CAS 99464-64-9

Ampiroxicam

Description:

Ampiroxicam is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the oxicam class of compounds. It is primarily characterized by its analgesic, anti-inflammatory, and antipyretic properties, making it useful in the management of pain and inflammation associated with various conditions, such as arthritis. The chemical structure of ampiroxicam features a pyridine ring and a 2-oxopyrrolidine moiety, contributing to its pharmacological activity. It functions by inhibiting cyclooxygenase (COX) enzymes, which play a crucial role in the biosynthesis of prostaglandins, mediators of inflammation and pain. Ampiroxicam is typically administered orally and exhibits a relatively long half-life, allowing for less frequent dosing. However, like other NSAIDs, it may be associated with gastrointestinal side effects, cardiovascular risks, and renal impairment, necessitating careful consideration of its use in patients with pre-existing conditions. Overall, ampiroxicam represents a valuable option in the therapeutic arsenal for managing inflammatory and painful conditions.

Formula: C₂₀H₂₁N₃O₇S

InChI: InChI=1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24)

InChI key: InChIKey=LSNWBKACGXCGAJ-UHFFFAOYSA-N

SMILES: O(C(OC(OCC)=O)C)C=1C=2C(S(=O)(=O)N(C)C1C(NC3=CC=CC=N3)=O)=CC=CC2

Synonyms:

• (±)-4-(1-Hydroxyethoxy)-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide ethyl carbonate (ester) 1,1-dioxide
• 2H-1,2-Benzothiazine, carbonic acid deriv.
• 99464-64-9
• Carbonic acid, ethyl 1-[[2-methyl-1,1-dioxido-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester
• Carbonic acid, ethyl 1-[[2-methyl-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester, S,S-dioxide
• Cp 65703
• Ethyl 1-{[2-methyl-1,1-dioxido-3-(pyridin-2-ylcarbamoyl)-2H-1,2-benzothiazin-4-yl]oxy}ethyl carbonate
• Flucam
• Nasil
• Ampiroxicam

Ampiroxicam

CAS: 99464-64-9

Formula: C₂₀H₂₁N₃O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 447.4616

Ref: IN-DA019FUX

Ampiroxicam

CAS: 99464-64-9

Ampiroxicam

Purity: ≥95%

Molecular weight: 447.46g/mol

Ref: 54-BUP10220

Ampiroxicam

CAS: 99464-64-9

Formula: C₂₀H₂₁N₃O₇S

Molecular weight: 447.46

Ref: 7W-GP2689

Ampiroxicam

CAS: 99464-64-9

Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.

Formula: C₂₀H₂₁N₃O₇S

Purity: 97.27% - 99.2%

Color and Shape: Powder

Molecular weight: 447.46

Ref: TM-T6387

Ampiroxicam

Controlled Product

CAS: 99464-64-9

Applications Prodrug of Piroxicam. Anti-inflammatory.
References Kurita, K., et al.: Oral. Ther. Pharmacol., 10, 138 (1991), Chen, M., et al.: Pharm. Res., 18, 1645 (2001), Davis, A., et al.: Curr. Opin. Chem. Biol., 8, 378 (2004), Votano, J., et al.: J. Med. Chem., 49, 7169 (2006),

Formula: C₂₀H₂₁N₃O₇S

Color and Shape: Neat

Molecular weight: 447.46

Ref: TR-A634350

Ampiroxicam

CAS: 99464-64-9

Cyclooxygenase inhibitor; NSAID drug

Formula: C₂₀H₂₁N₃O₇S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 447.46 g/mol

Ref: 3D-FA17891

Ampiroxicam - Bio-X ™

CAS: 99464-64-9

Ampiroxicam is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation for various conditions. This drug inhibits the enzyme cyclooxygenase which in turn inhibits prostaglandin synthesis resulting in a reduction of inflammation and pain.

Formula: C₂₀H₂₁N₃O₇S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 447.46 g/mol

Ref: 3D-BA164172