CAS 98769-84-7

Reboxetine mesylate

Description:

Reboxetine mesylate is a pharmaceutical compound primarily used as an antidepressant, classified as a selective norepinephrine reuptake inhibitor (NRI). It is the mesylate salt form of reboxetine, which enhances its solubility and stability. The compound is characterized by its ability to increase norepinephrine levels in the synaptic cleft by inhibiting its reuptake into presynaptic neurons, thereby improving mood and alleviating symptoms of depression. Reboxetine mesylate is typically administered orally and is known for its relatively favorable side effect profile compared to other antidepressants. Its chemical structure includes a piperidine ring, contributing to its pharmacological activity. The substance is generally well-absorbed in the gastrointestinal tract, with a half-life that allows for once-daily dosing. As with any medication, it is essential to consider potential side effects, contraindications, and interactions with other drugs. Overall, reboxetine mesylate represents a significant option in the treatment of major depressive disorder, particularly for patients who may not respond well to traditional selective serotonin reuptake inhibitors (SSRIs).

Formula: C₁₉H₂₃NO₃·CH₄O₃S

InChI: InChI=1/C19H23NO3.CH4O3S/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4)/t18-,19-;/s2

InChI key: InChIKey=CGTZMJIMMUNLQD-QLJMZTSGNA-N

SMILES: [C@@H](OC1=C(OCC)C=CC=C1)(C2=CC=CC=C2)[C@]3(CNCCO3)[H].S(C)(=O)(=O)O

Synonyms:

• (2S)-2-[(S)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine methanesulfonate
• 2-[(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate
• Davedax
• Edronax
• Fce 20124
• Morpholine, 2-[(2-ethoxyphenoxy)phenylmethyl]-, (R*,R*)-(±)-, methanesulfonate
• Morpholine, 2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel-, methanesulfonate
• Morpholine, 2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel-, methanesulfonate (1:1)
• Pnu 155905E
• Pnu 155950E
• Reboxetine mesilate

Reboxetine Mesilate 1.0 mg/ml in Methanol (as free base)

CAS: 98769-84-7

Color and Shape: Single Solution

Ref: 61-AMP1613.00-01

Reboxetine Mesilate

CAS: 98769-84-7

Color and Shape: Neat

Ref: 61-FOR1613.00

Morpholine, 2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel-,methanesulfonate

CAS: 98769-84-7

Formula: C₂₀H₂₇NO₆S

Purity: %

Color and Shape: Solid

Molecular weight: 409.4965

Ref: IN-DA00IK62

Reboxetine mesylate

CAS: 98769-84-7

Formula: C₁₉H₂₃NO₃·CH₃SO₃H

Purity: ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 409.50

Ref: 7W-GM1906

Reboxetine mesylate

CAS: 98769-84-7

Reboxetine mesylate

Purity: ≥98%

Molecular weight: 409.5g/mol

Ref: 54-BUP10597

Reboxetine Mesylate

CAS: 98769-84-7

Formula: C₁₉H₂₃NO₃·CH₄O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 313.40 96.11

Ref: 4Z-R-082005

Reboxetine Mesilate

Controlled Product

CAS: 98769-84-7

Formula: C₁₉H₂₃NO₃·CH₄O₃S

Color and Shape: Neat

Molecular weight: 409.50

Ref: 86-MM1613.00

Reboxetine mesylate

CAS: 98769-84-7

Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).

Formula: C₁₉H₂₃NO₃·CH₄O₃S

Purity: 99.18% - 99.87%

Color and Shape: Tan Or Off-White Cyrstalline Solid

Molecular weight: 409.5

Ref: TM-T6963

Reboxetine Mesylate

Controlled Product

CAS: 98769-84-7

Applications A selective noradrenaline reuptake inhibitor. Antidepressant.
References Cocchiara, G., et al.: Eur. J. Drug. Metab. Pharmacokinet., 16, 231 (1991), Pelliazoni, C., et al.: Biopharm. Drug. Dispos., 17, 623 (1996),

Formula: C₁₉H₂₃NO₃·CH₄O₃S

Color and Shape: Off White Solid

Molecular weight: 409.50

Ref: TR-R142000

Reboxetine mesylate

Controlled Product

CAS: 98769-84-7

Reboxetine mesylate is a drug that belongs to the class of tricyclic antidepressants. It is a selective and potent inhibitor of neuronal reuptake of norepinephrine (noradrenaline).  Reboxetine also interacts with neurokinin-1 receptor, which may affect locomotor activity and hippocampal formation, resulting in effects to memory and learning. It has been shown to be effective in the treatment of symptoms related to depression and Parkinson's disease.

Formula: C₂₀H₂₇NO₆S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 409.5 g/mol

Ref: 3D-FR27687

Reboxetine mesylate - Bio-X ™

Controlled Product

CAS: 98769-84-7

Reboxetine mesylate is a drug that belongs to the class of tricyclic antidepressants. It is a selective and potent inhibitor of neuronal reuptake of norepinephrine (noradrenaline).  Reboxetine also interacts with neurokinin-1 receptors, which may affect locomotor activity and hippocampal formation, resulting in effects to memory and learning. It has been shown to be effective in the treatment of symptoms related to depression and Parkinson's disease.

Formula: C₂₀H₂₇NO₆S

Purity: Min. 98 Area-%

Molecular weight: 409.5 g/mol

Ref: 3D-BR164331

Reboxetine Mesylate

CAS: 98769-84-7

Formula: C₁₉H₂₃NO₃CH₄O₃S

Molecular weight: 313.4 : 96.1

Ref: ST-EA-CP-R32002