CAS 99464-64-9
:Ampiroxicam
Description:
Ampiroxicam is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the oxicam class of compounds. It is primarily characterized by its analgesic, anti-inflammatory, and antipyretic properties, making it useful in the management of pain and inflammation associated with various conditions, such as arthritis. The chemical structure of ampiroxicam features a pyridine ring and a 2-oxopyrrolidine moiety, contributing to its pharmacological activity. It functions by inhibiting cyclooxygenase (COX) enzymes, which play a crucial role in the biosynthesis of prostaglandins, mediators of inflammation and pain. Ampiroxicam is typically administered orally and exhibits a relatively long half-life, allowing for less frequent dosing. However, like other NSAIDs, it may be associated with gastrointestinal side effects, cardiovascular risks, and renal impairment, necessitating careful consideration of its use in patients with pre-existing conditions. Overall, ampiroxicam represents a valuable option in the therapeutic arsenal for managing inflammatory and painful conditions.
Formula:C20H21N3O7S
InChI:InChI=1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24)
InChI key:InChIKey=LSNWBKACGXCGAJ-UHFFFAOYSA-N
SMILES:O(C(OC(OCC)=O)C)C=1C=2C(S(=O)(=O)N(C)C1C(NC3=CC=CC=N3)=O)=CC=CC2
Synonyms:- (±)-4-(1-Hydroxyethoxy)-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide ethyl carbonate (ester) 1,1-dioxide
- 2H-1,2-Benzothiazine, carbonic acid deriv.
- 99464-64-9
- Carbonic acid, ethyl 1-[[2-methyl-1,1-dioxido-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester
- Carbonic acid, ethyl 1-[[2-methyl-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester, S,S-dioxide
- Cp 65703
- Ethyl 1-{[2-methyl-1,1-dioxido-3-(pyridin-2-ylcarbamoyl)-2H-1,2-benzothiazin-4-yl]oxy}ethyl carbonate
- Flucam
- Nasil
- Ampiroxicam
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Ampiroxicam
CAS:Controlled ProductApplications Prodrug of Piroxicam. Anti-inflammatory.
References Kurita, K., et al.: Oral. Ther. Pharmacol., 10, 138 (1991), Chen, M., et al.: Pharm. Res., 18, 1645 (2001), Davis, A., et al.: Curr. Opin. Chem. Biol., 8, 378 (2004), Votano, J., et al.: J. Med. Chem., 49, 7169 (2006),Formula:C20H21N3O7SColor and Shape:NeatMolecular weight:447.46Ampiroxicam
CAS:Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.Formula:C20H21N3O7SPurity:97.27% - 99.2%Color and Shape:SolidMolecular weight:447.462Ampiroxicam
CAS:Cyclooxygenase inhibitor; NSAID drugFormula:C20H21N3O7SPurity:Min. 95%Color and Shape:PowderMolecular weight:447.46 g/molAmpiroxicam
CAS:Ethyl (1-((2-methyl-1,1-dioxido-3-(pyridin-2-ylcarbamoyl)-2H-benzo[e][1,2]thiazin-4-yl)oxy)ethyl) carbonateFormula:C20H21N3O7SPurity:98%Molecular weight:447.46Ampiroxicam - Bio-X ™
CAS:Ampiroxicam is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation for various conditions. This drug inhibits the enzyme cyclooxygenase which in turn inhibits prostaglandin synthesis resulting in a reduction of inflammation and pain.Formula:C20H21N3O7SPurity:Min. 95%Color and Shape:PowderMolecular weight:447.46 g/mol
