CymitQuimica logo

CAS 98210-71-0

:

Boc-Gly-Gly-Leu-pNA

Description:
Boc-Gly-Gly-Leu-pNA, with the CAS number 98210-71-0, is a synthetic peptide substrate commonly used in biochemical research, particularly in the study of proteolytic enzymes. The "Boc" (tert-butyloxycarbonyl) group serves as a protective group for the amino terminus, enhancing the stability and solubility of the peptide. The sequence consists of two glycine (Gly) residues, a leucine (Leu) residue, and a para-nitroanilide (pNA) moiety, which is a chromogenic group that allows for the quantification of enzymatic activity through colorimetric assays. This compound is typically utilized in assays to measure the activity of serine proteases and other enzymes that cleave peptide bonds. Its characteristics include good solubility in organic solvents and aqueous solutions, making it versatile for various experimental conditions. The presence of the pNA group enables the detection of enzymatic cleavage by producing a measurable color change, facilitating the study of enzyme kinetics and inhibition. Overall, Boc-Gly-Gly-Leu-pNA is a valuable tool in peptide chemistry and enzymology.
Formula:C21H31N5O7
InChI:InChI=1S/C21H31N5O7/c1-13(2)10-16(19(29)24-14-6-8-15(9-7-14)26(31)32)25-18(28)12-22-17(27)11-23-20(30)33-21(3,4)5/h6-9,13,16H,10-12H2,1-5H3,(H,22,27)(H,23,30)(H,24,29)(H,25,28)/t16-/m0/s1
InChI key:KKTHNFIJCQMQOR-INIZCTEOSA-N
SMILES:CC(C)C[C@@H](C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)CNC(=O)CNC(=O)OC(C)(C)C
Synonyms:
  • Subtilisin A Substrate I
  • Subtilisin A Substrate I, Colorimetric
  • L-Leucinamide,N-[(1,1-dimethylethoxy)carbonyl]glycylglycyl-N-(4-nitrophenyl)-
Found 2 products.