CAS 98105-99-8
:Sarafloxacin
Description:
Sarafloxacin is a synthetic fluoroquinolone antibiotic that is primarily used in veterinary medicine, particularly for treating bacterial infections in livestock and poultry. It exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Sarafloxacin is characterized by its chemical structure, which includes a bicyclic core and a fluorine atom that enhances its potency and spectrum of activity. The compound is typically administered orally and is known for its relatively high bioavailability. Its pharmacokinetics involve rapid absorption and distribution, with a moderate half-life, allowing for effective treatment regimens. However, the use of sarafloxacin has raised concerns regarding antibiotic resistance and its potential impact on human health, leading to regulatory scrutiny in some regions. As with other antibiotics, appropriate usage is essential to mitigate the development of resistant bacterial strains.
Formula:C20H17F2N3O3
InChI:InChI=1S/C20H17F2N3O3/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24/h1-4,9-11,23H,5-8H2,(H,27,28)
InChI key:InChIKey=XBHBWNFJWIASRO-UHFFFAOYSA-N
SMILES:O=C1C=2C(N(C=C1C(O)=O)C3=CC=C(F)C=C3)=CC(=C(F)C2)N4CCNCC4
Synonyms:- 3-Quinolinecarboxylic Acid, 6-Fluoro-1-(4-Fluorophenyl)-1,4-Dihydro-4-Oxo-7-(1-Piperazinyl)-
- 6-Fluoro-1-(4-Fluorophenyl)-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydroquinoline-3-Carboxylic Acid
- 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
- 98105-99-8
- A 56620
- Pd 121960
- Sarafloxacin
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Found 14 products.
Sarafloxacin
CAS:6-Fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acidFormula:C20H17F2N3O3Purity:98%Molecular weight:385.36Sarafloxacin
CAS:Applications Sarafloxacin is a quinolone antibiotic drug that was discontinued in 2001. Useful for biological studies and can be detected with colloidal gold test strips.
References Jia, F., et al.: Agric. Biotechnol., 8, 172 (2019)Formula:C20H17F2N3O3Color and Shape:NeatMolecular weight:385.36Sarafloxacin
CAS:Sarafloxacin is an antimicrobial agent that belongs to the quinolone class. It has a chemical stability that allows for use in an injection solution, which may be useful for treating infectious diseases. Sarafloxacin has been shown to be active against human pathogens such as Haemophilus influenzae and Neisseria meningitides. This drug also shows activity against other human pathogens such as Streptococcus pneumoniae, Chlamydia pneumoniae, and Mycoplasma pneumoniae. Sarafloxacin inhibits bacterial growth by acting on DNA gyrase, a type II topoisomerase, and RNA polymerase. The fluorescence detector detects fluorescence emitted from sarafloxacin-treated cells in the presence of two different wavelengths of light. This method is used in conjunction with LC-MS/MS to identify the antibiotic’s molecular targets and determine its mechanism of action.Formula:C20H17F2N3O3Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:385.36 g/molSarafloxacin
CAS:Sarafloxacin (A56620) has antibacterial activities against Gram-positive and Gram-negative bacteria.Formula:C20H17F2N3O3Purity:97.06% - 98.94%Color and Shape:SolidMolecular weight:385.36
