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CAS 98092-14-9

:

Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

Description:
Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH, with the CAS number 98092-14-9, is a synthetic peptide that consists of a sequence of amino acids, including isovaleryl, phenylalanine (Phe), norleucine (Nle), statine (Sta), and alanine (Ala), capped with a hydroxyl group (OH). This compound is characterized by its unique structure, which influences its biological activity and potential applications in pharmacology and biochemistry. The presence of the isovaleryl group may enhance lipophilicity, potentially affecting membrane permeability and interaction with biological targets. The incorporation of non-standard amino acids like norleucine and statine can impart specific properties, such as increased stability or altered binding affinity to receptors. Peptides like Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH are often studied for their roles in signaling pathways, therapeutic applications, and as tools in drug design. Understanding the characteristics of such peptides is crucial for exploring their functionality and potential uses in various scientific fields.
Formula:C39H65N5O9
InChI:InChI=1/C39H65N5O9/c1-9-10-16-29(43-37(51)31(42-34(47)19-25(6)7)20-27-14-12-11-13-15-27)39(53)44(35(48)21-32(45)28(40)17-23(2)3)38(52)26(8)41-30(18-24(4)5)33(46)22-36(49)50/h11-15,23-26,28-33,41,45-46H,9-10,16-22,40H2,1-8H3,(H,42,47)(H,43,51)(H,49,50)/t26-,28-,29-,30?,31-,32-,33-/m0/s1
SMILES:CCCC[C@@H](C(=O)N(C(=O)C[C@@H]([C@H](CC(C)C)N)O)C(=O)[C@H](C)NC(CC(C)C)[C@H](CC(=O)O)O)N=C([C@H](Cc1ccccc1)N=C(CC(C)C)O)O
Synonyms:
  • N-(3-methylbutanoyl)-L-phenylalanyl-N-[(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl]-N-[(2S)-2-({1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl}amino)propanoyl]-L-norleucinamide
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Found 2 products.
  • Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH
    TRC
    + Info

    Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

    Controlled Product
    CAS:
    Formula:C39H65N5O9
    Color and Shape:Neat
    Molecular weight:747.962

    Ref: TR-I247390

    25mg
    31,279.00€
  • Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH
    Biosynth
    + Info

    Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

    CAS:
    <p>Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH (IVAS) is a small molecule that has been shown to be an angiotensin system inhibitor. IVAS blocks the binding site of the angiotensin receptor and prevents the activation of this system. This effect is dose dependent and can be used to treat high blood pressure in humans. IVAS is a long-acting drug and has been shown to be effective in primates as well as humans. The drug is rapidly absorbed from the gastrointestinal tract and eliminated by metabolism, mainly through hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. IVAS also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>
    Formula:C39H65N5O9
    Purity:Min. 95%
    Molecular weight:747.96 g/mol

    Ref: 3D-FI49358

    1mg
    863.00€
    2mg
    1,013.00€
    5mg
    1,670.00€
    10mg
    2,904.00€