CAS 98966-17-7

N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide

Description:

N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide, with the CAS number 98966-17-7, is a chemical compound that belongs to the class of acetamides. This substance features a complex structure characterized by the presence of multiple functional groups, including acetylamino and hydroxy groups, which contribute to its potential biological activity. The compound is likely to exhibit properties such as solubility in organic solvents and moderate solubility in water, influenced by its polar functional groups. Its molecular structure suggests potential applications in pharmaceuticals, particularly in the development of analgesics or anti-inflammatory agents, due to the presence of phenolic and amide functionalities. Additionally, the compound may exhibit antioxidant properties, making it of interest in various biochemical studies. As with many organic compounds, its stability, reactivity, and interactions with other substances would depend on environmental conditions such as pH and temperature. Safety and handling precautions should be observed, as with any chemical substance, to mitigate risks associated with exposure.

Formula: C₁₆H₁₆N₂O₄

InChI: InChI=1S/C16H16N2O4/c1-10(19)17-12-3-8-16(22)15(9-12)18(11(2)20)13-4-6-14(21)7-5-13/h3-9,21-22H,1-2H3,(H,17,19)

InChI key: InChIKey=NQLVUMFRDUPEJZ-UHFFFAOYSA-N

SMILES: N(C(C)=O)(C1=CC(NC(C)=O)=CC=C1O)C2=CC=C(O)C=C2

Synonyms:

• Acetamide, N-[5-(acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)-
• N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide
• Acetaminophen Impurity 21
• N-(5-acetamido-2-hydroxyphenyl)-N-(4-hydroxyphenyl)acetamide
• N-(5-ACETAMIDO-2-HYDROXYPHENYL)-N-(4-HYDROXYPHENYL)ACETAMIDE (ACETAMINOPHEN C-N DIMER)
• Acetaminophen Dimer Impurity
• Paracetamol Impurity 7
• Acetaminophen Impurity 19

Acetaminophen Impurity 8

CAS: 98966-17-7

Formula: C₁₆H₁₆N₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 300.31

Ref: 4Z-A-0231

N-​[5-​(Acetylamino)​-​2-​hydroxyphenyl]​-​N-​(4-​hydroxyphenyl)​acetamide

Controlled Product

CAS: 98966-17-7

Impurity Acetaminophen Impurity B
Applications N-​[5-​(Acetylamino)​-​2-​hydroxyphenyl]​-​N-​(4-​hydroxyphenyl)​acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-​[5-​(Acetylamino)​-​2-​hydroxyphenyl]​-​N-​(4-​hydroxyphenyl)​acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.
References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)

Formula: C₁₆H₁₆N₂O₄

Color and Shape: Neat

Molecular weight: 300.31

Ref: TR-A161245

Acetaminophen Impurity 8

CAS: 98966-17-7

Formula: C₁₆H₁₆N₂O₄

Molecular weight: 300.31

Ref: ST-EA-CP-A7004