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CAS 96989-76-3

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Acebrophylline

Description:
Acebrophylline is a mucolytic agent primarily used in the treatment of respiratory conditions characterized by excessive mucus production, such as chronic bronchitis and asthma. It is a derivative of theophylline and possesses both mucolytic and anti-inflammatory properties, which help in thinning and loosening mucus in the airways, facilitating easier expectoration. The substance is typically administered orally and is known for its relatively good tolerability profile. Acebrophylline works by breaking down the structure of mucus, making it less viscous, and enhancing ciliary function in the respiratory tract. Additionally, it may exhibit antioxidant effects, contributing to its therapeutic benefits. The compound is often formulated in combination with other medications to enhance its efficacy in managing respiratory disorders. As with any medication, potential side effects may include gastrointestinal disturbances or allergic reactions, although these are generally rare. Overall, acebrophylline is recognized for its role in improving respiratory function and quality of life for patients with chronic respiratory diseases.
Formula:C22H28Br2N6O5
InChI:InChI=1/C13H18Br2N2O.C9H10N4O4/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h5-6,10-11,17-18H,1-4,7,16H2;4H,3H2,1-2H3,(H,14,15)
SMILES:C1CC(CCC1NCc1cc(cc(c1N)Br)Br)O.Cn1c2c(c(=O)n(C)c1=O)n(CC(=O)O)cn2
Synonyms:
  • Cyclohexanol, 4-(((2-amino-3,5-dibromophenyl)methyl)amino)-, trans-,mono(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purine-7-acetate) (salt)
  • (1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid - 4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol (1:1)
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