CAS 99011-02-6

Imiquimod

Description:

Imiquimod is an immune response modifier primarily used in dermatology for the treatment of certain skin conditions, including superficial basal cell carcinoma, actinic keratosis, and genital warts. It is classified as a topical agent and functions by stimulating the immune system, particularly enhancing the activity of immune cells such as macrophages and T-cells. Chemically, Imiquimod is a synthetic compound with a unique structure that includes a fused imidazoquinoline ring system. It is known for its ability to induce the production of cytokines, which play a crucial role in the immune response. Imiquimod is typically formulated as a cream for topical application, and its pharmacological effects are attributed to its ability to activate toll-like receptors, particularly TLR7, leading to an antiviral and antitumor response. The substance is generally well-tolerated, although local skin reactions may occur. Its mechanism of action and therapeutic applications make it a significant agent in the field of immunotherapy and dermatological treatments.

Formula: C₁₄H₁₆N₄

InChI: InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)

InChI key: InChIKey=DOUYETYNHWVLEO-UHFFFAOYSA-N

SMILES: C(C(C)C)N1C=2C=3C(N=C(N)C2N=C1)=CC=CC3

Synonyms:

• 1-(2-Methylpropyl)-1H-Imidazo[4,5-C]Quinolin-4-Amine
• 1-(2-Methylpropyl)imidazo[4,5-c]quinolin-4-amine
• 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
• 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-ylamine
• 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-
• 4-Amino-1-Isobutyl-1H-Imidazo[4,5-C]Quinoline
• Aldara
• Beselna
• Keravort
• R 837
• S 26308
• Tmx 101
• Zartra
• Zyclara

Imiquimod

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 240.31

Ref: 3B-I0747

Imiquimod, 99%

CAS: 99011-02-6

Imiquimod is a caspase 3 activator which acts as an immunomodulator and displays antiviral and anti-tumor activity. It is a patient-applied cream used for the treatment of genital warts and basal cell carcinoma. It is also used to cure actinic keratosis on the face and scalp. It belongs to a group o

Formula: C₁₄H₁₆N₄

Purity: 99%

Molecular weight: 240.31

Ref: 02-J63990

Imiquimod

CAS: 99011-02-6

Drugs primarily affecting the central nervous system, not elsewhere specified or included

Formula: C₁₄H₁₆N₄

Color and Shape: White Off-White Powder

Molecular weight: 240.1375

Ref: 45-1338313

1-(2-Methylpropyl)-1H-imidazo[4,5-C]quinolin-4-amine

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 240.3036

Ref: IN-DA00350O

Imiquimod

CAS: 99011-02-6

Imiquimod

Formula: C₁₄H₁₆N₄

Purity: ≥98%

Molecular weight: 240.3

Ref: 54-BUP16075

Imiquimod

CAS: 99011-02-6

Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.

Formula: C₁₄H₁₆N₄

Purity: 99.62% - >99.99%

Color and Shape: White Solid

Molecular weight: 240.30

Ref: TM-T0134

Imiquimod

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Color and Shape: White To Off-White Solid

Molecular weight: 240.31

Ref: 4Z-I-347

Imiquimod

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 240.31

Ref: 7W-GP9049

Imiquimod

Controlled Product

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Color and Shape: White To Off-White

Molecular weight: 240.30

Ref: 86-MM1158.00

Imiquimod (Standard)

CAS: 99011-02-6

Imiquimod (Standard) is the standard substance of Imiquimod, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models.

Formula: C₁₄H₁₆N₄

Molecular weight: 240.30

Ref: TM-TMSM-1360

Imiquimod

Controlled Product

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Color and Shape: Neat

Molecular weight: 240.30

Ref: 04-C14286100

Imiquimod

CAS: 99011-02-6

1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine

Formula: C₁₄H₁₆N₄

Purity: 98%

Molecular weight: 240.3

Ref: IN-DG23347

Imiquimod

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Molecular weight: 240.31

Ref: ST-EA-CP-I41003

Imiquimod

Controlled Product

CAS: 99011-02-6

Applications An immune response modifier. It stimulates the production of interferon-a.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998)

Formula: C₁₄H₁₆N₄

Color and Shape: Neat

Molecular weight: 240.3

Ref: TR-I475000

Imiquimod - Bio-X ™

CAS: 99011-02-6

Imiquimod is a toll-like receptor 7 agonist drug that is used for the treatment of genital warts, basal cell carcinoma and condyloma acuminata. This drug works by relieving and controlling wart production. Studies in mice have shown that this drug may induce cytokines such as interleukins. Imiquimod helps to increase apoptosis of diseased tissues and an infiltration of lymphocytes into tumor lesions.

Formula: C₁₄H₁₆N₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 240.3 g/mol

Ref: 3D-BI164576

Imiquimod

CAS: 99011-02-6

Caspase-3 activator; induces apoptosis; anti-angiogenic

Formula: C₁₄H₁₆N₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 240.3 g/mol

Ref: 3D-FI24563

4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 240.31

Ref: 10-F386709

Imiquimod-d6

Controlled Product

CAS: 99011-02-6

Formula: C₁₄D₆H₁₀N₄

Color and Shape: Neat

Molecular weight: 246.341

Ref: TR-I475002

Imiquimod for cell culture, 98%, Endotoxin (BET) 1EU/mg

CAS: 99011-02-6

Formula: C₁₄H₁₆N₄

Purity: min.98%

Color and Shape: White to Off-white, Powder

Molecular weight: 240.30

Ref: SR-75054