CAS 96964-90-8

2-amino-8-benzyloxy-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-purin-6-one

Description:

2-amino-8-benzyloxy-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-purin-6-one, with CAS number 96964-90-8, is a purine derivative characterized by its complex structure that includes an amino group, a benzyloxy substituent, and a tetrahydrofuran moiety. This compound features a bicyclic purine core, which is essential for biological activity, particularly in nucleic acid chemistry. The presence of the hydroxymethyl group and the tetrahydrofuran ring contributes to its solubility and potential interactions with biological targets. Its structural features suggest that it may exhibit properties relevant to medicinal chemistry, possibly acting as an inhibitor or modulator in biochemical pathways. The compound's stereochemistry, indicated by the (2R,5R) configuration, is crucial for its biological activity, influencing how it interacts with enzymes or receptors. Overall, this compound represents a class of molecules that may have applications in drug development, particularly in the fields of antiviral or anticancer therapies.

Formula: C₁₇H₁₉N₅O₅

InChI: InChI=1/C17H19N5O5/c18-16-20-14-13(15(25)21-16)19-17(26-8-9-4-2-1-3-5-9)22(14)12-6-10(24)11(7-23)27-12/h1-5,10-12,23-24H,6-8H2,(H3,18,20,21,25)/t10?,11-,12-/m1/s1

InChI key: AMEUNRVTNJBDJN-QJPTWQEYSA-N

SMILES: c1ccc(cc1)COc1nc2c([nH]c(=N)nc2O)n1[C@H]1CC([C@@H](CO)O1)O

8-Benzyloxy-2'-deoxyguanosine

CAS: 96964-90-8

8-Benzyloxy-2'-deoxyguanosine

Formula: C₁₇H₁₉N₅O₅

Purity: 95%

Molecular weight: 373.36

Ref: 54-OR1113586

8-Benzyloxy-2''-deoxyguanosine

CAS: 96964-90-8

Ref: 7W-GN0704

8-Benzyloxy-2'-deoxyguanosine

CAS: 96964-90-8

8-Benzyloxy-2'-deoxyguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

Formula: C₁₇H₁₉N₅O₅

Color and Shape: Solid

Molecular weight: 373.36

Ref: TM-TNU0931

8-Benzyloxy-2’-deoxyguanosine

CAS: 96964-90-8

Formula: C₁₇H₁₉N₅O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 373.3633

Ref: IN-DA0065P9

8-Benzyloxy-2’-deoxyguanosine

Controlled Product

CAS: 96964-90-8

Applications 8-Benzyloxy-2’-deoxyguanosine (cas# 96964-90-8) is a compound useful in organic synthesis.
References Wang, Y., et al.: Chem. Res. Toxicol., 19, 837 (2006),

Formula: C₁₇H₁₉N₅O₅

Color and Shape: Neat

Molecular weight: 373.36

Ref: TR-B285935

8-Benzyloxy-2'-deoxyguanosine

CAS: 96964-90-8

8-Benzyloxy-2'-deoxyguanosine is a dinucleoside that is synthesised from uracil and hydrogenated 8-hydroxyquinoline. The synthesis of 8-benzyloxy-2'-deoxyguanosine was achieved by cyclic photocyclization of 2,4,6-trichlorobenzaldehyde with 2,4,6-trimethoxyphenylacetone in the presence of sodium nitrite. This compound has been used for the quantification of DNA damage caused by irradiation or sodium chloride. 8-Benzyloxy-2'-deoxyguanosine has also been shown to inhibit the polymerase chain reaction (PCR) amplification of oligodeoxynucleotides.

Formula: C₁₇H₁₉N₅O₅

Purity: Min. 95%

Color and Shape: Off-White To Brown Solid

Molecular weight: 373.36 g/mol

Ref: 3D-NB06296