CAS 97240-79-4: Topiramate

Description:Topiramate is a sulfamate-substituted monosaccharide that is primarily used as an anticonvulsant and for the prevention of migraines. Its chemical formula is C12H21N3O8S, and it features a unique structure that includes a sulfamate group, which contributes to its pharmacological properties. Topiramate is known for its ability to inhibit certain neurotransmitter pathways, particularly those involving glutamate, and it enhances the activity of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. This dual mechanism of action makes it effective in controlling seizures and preventing migraine attacks. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Topiramate is also associated with a range of side effects, including cognitive impairment, weight loss, and potential metabolic acidosis. Its safety profile and efficacy have made it a widely prescribed medication in neurology and psychiatry. As with any medication, it is important for patients to discuss potential risks and benefits with their healthcare provider.

Formula:C₁₂H₂₁NO₈S

InChI:InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1

InChI key:InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N

SMILES:O=S(=O)(OCC12OCC3OC(OC3C2OC(O1)(C)C)(C)C)N

Synonyms:
2,3:4,5-Bis-O-(1-methylethylidene) β-D-fructopyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene) β-D-fructopyranose sulfamate
2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran, β-D-fructopyranose deriv.
Epitoma
Epitomax
McN 4853
Qudexy XR
Rwj 17021
Sincronil
See more synonyms
TPM
Toiramate
Topamac
Topamax
Topimax
Topina
Topiragen
Topomax
Tracrium
Trokendi XR
β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
Topiramate
5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran, β-D-fructopyranose deriv.
2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulfamate
Topiramato [INN-Spanish]
1-O-Sulfamoyl-2-O,3-O:4-O,5-O-diisopropylidene-β-D-fructopyranose
Topiramate Synonyms Topamax
TopiramateTopamax
Topiramate solution
2,3:4,5-Di-O-isopropylidene-β-D-fructopyranoside sulfamate
2,3:4,5-Di-O-isopropylidene-b-D-fructopyranosidesulfamate
Topiramate (150 mg)
Tipiramato [Spanish]
2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose sulfamate
RWJ-17021-000
TopiraMate(McN-4853,RWJ-17021,TopaMax)
Tipiramate [French]
Topiramic acid
.beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
McN 4853, RWJ 17021, Topamax, 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate
1-O-Sulfamoyl-2-O,3-O:4-O,5-O-bis(1-methylethylidene)-β-D-fructopyranose
TopiraMate API
2,3:4,5-Bis-O-(1-methylethylidene)--D-fuctopyranose Sulfamate, McN-4853, RWJ-17021-000, Topamax
((3aS,5aR,8aR,8bS)-2,2,7,7-tetraMethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)Methyl sulfaMate
((3AS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl
2,3:4,5-Bis-O-(1-Methylethylidene)-β-D-fuctopyranose 1-SulfaMate
Topiramatum [INN-Latin]
TopiriMate-d12
2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-B-D-FUCTO-PYRANOSE SULFAMATE
Topiramate [USAN:BAN:INN]
PHARMACEUTICAL RAW MATERIAL: TOPIRAMATEUSP
topiramatum [Latin]
2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranossulfamate
2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-36-D-FRUCTO-PYRANOSE SULFAMATE
2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamate
2,3:4,5-Di-O-isopropylidene-1-O-sulfamoyl-beta-D-fructopyranose
Topiramate, >=98%
2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-BETA-D-FUCTOPYRANOSE SULFAMATE
2,3:4,5-Bis-O-(1-methylethylidene)-b-D-fuctopyranose Sulfamate, McN-4853, RWJ-17021-000, Topamax

Found 16 products.

Product data	Purity	Price range	Estimated delivery
TOPIRAMATE CRS REF: 41-Y0002134CAS: 97240-79-4	- - -	115.00 €	Thu 31 Jul 25
Topiramate REF: 45-1672206CAS: 97240-79-4	- - -	615.00 €	Fri 01 Aug 25
Topiramate REF: IN-DA00IJX6CAS: 97240-79-4	98%	26.00 €~552.00 €	Mon 04 Aug 25
Topiramate REF: TM-T0675CAS: 97240-79-4	99.79% - 99.92%	46.00 €~156.00 €	Mon 04 Aug 25
Topiramate REF: 7W-GC1245CAS: 97240-79-4	98.0 - 102.0 % (anhydrous basis)	79.00 €~243.00 €	Tue 05 Aug 25
Topiramate REF: 54-OR1028318CAS: 97240-79-4	- - -	32.00 €~1,363.00 €	Tue 05 Aug 25
Topiramate REF: 4Z-T-0511CAS: 97240-79-4	- - -	To inquire	Tue 05 Aug 25
Topiramate REF: 54-BUP14122CAS: 97240-79-4	≥95%	61.00 €~437.00 €	Tue 05 Aug 25
Topiramate REF: 3B-T2755CAS: 97240-79-4	>98.0%(T)(HPLC)	54.00 €~181.00 €	Tue 05 Aug 25
Topiramate REF: 86-MM1348.00CAS: 97240-79-4	- - -	1,157.00 €	Tue 05 Aug 25
[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate REF: 10-F372976CAS: 97240-79-4	98.0%	To inquire	Tue 12 Aug 25
Topiramate-13C6 REF: TR-T540251CAS: 97240-79-4	- - -	348.00 €~2,206.00 €	Tue 12 Aug 25
Topiramate REF: TR-T540250CAS: 97240-79-4	- - -	106.00 €~1,170.00 €	Tue 12 Aug 25
Topiramate REF: 3D-MD03549CAS: 97240-79-4	Min. 95%	257.00 €~1,147.00 €	Wed 13 Aug 25
Topiramate - Bio-X ™ REF: 3D-BT167048CAS: 97240-79-4	Min. 95%	135.00 €	Wed 13 Aug 25
Topiramate, 98% REF: AC-45619CAS: 97240-79-4	98%	- - -	Discontinued product