₂₆H₂₂O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 494.4469

Ref: IN-DA0039H9

Salvianolic acid A hydrate

CAS: 96574-01-5

Formula: C₂₆H₂₂O₁₀·xH₂O

Purity: ≥ 98.0%

Color and Shape: Yellow powder

Molecular weight: 494.45 (anhydrous)

Ref: 7W-GL2576

Salvianolic acid A

CAS: 96574-01-5

Salvianolic acid A

Formula: C₂₆H₂₂O₁₀

Purity: ≥98%

Molecular weight: 494.45

Ref: 54-BUP13382

Salvianolic acid A

CAS: 96574-01-5

Salvianolic acid A has antioxidant, hepatoprotective, antithrombotic effect, and antiplatelet actions. it also has a significant protective effect against isoproterenol-induced myocardial infarction; it activates the Nrf2/HO-1 axis in RPE cells and protects against oxidative stress via activation of Akt/mTORC1 signaling. Salvianolic acid A (oral) can significantly improve glucose metabolism and inhibit oxidative injury as well as protect against impaired vascular responsiveness in STZ-induced diabetic rats. It is a novel matrix metalloproteinase-9 inhibitor, can prevents cardiac remodeling in spontaneously hypertensive rats.

Formula: C₂₆H₂₂O₁₀

Purity: 95%~99%

Molecular weight: 494.452

Ref: BP-BP1247

Salvianolic acid A

CAS: 96574-01-5

Salvianolic acid A (Dan Phenolic Acid A) is an MMP-9 inhibitor. Salvianolic acid A has anti-inflammatory activity. Cost-effective and quality-assured.

Formula: C₂₆H₂₂O₁₀

Purity: 99.08% - >99.99%

Color and Shape: Yellow Solid

Molecular weight: 494.45

Ref: TM-T6S0444

Salvianolic acid A

CAS: 96574-01-5

Carboxylic acid with phenol function

Formula: C₂₆H₂₂O₁₀

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 494.46

Ref: 5G-80530

Salvianolic acid A

CAS: 96574-01-5

Salvianolic acid A is a polyphenolic compound, which is derived from the roots of the plant Salvia miltiorrhiza, commonly known as Danshen. It exerts its effects primarily through its potent antioxidant and anti-inflammatory activities. This compound operates by scavenging free radicals and inhibiting pro-inflammatory mediators, thus providing protection against oxidative stress and inflammation-related damage.

Formula: C₂₆H₂₂O₁₀

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 494.45 g/mol

Ref: 3D-FS73769

Salvianolic acid A

CAS: 96574-01-5

(R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid

Formula: C₂₆H₂₂O₁₀

Purity: 98%

Molecular weight: 494.45

Ref: IN-DG44561

SALVIANOLIC ACID A

CAS: 96574-01-5

Purity: 98%

Molecular weight: 494.4519958

Ref: 10-F859167

Salvianolic Acid A

Controlled Product

CAS: 96574-01-5

Applications ISalvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL.
References Lin, T., et al.: Biochem. Pharmacol., 51, 1237 (1996), Abd-Elazem, I., et al.: Antivir. Res., 55, 91 (2002), Ji, X., et al.: Life Sci., 73, 1413 (2003), Lin, Y., et al.: Biochem. Biophys. Res. Commun., 348, 593 (2006),

Formula: C₂₆H₂₂O₁₀

Color and Shape: Neat

Molecular weight: 494.45

Ref: TR-S100800