CAS 98769-84-7

Reboxetine mesylate

Description:

Reboxetine mesylate is a pharmaceutical compound primarily used as an antidepressant, classified as a selective norepinephrine reuptake inhibitor (NRI). It is the mesylate salt form of reboxetine, which enhances its solubility and stability. The compound is characterized by its ability to increase norepinephrine levels in the synaptic cleft by inhibiting its reuptake into presynaptic neurons, thereby improving mood and alleviating symptoms of depression. Reboxetine mesylate is typically administered orally and is known for its relatively favorable side effect profile compared to other antidepressants. Its chemical structure includes a piperidine ring, contributing to its pharmacological activity. The substance is generally well-absorbed in the gastrointestinal tract, with a half-life that allows for once-daily dosing. As with any medication, it is essential to consider potential side effects, contraindications, and interactions with other drugs. Overall, reboxetine mesylate represents a significant option in the treatment of major depressive disorder, particularly for patients who may not respond well to traditional selective serotonin reuptake inhibitors (SSRIs).

Formula:C₁₉H₂₃NO₃·CH₄O₃S

InChI:InChI=1/C19H23NO3.CH4O3S/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4)/t18-,19-;/s2

InChI key:InChIKey=CGTZMJIMMUNLQD-QLJMZTSGNA-N

SMILES:[C@@H](OC1=C(OCC)C=CC=C1)(C2=CC=CC=C2)[C@]3(CNCCO3)[H].S(C)(=O)(=O)O

Synonyms:

(2S)-2-[(S)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine methanesulfonate
2-[(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate
Davedax
Edronax
Fce 20124
Morpholine, 2-[(2-ethoxyphenoxy)phenylmethyl]-, (R*,R*)-(±)-, methanesulfonate
Morpholine, 2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel-, methanesulfonate
Morpholine, 2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel-, methanesulfonate (1:1)
Pnu 155905E
Pnu 155950E
Reboxetine mesilate
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