CAS 99140-25-7

Formula: C18H20N4O4

InChI: InChI=1S/C18H20N4O4/c1-21(2)9-3-8-19-14-6-7-15(22(25)26)17-16(14)18(24)12-10-11(23)4-5-13(12)20-17/h4-7,10,19,23H,3,8-9H2,1-2H3,(H,20,24)

InChI key: VNSZLRBNUNIGRI-UHFFFAOYSA-N

SMILES: CN(C)CCCNC1=C2C(=C(C=C1)[N+](=O)[O-])NC3=C(C2=O)C=C(C=C3)O

Topoisomerase II inhibitor 3

CAS: 99140-25-7

Acridone-based Topoisomerase II inhibitor 3 targets topo IIα/β (IC50: 0.17μM α, 0.23μM β), causes DNA damage, and induces apoptosis.

Formula: C₁₈H₂₀N₄O₄

Color and Shape: Solid

Molecular weight: 356.38

Ref: TM-T61283