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CAS 97748-75-9

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Uridine, 2'-azido-2'-deoxy-5-methyl-

Description:
Uridine, 2'-azido-2'-deoxy-5-methyl- is a modified nucleoside that features an azido group at the 2' position and a methyl group at the 5' position of the ribose sugar. This compound is part of the broader category of nucleoside analogs, which are often studied for their potential applications in antiviral and anticancer therapies. The presence of the azido group can enhance the compound's reactivity and may facilitate incorporation into nucleic acids, potentially affecting their biological activity. The methyl group at the 5' position can influence the stability and binding affinity of the nucleoside to various enzymes and receptors. As a synthetic derivative of uridine, this compound may exhibit unique pharmacological properties compared to its natural counterparts. Its chemical structure allows for various modifications that can be explored in medicinal chemistry, particularly in the development of therapeutics targeting RNA viruses or in gene therapy applications. Overall, the characteristics of this compound make it a subject of interest in biochemical research and drug development.
Formula:C10H13N5O5
Synonyms:
  • 2'-Azido-2'-deoxy-5-methyl uridine
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Found 2 products.
  • 2'-Azido-2'-deoxy-5-methyluridine
    Targetmol
    + Info

    2'-Azido-2'-deoxy-5-methyluridine

    CAS:
    2'-Azido-2'-deoxy-5-methyluridine is a Nucleoside Derivative - Azido-nucleoside, 2'-Modified nucleoside, 5-Modified pyrimidine nucleoside.
    Formula:C10H13N5O5
    Color and Shape:Solid
    Molecular weight:283.24

    Ref: TM-TNU0966

  • 2'-Azido-2'-deoxy-5-methyluridine
    Biosynth
    + Info

    2'-Azido-2'-deoxy-5-methyluridine

    CAS:
    <p>2'-Azido-2'-deoxy-5-methyluridine (2'-Aza-dUMP) is an antiviral agent that inhibits the replication of HIV. It has been shown to be an activator of DNA, RNA, and phosphoramidites. This compound is an analog of thymidine and is structurally similar to 5-fluoro-2',3'-dideoxyuridine. 2'-Aza-dUMP has been used as a substrate for DNA synthesis in order to produce oligonucleotides for use in gene therapy. 2'-Aza-dUMP also induces apoptosis in cancer cells and has shown anti-inflammatory properties.</p>
    Formula:C10H13N5O5
    Purity:Min. 95%
    Molecular weight:283.24 g/mol

    Ref: 3D-NA158312

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