CAS 98-79-3

L-Pyroglutamic acid

Description:

L-Pyroglutamic acid, also known as 5-oxoproline, is a cyclic derivative of the amino acid glutamic acid. It is characterized by its five-membered lactam structure, which includes a carbonyl group and an amine group, contributing to its unique properties. This compound is a non-proteinogenic amino acid and plays a role in various biochemical processes, including the synthesis of glutathione, an important antioxidant in the body. L-Pyroglutamic acid is typically a white crystalline solid that is soluble in water and exhibits a slightly acidic nature due to the presence of the carboxylic acid group. It is often used in the pharmaceutical and cosmetic industries, as well as in nutritional supplements, due to its potential benefits in cognitive function and metabolic processes. Additionally, it has been studied for its role in cellular signaling and as a precursor in the synthesis of other biologically relevant compounds. Its CAS number, 98-79-3, is used for identification in chemical databases and regulatory contexts.

Formula: C₅H₇NO₃

InChI: InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1

InChI key: InChIKey=ODHCTXKNWHHXJC-VKHMYHEASA-N

SMILES: C(O)(=O)[C@H]1NC(=O)CC1

Synonyms:

• (-)-2-Pyrrolidone-5-carboxylic acid
• (2S)-5-Oxopyrrolidine-2-carboxylic acid
• (2S)-5-oxopyrrolidine-2-carboxylate
• (5S)-2-Oxopyrrolidine-5-carboxylic acid
• (S)-(-)-2-Pyrrolidinone-5-carboxylic acid
• (S)-(-)-γ-Butyrolactam-γ-carboxylic acid
• (S)-5-Oxo-1H-pyrrolidine-2-carboxylic acid
• (S)-5-Oxo-2-pyrrolidinecarboxylic acid
• (S)-5-Oxoproline
• (S)-Pyroglutamic acid
• 2-<span class="text-smallcaps">L</span>-Pyrrolidone-5-carboxylic acid
• 2-L-Pyrrolidone-5-carboxylic acid
• 2-Oxopyrrolidine-5(S)-carboxylic acid
• 2-Pyrrolidinone-5-carboxylic acid
• 2-Pyrrolidon-5-carboxylic acid
• 2-Pyrrolidone Carboxylic Acid
• 5-Carboxy-2-pyrrolidinone
• 5-Oxo-<span class="text-smallcaps">L</span>-proline
• 5-Oxo-L-proline
• 5-Oxoproline
• 5-Oxopyrrolidine-2-carboxylic acid
• 5-Pyrrolidinone-2-carboxylic acid
• 5-Pyrrolidone-2-carboxylic acid
• <span class="text-smallcaps">L</span>-(-)-Pyroglutamic acid
• <span class="text-smallcaps">L</span>-2-Pyrrolidone-5-carboxylic acid
• <span class="text-smallcaps">L</span>-5-Carboxy-2-pyrrolidinone
• <span class="text-smallcaps">L</span>-5-Oxo-2-pyrrolidinecarboxylic acid
• <span class="text-smallcaps">L</span>-5-Oxoproline
• <span class="text-smallcaps">L</span>-Glutamic acid, γ-lactam
• <span class="text-smallcaps">L</span>-Glutimic acid
• <span class="text-smallcaps">L</span>-Glutiminic acid
• <span class="text-smallcaps">L</span>-Proline, 5-oxo-
• <span class="text-smallcaps">L</span>-Pyroglutamine
• <span class="text-smallcaps">L</span>-Pyrrolidinonecarboxylic acid
• <span class="text-smallcaps">L</span>-Pyrrolidonecarboxylic acid
• Acide pidolique
• Acido Pidolico
• Ajidew A 100
• Glutimic acid
• Glutiminic Acid
• H-Pyr-OH
• L-2-Pyrrolidone-5-carboxylic acid
• L-5-Carboxy-2-pyrrolidinone
• L-5-Oxo-2-pyrrolidinecarboxylic acid
• L-5-Oxoproline
• L-5-Pyrrolidone-2-carboxylic acid
• L-Glutamic acid, γ-lactam
• L-Glutimic acid
• L-Glutiminic acid
• L-Proline, 5-oxo-
• L-Pyroglutamic acid
• L-Pyrpglutamic Acid
• L-Pyrrolidinonecarboxylic acid
• L-Pyrrolidonecarboxylic acid
• L-pyro glutamic acid
• Nsc 143034
• Oxoproline
• Oxopyrrolidinecarboxylic acid
• PCA
• Pca 50
• Pidolic Acid
• Pidolidone
• Pidolinsaure
• Proline, 5-oxo-, <span class="text-smallcaps">L</span>-
• Proline, 5-oxo-, L-
• Pyr-OH
• Pyroglutamic Acid
• Pyroglutamicacid
• Pyroglutamine
• Pyrrolid-2-One-5-Carboxylic Acid
• Pyrrolidinonecarboxylic acid
• Pyrrolidone-5-carboxylic acid
• Pyrrolidonecarboxylic Acid
• Take Off Booster

