CAS 97885-44-4

Boc-Lys(Tfa)-AMC

CAS: 97885-44-4

Fluorogenic substrate for assaying histone deacetylase (HDAC) 4, 5 and 7 activity in a protease-coupled assay. Suitable substrate for HDAC 8. HDAC cleavage yields Boc-Lys-AMC.

Formula: C₂₃H₂₈F₃N₃O₆

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 499.49

Ref: 01-4060676

1,1-Dimethylethyl N-[(1S)-1-[[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]carbonyl]-5-[(trifluoroacetyl)amino]pentyl]carbamate

CAS: 97885-44-4

1,1-Dimethylethyl N-[(1S)-1-[[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]carbonyl]-5-[(trifluoroacetyl)amino]pentyl]carbamate

Formula: C₂₃H₂₈F₃N₃O₆

Purity: ≥98%

Molecular weight: 499.48

Ref: 54-PC1031640

Boc-Lys(Tfa)-AMC

Controlled Product

CAS: 97885-44-4

Formula: C₂₃H₂₈F₃N₃O₆

Color and Shape: Neat

Molecular weight: 499.48

Ref: TR-B657078

Boc-Lys(Tfa)-AMC

CAS: 97885-44-4

Boc-Lys(Tfa)-AMC is a small molecule that inhibits the acetylation of histone H3 and has anticancer activity. Acetylation increases the rate of transcription and replication, whereas Boc-Lys(Tfa)-AMC inhibits this process by preventing acetylation. This drug also binds to δ-opioid receptors in cancer cells, triggering a redox signal that leads to inhibition of cancer cell proliferation. The mechanism of this drug's anticancer activity is unknown, but it may be due to its ability to inhibit enzyme activities or disulfide bond formation in vivo.

Formula: C₂₃H₂₈F₃N₃O₆

Purity: Min. 95%

Molecular weight: 499.48 g/mol

Ref: 3D-FB110609