CAS 99464-64-9: Ampiroxicam
Description:Ampiroxicam is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the oxicam class of compounds. It is primarily characterized by its analgesic, anti-inflammatory, and antipyretic properties, making it useful in the management of pain and inflammation associated with various conditions, such as arthritis. The chemical structure of ampiroxicam features a pyridine ring and a 2-oxopyrrolidine moiety, contributing to its pharmacological activity. It functions by inhibiting cyclooxygenase (COX) enzymes, which play a crucial role in the biosynthesis of prostaglandins, mediators of inflammation and pain. Ampiroxicam is typically administered orally and exhibits a relatively long half-life, allowing for less frequent dosing. However, like other NSAIDs, it may be associated with gastrointestinal side effects, cardiovascular risks, and renal impairment, necessitating careful consideration of its use in patients with pre-existing conditions. Overall, ampiroxicam represents a valuable option in the therapeutic arsenal for managing inflammatory and painful conditions.
Formula:C20H21N3O7S
InChI:InChI=1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24)
InChI key:InChIKey=LSNWBKACGXCGAJ-UHFFFAOYSA-N
SMILES:O=C(OCC)OC(OC=1C=2C=CC=CC2S(=O)(=O)N(C1C(=O)NC3=NC=CC=C3)C)C
- Synonyms:
- (±)-4-(1-Hydroxyethoxy)-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide ethyl carbonate (ester) 1,1-dioxide
- 2H-1,2-Benzothiazine, carbonic acid deriv.
- 99464-64-9
- Carbonic acid, ethyl 1-[[2-methyl-1,1-dioxido-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester
- Carbonic acid, ethyl 1-[[2-methyl-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester, S,S-dioxide
- Cp 65703
- Ethyl 1-{[2-methyl-1,1-dioxido-3-(pyridin-2-ylcarbamoyl)-2H-1,2-benzothiazin-4-yl]oxy}ethyl carbonate
- Flucam
- Nasil
- Ampiroxicam
- See more synonyms
