CAS 98495-35-3

pglu-asp-pro-phe-leu-arg-phe amide

Description:

The chemical substance known as "pglu-asp-pro-phe-leu-arg-phe amide," with the CAS number 98495-35-3, is a peptide composed of a specific sequence of amino acids. This peptide features a combination of polar and non-polar residues, which contributes to its unique properties and potential biological activities. The presence of amino acids such as glutamic acid (pglu), aspartic acid (asp), proline (pro), phenylalanine (phe), leucine (leu), arginine (arg), and another phenylalanine (phe) suggests that it may exhibit various interactions, including hydrogen bonding and hydrophobic interactions, influencing its conformation and stability. The amide group at the end of the peptide chain indicates that it may have enhanced stability compared to free amino acids. Peptides like this one can play significant roles in biological processes, including signaling and enzyme activity, and may have applications in pharmaceuticals and biotechnology. However, specific characteristics such as solubility, melting point, and biological activity would require empirical data for precise evaluation.

Formula: C₄₄H₆₁N₁₁O₁₀

InChI: InChI=1/C44H61N11O10/c1-25(2)21-31(40(62)50-28(15-9-19-48-44(46)47)38(60)51-30(37(45)59)22-26-11-5-3-6-12-26)52-41(63)32(23-27-13-7-4-8-14-27)53-42(64)34-16-10-20-55(34)43(65)33(24-36(57)58)54-39(61)29-17-18-35(56)49-29/h3-8,11-14,25,28-34H,9-10,15-24H2,1-2H3,(H2,45,59)(H,49,56)(H,50,62)(H,51,60)(H,52,63)(H,53,64)(H,54,61)(H,57,58)(H4,46,47,48)/t28-,29-,30-,31-,32-,33-,34-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](Cc1ccccc1)C(=N)O)O)O)N=C([C@H](Cc1ccccc1)N=C([C@@H]1CCCN1C(=O)[C@H](CC(=O)O)N=C([C@@H]1CCC(=N1)O)O)O)O

Synonyms:

• Pyr-Asp-Pro-Phe-Leu-Arg-Phe-NH2
• 5-oxo-L-prolyl-L-alpha-aspartyl-L-prolyl-L-phenylalanyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-L-phenylalaninamide
• Fmrf-Like Peptide

Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa

CAS: 98495-35-3

FMRF is a 4-residue neuropeptide from Helix aspersa snail muscles.

Formula: C₄₄H₆₁N₁₁O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 904.02

Ref: TM-TP1057

Pyr-Asp-Pro-Phe-Leu-Arg-Phe-NH2

CAS: 98495-35-3

Pyr-Asp-Pro-Phe-Leu-Arg-Phe-NH2 is a tetrapeptide that has been shown to inhibit the action of acetylcholinesterase and increase the levels of acetylcholine in the brain. Pyr-Asp-Pro-Phe-Leu-Arg-Phe-NH2 can be used as a potential drug for improving cognition and memory. It also has been found to have positive effects on blood pressure, and may be effective in treating cardiac arrhythmias. Pyr-Asp-Pro Phe Leu Arg Phe NH2 has been shown to bind to nicotinic acetylcholine receptors in ganglia, which may lead to physiological effects such as muscle contraction. The peptide is stable at neutral pH but breaks down at acidic or basic pH levels. Pyr Asp Pro Phe Leu Arg Phe NH2 can be purified by gel chromatography.

Formula: C₄₄H₆₁N₁₁O₁₀

Purity: Min. 95%

Molecular weight: 904.02 g/mol

Ref: 3D-FP110406