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CAS 981-34-0

:

Betamethasone 9,11-epoxide

Description:
Betamethasone 9,11-epoxide, with the CAS number 981-34-0, is a synthetic corticosteroid that exhibits anti-inflammatory and immunosuppressive properties. It is derived from betamethasone, a potent glucocorticoid, and features an epoxide functional group that enhances its biological activity. This compound is typically used in the treatment of various inflammatory and autoimmune conditions, including skin disorders, allergies, and certain types of arthritis. Betamethasone 9,11-epoxide is characterized by its high potency and efficacy, often leading to rapid therapeutic effects. Its mechanism of action involves the modulation of gene expression, resulting in decreased production of pro-inflammatory cytokines and other mediators. The substance is usually administered topically or systemically, depending on the condition being treated. As with other corticosteroids, potential side effects may include suppression of the hypothalamic-pituitary-adrenal (HPA) axis, increased risk of infections, and metabolic changes. Proper dosing and monitoring are essential to minimize adverse effects while maximizing therapeutic benefits.
Formula:C22H28O5
InChI:InChI=1S/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)22(15)18(27-22)10-20(16,3)21(12,26)17(25)11-23/h6-7,9,12,15-16,18,23,26H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,18-,19-,20-,21-,22+/m0/s1
InChI key:InChIKey=GBDXNHBVYAMODG-DEGNENOVSA-N
SMILES:C[C@@]12[C@@]34[C@]([C@]5([C@](C)(C[C@@]3(O4)[H])[C@](C(CO)=O)(O)[C@@H](C)C5)[H])(CCC1=CC(=O)C=C2)[H]
Synonyms:
  • (9Beta,11Beta,16Beta)-17,21-Dihydroxy-16-Methyl-9,11-Epoxypregna-1,4-Diene-3,20-Dione
  • (9β,11β,16β)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 9,11-Epoxy-9H-cyclopenta[a]phenanthrene, pregna-1,4-diene-3,20-dione deriv.
  • 9,11β-Epoxy-17,21-dihydroxy-16β-methyl-9β-pregna-1,4-diene-3,20-dione
  • 9-Beta,11-Beta-Epoxy-17-Alpha,21-Dihydroxy-16-Beta-Methylene-Pregna-1,4-Diene-3,20-Dione
  • 9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
  • 9β-Pregna-1,4-diene-3,20-dione, 9,11β-epoxy-17,21-dihydroxy-16β-methyl-
  • Betamethasone 9,11-epoxide
  • Db11
  • Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-16-methyl-, (9β,11β,16β)-
  • See more synonyms
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Found 10 products.