CAS 96989-76-3

Acebrophylline

Description:

Acebrophylline is a mucolytic agent primarily used in the treatment of respiratory conditions characterized by excessive mucus production, such as chronic bronchitis and asthma. It is a derivative of theophylline and possesses both mucolytic and anti-inflammatory properties, which help in thinning and loosening mucus in the airways, facilitating easier expectoration. The substance is typically administered orally and is known for its relatively good tolerability profile. Acebrophylline works by breaking down the structure of mucus, making it less viscous, and enhancing ciliary function in the respiratory tract. Additionally, it may exhibit antioxidant effects, contributing to its therapeutic benefits. The compound is often formulated in combination with other medications to enhance its efficacy in managing respiratory disorders. As with any medication, potential side effects may include gastrointestinal disturbances or allergic reactions, although these are generally rare. Overall, acebrophylline is recognized for its role in improving respiratory function and quality of life for patients with chronic respiratory diseases.

Formula: C₂₂H₂₈Br₂N₆O₅

InChI: InChI=1/C13H18Br2N2O.C9H10N4O4/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h5-6,10-11,17-18H,1-4,7,16H2;4H,3H2,1-2H3,(H,14,15)

SMILES: C1CC(CCC1NCc1cc(cc(c1N)Br)Br)O.Cn1c2c(c(=O)n(C)c1=O)n(CC(=O)O)cn2

Synonyms:

• Cyclohexanol, 4-(((2-amino-3,5-dibromophenyl)methyl)amino)-, trans-,mono(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purine-7-acetate) (salt)
• (1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid - 4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol (1:1)

Acebrophylline

CAS: 96989-76-3

Formula: C₂₂H₂₈Br₂N₆O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 616.3029199999999

Ref: IN-DA0065P4

Acebrophylline

CAS: 96989-76-3

Formula: C₁₃H₁₈Br₂N₂O·C₉H₁₀N₄O₄

Molecular weight: 378.11 238.20

Ref: 4Z-A-6042

Acebrophylline

CAS: 96989-76-3

Formula: C₁₃H₁₈Br₂N₂O·C₉H₁₀N₄O₄

Molecular weight: 616.3

Ref: TR-A123700

Acebrophylline

Controlled Product

CAS: 96989-76-3

Acebrophylline is an antiinflammatory drug that inhibits the activity of phosphodiesterase and cyclooxygenase. It has been shown to be effective against chronic bronchitis and inflammatory bowel diseases. Acebrophylline is a prodrug that is metabolized by the liver to its active form, 3-hydroxyacebrophylline. This prodrug has a covalent linkage with the anti-inflammatory agent propranolol hydrochloride and can be administered orally or intravenously. The drug's efficacy in inflammatory bowel disease may be due to its ability to inhibit prostaglandin synthesis.

Formula: C₂₂H₂₈Br₂N₆O₅

Purity: Min. 97 Area-%

Color and Shape: Clear Liquid

Molecular weight: 616.3 g/mol

Ref: 3D-FA32125