CAS 97240-79-4
:Topiramate
Description:
Topiramate is a sulfamate-substituted monosaccharide that is primarily used as an anticonvulsant and for the prevention of migraines. Its chemical formula is C12H21N3O8S, and it features a unique structure that includes a sulfamate group, which contributes to its pharmacological properties. Topiramate is known for its ability to inhibit certain neurotransmitter pathways, particularly those involving glutamate, and it enhances the activity of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. This dual mechanism of action makes it effective in controlling seizures and preventing migraine attacks. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Topiramate is also associated with a range of side effects, including cognitive impairment, weight loss, and potential metabolic acidosis. Its safety profile and efficacy have made it a widely prescribed medication in neurology and psychiatry. As with any medication, it is important for patients to discuss potential risks and benefits with their healthcare provider.
Formula:C12H21NO8S
InChI:InChI=1/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9?,12+/m0/s1
InChI key:InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N
SMILES:C(OS(N)(=O)=O)[C@]12[C@]([C@]3([C@@](CO1)(OC(C)(C)O3)[H])[H])(OC(C)(C)O2)[H]
Synonyms:- 2,3:4,5-Bis-O-(1-methylethylidene) β-<span class="text-smallcaps">D</span>-fructopyranose sulfamate
- 2,3:4,5-Bis-O-(1-methylethylidene) β-D-fructopyranose sulfamate
- 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
- 5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran, β-<span class="text-smallcaps">D</span>-fructopyranose deriv.
- Epitoma
- Epitomax
- McN 4853
- Qudexy XR
- Rwj 17021
- Sincronil
- TPM
- Toiramate
- Topamac
- Topamax
- Topimax
- Topina
- Topiragen
- Topomax
- Tracrium
- Trokendi XR
- β-<span class="text-smallcaps">D</span>-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
- β-<span class="text-smallcaps">D</span>-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
- β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
- β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
- Topiramate
- 5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran, β-D-fructopyranose deriv.
- 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulfamate
- Topiramato [INN-Spanish]
- 1-O-Sulfamoyl-2-O,3-O:4-O,5-O-diisopropylidene-β-D-fructopyranose
- Topiramate Synonyms Topamax
- TopiramateTopamax
- Topiramate solution
- 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranoside sulfamate
- 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranosidesulfamate
- Topiramate (150 mg)
- Tipiramato [Spanish]
- 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose sulfamate
- RWJ-17021-000
- TopiraMate(McN-4853,RWJ-17021,TopaMax)
- Tipiramate [French]
- Topiramic acid
- .beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
- McN 4853, RWJ 17021, Topamax, 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate
- 1-O-Sulfamoyl-2-O,3-O:4-O,5-O-bis(1-methylethylidene)-β-D-fructopyranose
- TopiraMate API
- 2,3:4,5-Bis-O-(1-methylethylidene)--D-fuctopyranose Sulfamate, McN-4853, RWJ-17021-000, Topamax
- ((3aS,5aR,8aR,8bS)-2,2,7,7-tetraMethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)Methyl sulfaMate
- ((3AS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl
- 2,3:4,5-Bis-O-(1-Methylethylidene)-β-D-fuctopyranose 1-SulfaMate
- Topiramatum [INN-Latin]
- TopiriMate-d12
- 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-B-D-FUCTO-PYRANOSE SULFAMATE
- Topiramate [USAN:BAN:INN]
- PHARMACEUTICAL RAW MATERIAL: TOPIRAMATEUSP
- topiramatum [Latin]
- 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranossulfamate
- 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-36-D-FRUCTO-PYRANOSE SULFAMATE
- 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamate
- 2,3:4,5-Di-O-isopropylidene-1-O-sulfamoyl-beta-D-fructopyranose
- Topiramate, >=98%
- 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-BETA-D-FUCTOPYRANOSE SULFAMATE
- See more synonyms
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Found 19 products.
Topiramate
CAS:Sulfonamides used as drugsFormula:C12H21NO8SColor and Shape:White Off-White Crystalline PowderMolecular weight:339.09879Topiramate
CAS:<p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:339.36Topiramate
CAS:Formula:C12H21NO8SPurity:98.0 - 102.0 % (anhydrous basis)Color and Shape:White to almost white powderMolecular weight:339.36Topiramate
CAS:Formula:C12H21NO8SPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:339.36Topiramate-13C6
CAS:Controlled Product<p>Applications Topiramate-13C6 is the labeled compound of Topiramate (T540250). Topiramate is used as an anticonvulsant.<br>References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987); Bialer, M.: Clin. Pharmacokinet., 24(6), 441-52 (1993)<br></p>Formula:C6C6H21NO8SColor and Shape:NeatMolecular weight:345.318Topiramate
CAS:<p>Applications Used as an anticonvulsant.<br>References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987); Bialer, M.: Clin. Pharmacokinet., 24(6), 441-52 (1993)<br></p>Formula:C12H21NO8SColor and Shape:White To Off-WhiteMolecular weight:339.36Topiramate
CAS:Controlled Product<p>An anticonvulsant drug</p>Formula:C12H21NO8SPurity:Min. 95%Color and Shape:PowderMolecular weight:339.37 g/molTopiramate - Bio-X ™
CAS:<p>Topiramate is an anticonvulsant drug that is used for the control of seizures and in the prophylaxis and treatment of migraines. This drug increases GABA activity and inhibits glutamate activity, therefore blocking neuronal excitability. This leads to a prevention in seizures and migraines.</p>Formula:C12H21NO8SPurity:Min. 95%Color and Shape:PowderMolecular weight:339.36 g/mol
