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CAS 97867-33-9

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Ciprofloxacin lactate

Description:
Ciprofloxacin lactate is a derivative of ciprofloxacin, a broad-spectrum antibiotic belonging to the fluoroquinolone class. It is primarily used to treat bacterial infections by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and repair. The lactate form enhances its solubility and stability, making it suitable for parenteral administration. This compound typically appears as a white to off-white crystalline powder and is soluble in water, which facilitates its use in injectable formulations. Ciprofloxacin lactate exhibits a spectrum of activity against both Gram-positive and Gram-negative bacteria, making it effective for various infections, including respiratory and urinary tract infections. Its pharmacokinetics involve rapid absorption and distribution, with a half-life that allows for convenient dosing schedules. However, like other fluoroquinolones, it may have side effects, including gastrointestinal disturbances and potential effects on tendons. Careful consideration of contraindications and interactions with other medications is essential when prescribing ciprofloxacin lactate.
Formula:C17H18FN3O3·C3H6O3
InChI:InChI=1S/C17H18FN3O3.C3H6O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;1-2(4)3(5)6/h7-10,19H,1-6H2,(H,23,24);2,4H,1H3,(H,5,6)
InChI key:InChIKey=NRBJWZSFNGZBFQ-UHFFFAOYSA-N
SMILES:O=C1C=2C(N(C=C1C(O)=O)C3CC3)=CC(=C(F)C2)N4CCNCC4.C(C(O)=O)(C)O
Synonyms:
  • 1-Cyclopropyl-6-Fluoro-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydroquinoline-3-Carboxylic Acid - 2-Hydroxypropanoic Acid (1:1)
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid lactate
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, 2-hydroxypropanoate (1:1)
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, mono(2-hydroxypropanoate)
  • Propanoic acid, 2-hydroxy-, compd. with 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid (1:1)
  • Ciprofloxacin lactate
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