CAS 99614-02-5
:Ondansetron
Description:
Ondansetron is a selective serotonin 5-HT3 receptor antagonist primarily used as an antiemetic to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. Its chemical formula is C18H19N3O, and it features a complex structure that includes a benzamide moiety. Ondansetron is known for its high affinity for the 5-HT3 receptor, which plays a crucial role in the vomiting reflex. The substance is typically administered orally or intravenously and is well-absorbed in the gastrointestinal tract. Ondansetron is characterized by its relatively low solubility in water, which can affect its formulation in pharmaceutical preparations. It is generally well-tolerated, with side effects that may include headache, constipation, and dizziness. The drug is metabolized primarily in the liver, and its elimination half-life allows for flexible dosing regimens. Due to its effectiveness and safety profile, ondansetron has become a standard treatment in managing chemotherapy-induced nausea and vomiting.
Formula:C18H19N3O
InChI:InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3
InChI key:InChIKey=FELGMEQIXOGIFQ-UHFFFAOYSA-N
SMILES:O=C1C=2C=3C(N(C)C2CCC1CN4C(C)=NC=C4)=CC=CC3
Synonyms:- gr38032
- 1,2,3,4-tetrahydro-9-methyl-3-(2-methyl-1h-imidazol-1-ylmethyl)carbazol-4-one
- 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
- 9-Methyl-3-[(2-methyl-1H-imidazolyl)-methyl]-1,2,3,9-tetrahydro-4H-carbazole-4-one
- 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]- (9CI)
- GR 38032X
- 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one
- 3-[(2-methylimidazol-1-yl)methyl]-1,2,3,4a,9,9a-hexahydrocarbazol-4-one
- 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1h-imidazol-1-yl)methyl)-4h-carbazo
- gr38032x
- OndansetronBase99%
- 1,2,3,4-TETRAHYDRO-9-METHYL-3-(2-METHYL-1H-IMIDAZOLE-1-YLMETHYL)CARBAZOL-4-ONE
- GR 38032
- Ondansetron
- See more synonyms
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Ondansetron
CAS:Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoiFormula:C18H19N3OColor and Shape:White Off-White PowderMolecular weight:293.15281Ondansetron-13C-d3
CAS:Formula:C1713CH16D3N3OColor and Shape:White To Off-White SolidMolecular weight:297.38Ondansetron-d5(methylimidazole-d5)
CAS:Purity:97 atom % DColor and Shape:White Solid.Molecular weight:298.40Ondansetron
CAS:Controlled ProductApplications Ondansetron is a specific serotonin (5-HT3) receptor antagonist. Antiemetic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)Formula:C18H19N3OColor and Shape:NeatMolecular weight:293.369-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one
CAS:9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-oneFormula:C18H19N3OPurity:99%Molecular weight:293.36Ondansetron
CAS:Ondansetron (GR 38032) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.Formula:C18H19N3OPurity:99.92%Color and Shape:White To Yellow CrystalsMolecular weight:293.363Ondansetron
CAS:Serotonin receptor 5-HT3 antagonist
Formula:C18H19N3OPurity:Min. 95%Color and Shape:PowderMolecular weight:293.36 g/mol
