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CAS 967-80-6

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Sulfaquinoxaline sodium

Description:
Sulfaquinoxaline sodium is a sulfonamide antibiotic primarily used in veterinary medicine, particularly for the treatment of coccidiosis in poultry and other livestock. It is a sodium salt of sulfaquinoxaline, which is a synthetic derivative of sulfanilamide. The compound exhibits broad-spectrum antimicrobial activity by inhibiting bacterial dihydropteroate synthase, an enzyme critical for folate synthesis, thereby disrupting nucleic acid synthesis in bacteria. Sulfaquinoxaline sodium is typically administered orally or through feed and is known for its relatively low toxicity in animals when used at recommended dosages. It is soluble in water, which facilitates its incorporation into animal feed. However, its use is regulated in food-producing animals due to potential residues in meat and eggs, necessitating adherence to withdrawal times before slaughter. Additionally, resistance development in pathogens is a concern, prompting careful management of its use in veterinary practices. Overall, sulfaquinoxaline sodium plays a significant role in animal health, particularly in the prevention and treatment of infectious diseases.
Formula:C14H11N4NaO2S
InChI:InChI=1/C14H11N4O2S.Na/c15-10-1-4-12(5-2-10)21(19,20)18-11-3-6-13-14(9-11)17-8-7-16-13;/h1-9H,15H2;/q-1;+1
InChI key:InChIKey=UBDSWJJGFQSVLE-UHFFFAOYSA-N
SMILES:N(S(=O)(=O)C1=CC=C(N)C=C1)C2=NC3=C(N=C2)C=CC=C3.[Na]
Synonyms:
  • Benzenesulfonamide, 4-amino-N-2-quinoxalinyl-, monosodium salt
  • Benzenesulfonamide, 4-amino-N-2-quinoxalinyl-, sodium salt (1:1)
  • Embazin
  • N'1-Quinoxalin-2-ylsulphanilamide sodium salt
  • Noxal
  • Noxal (antimicrobial)
  • Sodium 2-sulfanilamidoquinoxaline
  • Sodium [(4-Aminophenyl)Sulfonyl](Quinoxalin-6-Yl)Azanide
  • Sodium sulfaquinoxaline
  • Sodium, (N<sup>1</sup>-2-quinoxalinylsulfanilamido)-
  • See more synonyms
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