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Topiramate

CAS 97240-79-4: Topiramate

Description:Topiramate is a sulfamate-substituted monosaccharide that is primarily used as an anticonvulsant and for the prevention of migraines. Its chemical formula is C12H21N3O8S, and it features a unique structure that includes a sulfamate group, which contributes to its pharmacological properties. Topiramate is known for its ability to inhibit certain neurotransmitter pathways, particularly those involving glutamate, and it enhances the activity of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. This dual mechanism of action makes it effective in controlling seizures and preventing migraine attacks. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Topiramate is also associated with a range of side effects, including cognitive impairment, weight loss, and potential metabolic acidosis. Its safety profile and efficacy have made it a widely prescribed medication in neurology and psychiatry. As with any medication, it is important for patients to discuss potential risks and benefits with their healthcare provider.

Formula:C12H21NO8S

InChI:InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1

InChI key:InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N

SMILES:O=S(=O)(OCC12OCC3OC(OC3C2OC(O1)(C)C)(C)C)N

  • Synonyms:
  • 2,3:4,5-Bis-O-(1-methylethylidene) β-<span class="text-smallcaps">D</span>-fructopyranose sulfamate
  • 2,3:4,5-Bis-O-(1-methylethylidene) β-D-fructopyranose sulfamate
  • 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
  • 5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran, β-<span class="text-smallcaps">D</span>-fructopyranose deriv.
  • Epitoma
  • Epitomax
  • McN 4853
  • Qudexy XR
  • Rwj 17021
  • Sincronil
  • See more synonyms
  • TPM
  • Toiramate
  • Topamac
  • Topamax
  • Topimax
  • Topina
  • Topiragen
  • Topomax
  • Tracrium
  • Trokendi XR
  • β-<span class="text-smallcaps">D</span>-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
  • β-<span class="text-smallcaps">D</span>-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
  • β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
  • β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
  • Topiramate
  • 5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran, β-D-fructopyranose deriv.
  • 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulfamate
  • Topiramato [INN-Spanish]
  • 1-O-Sulfamoyl-2-O,3-O:4-O,5-O-diisopropylidene-β-D-fructopyranose
  • Topiramate Synonyms Topamax
  • TopiramateTopamax
  • Topiramate solution
  • 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranoside sulfamate
  • 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranosidesulfamate
  • Topiramate (150 mg)
  • Tipiramato [Spanish]
  • 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose sulfamate
  • RWJ-17021-000
  • TopiraMate(McN-4853,RWJ-17021,TopaMax)
  • Tipiramate [French]
  • Topiramic acid
  • .beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
  • McN 4853, RWJ 17021, Topamax, 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate
  • 1-O-Sulfamoyl-2-O,3-O:4-O,5-O-bis(1-methylethylidene)-β-D-fructopyranose
  • TopiraMate API
  • 2,3:4,5-Bis-O-(1-methylethylidene)--D-fuctopyranose Sulfamate, McN-4853, RWJ-17021-000, Topamax
  • ((3aS,5aR,8aR,8bS)-2,2,7,7-tetraMethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)Methyl sulfaMate
  • ((3AS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl
  • 2,3:4,5-Bis-O-(1-Methylethylidene)-β-D-fuctopyranose 1-SulfaMate
  • Topiramatum [INN-Latin]
  • TopiriMate-d12
  • 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-B-D-FUCTO-PYRANOSE SULFAMATE
  • Topiramate [USAN:BAN:INN]
  • PHARMACEUTICAL RAW MATERIAL: TOPIRAMATEUSP
  • topiramatum [Latin]
  • 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranossulfamate
  • 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-36-D-FRUCTO-PYRANOSE SULFAMATE
  • 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamate
  • 2,3:4,5-Di-O-isopropylidene-1-O-sulfamoyl-beta-D-fructopyranose
  • Topiramate, >=98%
  • 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-BETA-D-FUCTOPYRANOSE SULFAMATE
  • 2,3:4,5-Bis-O-(1-methylethylidene)-b-D-fuctopyranose Sulfamate, McN-4853, RWJ-17021-000, Topamax
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70mg115.00 €
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Topiramate

CAS:97240-79-4

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Topiramate

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Topiramate

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Topiramate

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Ref: 86-MM1348.00

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Topiramate-13C6

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Ref: TR-T540251

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Topiramate - Bio-X ™

CAS:97240-79-4

Ref: 3D-BT167048

100mg135.00 €
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Topiramate, 98%

CAS:97240-79-4

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