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CAS 98983-40-5

:

9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one

Description:
9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one, commonly referred to as a nucleoside analog, is characterized by its structural features that include a purine base and a modified sugar moiety. The presence of a fluorine atom at the 2-position of the deoxyribose sugar enhances its stability and bioactivity, making it of interest in medicinal chemistry, particularly in antiviral and anticancer research. This compound exhibits properties typical of nucleosides, such as the ability to participate in nucleic acid synthesis and interactions with nucleic acid polymerases. Its purine base structure allows it to mimic natural nucleosides, potentially interfering with viral replication or cellular processes. The compound's solubility, stability, and reactivity are influenced by the presence of the fluorine atom, which can alter hydrogen bonding and steric interactions. Overall, this substance represents a significant area of study for developing therapeutic agents targeting various diseases, including viral infections and cancer.
Formula:C10H11FN4O4
InChI:InChI=1/C10H11FN4O4/c11-5-7(17)4(1-16)19-10(5)15-3-14-6-8(15)12-2-13-9(6)18/h2-5,7,10,16-17H,1H2,(H,12,13,18)/t4-,5+,7-,10-/m1/s1
Synonyms:
  • 6H-purin-6-one, 9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,9-dihydro-
  • 9-(2-deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthin
  • 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one
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