H-Pyr-OH

CAS: 98-79-3

M03204 - H-Pyr-OH

Formula: C₅H₇NO₃

Purity: 98.00%

Color and Shape: Crystalline,Powder

Molecular weight: 129.115

Ref: 10-M03204

(S)-(-)-2-Pyrrolidinone-5-carboxylic acid, 98+%

CAS: 98-79-3

(S)-(-)-2-Pyrrolidinone-5-carboxylic acid is used as a building block for pharmaceuticals and asymmetric synthesis. It Is also used as a resolving agent for chiral bases and in an efficient synthesis of quinolizidine and indolizidine alkaloids. This Thermo Scientific Chemicals brand product was orig

Formula: C₅H₇NO₃

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 129.12

Ref: 02-L11711

Pyr-OH

CAS: 98-79-3

A versatile chiral synthon. Panday et al. reviewed its use in asymmetric synthesis.

Formula: C₅H₇NO₃

Purity: > 99%

Color and Shape: White

Molecular weight: 129.12

Ref: 01-4026127

PIDOLIC ACID CRS

CAS: 98-79-3

PIDOLIC ACID CRS

Formula: C₅H₇NO₃

Color and Shape: Added

Molecular weight: 129.114

Ref: 41-Y0000123

Pyroglutamic Acid ((S)-5-Oxopyrrolidine-2-carboxylic acid)

CAS: 98-79-3

Lactams, nesoi

Formula: C₅H₇NO₃

Color and Shape: Colorless Crystals

Molecular weight: 129.12

Ref: 45-1589029

(2S)-5-Oxopyrrolidine-2-carboxylic acid

CAS: 98-79-3

(2S)-5-Oxopyrrolidine-2-carboxylic acid

Formula: C₅H₇NO₃

Purity: ≥95%

Color and Shape: White Solid-Powder

Molecular weight: 129.11398

Ref: 54-OR8965

L-Pyroglutamic acid

CAS: 98-79-3

L-Pyroglutamic acid

Formula: C₅H₇NO₃

Purity: ≥98%

Molecular weight: 129.11

Ref: 54-BUP19618

H-Pyr-OH

CAS: 98-79-3

(S)-5-Oxopyrrolidine-2-carboxylic acid

Formula: C₅H₇NO₃

Purity: 98%

Molecular weight: 129.11

Ref: IN-DG23339

L-Pyroglutamic acid

CAS: 98-79-3

L-Pyroglutamic acid elevates blood levels, possibly indicating glutathione or glutamine metabolism issues.

Formula: C₅H₇NO₃

Purity: 99.89% - 99.94%

Color and Shape: Solid

Molecular weight: 129.11

Ref: TM-T0507

(2S)-5-oxopyrrolidine-2-carboxylic acid

CAS: 98-79-3

Formula: C₅H₇NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 129.1140

Ref: IN-DA00IK0B

L-Pyroglutamic Acid

CAS: 98-79-3

Formula: C₅H₇NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 129.12

Ref: 4Z-PG-355

L-Pyroglutamic acid

CAS: 98-79-3

Formula: C₅H₇NO₃

Purity: (Titration) 98.0 - 102.0 %

Color and Shape: White or almost white crystalline powder

Molecular weight: 129.12

Ref: 7W-GM2961

Pidolic Acid

Controlled Product

CAS: 98-79-3

Formula: C₅H₇NO₃

Color and Shape: Neat

Molecular weight: 129.11

Ref: 86-MM3413.01

L-Pyroglutamic Acid

CAS: 98-79-3

Formula: C₅H₇NO₃

Purity: >97.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 129.12

Ref: 3B-P0573

L-Pyroglutamic Acid

Controlled Product

CAS: 98-79-3

Applications L-Pyroglutamic acid is an amino acid that is used in the synthesis of peptides. It has also been observed to convert when placed at the N-terminus in vivo to create IgG2 antibodies.
References Wirths, O. et al.: J. Biol. Chem., 53, 41517 (2010); Liu, Y.D. et al.: J. Biol. Chem., 286, 11211 (2011);

Formula: C₅H₇NO₃

Color and Shape: Neat

Molecular weight: 129.11

Ref: TR-P997480

L-Pyroglutamic Acid extrapure, 99%

CAS: 98-79-3

Formula: C₅H₇NO₃

Purity: min. 99.0%

Color and Shape: White to off-white, Crystalline powder, Clear

Molecular weight: 129.12

Ref: SR-77577

L-Pyroglutamic Acid

CAS: 98-79-3

Formula: C₅H₇NO₃

Molecular weight: 129.12

Ref: ST-EA-CP-G19008

(S)-(-)-2-Pyrrolidone-5-carboxylic acid

CAS: 98-79-3

A hydrophilic and hygroscopic element of natural moisturizing factor (NMF) that maintains hydration of the skin stratum corneum.  Elevated levels of pyroglutamic acid in the blood, urine and brain lead to metabolic acidosis. Enhances blood circulation in the brain. Conjugation of pyroglutamic acid with Apaf-1 inhibitor peptoid 1, as a polymeric carrier, improves anti-apoptotic activity.

Formula: C₅H₇NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 129.11 g/mol

Ref: 3D-FP31392