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CAS 98819-76-2

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Esreboxetine

Description:
Esreboxetine is a chemical compound classified as a selective norepinephrine reuptake inhibitor (NRI), primarily investigated for its potential use in treating major depressive disorder and attention deficit hyperactivity disorder (ADHD). It is characterized by its ability to enhance norepinephrine levels in the synaptic cleft by inhibiting its reabsorption into presynaptic neurons, which may contribute to its antidepressant effects. The molecular structure of esreboxetine includes a piperidine ring, which is common in many pharmacologically active compounds. Its pharmacokinetic profile suggests that it has a moderate half-life, allowing for once-daily dosing in clinical settings. Additionally, esreboxetine has been studied for its side effect profile, which may include insomnia, dry mouth, and increased heart rate, although it is generally well-tolerated. As research continues, the full therapeutic potential and safety profile of esreboxetine are still being evaluated, making it an interesting subject in the field of psychopharmacology.
Formula:C19H23NO3
InChI:InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19-/m0/s1
InChI key:InChIKey=CBQGYUDMJHNJBX-OALUTQOASA-N
SMILES:[C@H](OC1=C(OCC)C=CC=C1)(C2=CC=CC=C2)[C@@]3(CNCCO3)[H]
Synonyms:
  • (2S)-2-[(S)-(2-Ethoxyphenoxy)phenylmethyl]morpholine
  • (S,S)-(+)-Reboxetine
  • Morpholine, 2-[(2-ethoxyphenoxy)phenylmethyl]-, [S-(R*,R*)]-
  • Morpholine, 2-[(S)-(2-ethoxyphenoxy)phenylmethyl]-, (2S)-
Found 6 products.