CAS 96680-30-7

1-[[(1-Methylethoxy)carbonyl]oxy]ethyl (6R,7R)-7-[[(2Z)-2-[2-(formylamino)-4-thiazolyl]-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Description:

The chemical substance known as 1-[[(1-Methylethoxy)carbonyl]oxy]ethyl (6R,7R)-7-[[(2Z)-2-[2-(formylamino)-4-thiazolyl]-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, with the CAS number 96680-30-7, is a complex organic compound characterized by its bicyclic structure and multiple functional groups. It features a thiazole ring, which is known for its biological activity, particularly in pharmaceuticals. The presence of methoxy and formylamino groups suggests potential reactivity and interactions in biological systems. This compound is likely to exhibit properties such as solubility in organic solvents, stability under specific conditions, and potential antimicrobial or therapeutic effects, given its structural components. Its intricate arrangement of atoms and functional groups may contribute to its specificity in biological applications, making it a subject of interest in medicinal chemistry and drug development. Further studies would be necessary to fully elucidate its properties and potential uses.

Formula: C₂₂H₂₇N₅O₁₀S₂

InChI: InChI=1S/C22H27N5O10S2/c1-10(2)35-22(32)37-11(3)36-20(31)16-12(6-33-4)7-38-19-15(18(30)27(16)19)25-17(29)14(26-34-5)13-8-39-21(24-13)23-9-28/h8-11,15,19H,6-7H2,1-5H3,(H,25,29)(H,23,24,28)/b26-14-/t11?,15-,19-/m1/s1

InChI key: InChIKey=KBBPBOYVHDSXFI-KMMUMHRISA-N

SMILES: C(OC(OC(OC(C)C)=O)C)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(NC=O)SC3)=O)C2=O)(SCC1COC)[H]

Synonyms:

• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-[2-(formylamino)-4-thiazolyl](methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, (6R,7R)-
• 1-[[(1-Methylethoxy)carbonyl]oxy]ethyl (6R,7R)-7-[[(2Z)-2-[2-(formylamino)-4-thiazolyl]-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[2-(formylamino)-4-thiazolyl](methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-[2-(formylamino)-4-thiazolyl]-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, (6R,7R)-

N-Formyl Cefpodoxime Proxetil (1-[(Isopropoxycarbonyl)oxy]ethyl (6R,7R)-7-[(Z)-2-(2-formamidothiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate)

CAS: 96680-30-7

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure

Formula: C₂₂H₂₇N₅O₁₀S₂

Molecular weight: 585.11993

Ref: 45-1A18680

Cefpodoxime Proxetil EP Impurity F (Mixture of Diastereomers)

CAS: 96680-30-7

Formula: C₂₂H₂₇N₅O₁₀S₂

Color and Shape: White To Off-White Solid

Molecular weight: 585.60

Ref: 4Z-C-857

2-Formyl-cefpodoxime Proxetil

Controlled Product

CAS: 96680-30-7

Impurity Cefpodoxime Proxetil EP Impurity F
Applications 2-Formyl-cefpodoxime Proxetil (Cefpodoxime Proxetil EP Impurity F) is a useful intermediate to prepare cefpodoxime proxetil (C243860), a cephalosporin antibiotic used to treat bacterial infections.
References Fujimoto, K., et al.: J. Antibiot., 40, 370 (1987); Utsui, Y., et al.: Antimicrob. Agents Chemother., 31, 1085 (1987)

Formula: C₂₂H₂₇N₅O₁₀S₂

Color and Shape: Neat

Molecular weight: 585.61

Ref: TR-F698700

2-Formyl-cefpodoxime proxetil

CAS: 96680-30-7

2-Formyl-cefpodoxime proxetil is a protein inhibitor that has shown promising results in the treatment of tumors and cancer. This drug works by inhibiting kinases, which are enzymes that play a crucial role in cell division and growth. 2-Formyl-cefpodoxime proxetil has been shown to induce apoptosis, or programmed cell death, in cancer cells. This makes it an effective anticancer agent with potential for use in chemotherapy treatments. Chinese analogs of this drug have also been found in urine samples from cancer patients, further highlighting its potential as a cancer therapy. In addition to its anticancer properties, 2-Formyl-cefpodoxime proxetil has also been studied as a toxin inhibitor and may have applications beyond the realm of cancer treatment.

Formula: C₂₂H₂₇N₅O₁₀S₂

Purity: Min. 95%

Molecular weight: 585.6 g/mol

Ref: 3D-WDA68030

Cefpodoxime Proxetil EP Impurity F

CAS: 96680-30-7

Formula: C₂₂H₂₇N₅O₁₀S₂

Molecular weight: 585.6

Ref: ST-EA-CP-C156006