CAS 99785-51-0
:3'-bromo-3'-deoxythymidine
Description:
3'-Bromo-3'-deoxythymidine, also known as BrdU (Bromodeoxyuridine), is a synthetic nucleoside analog of thymidine, where a bromine atom is substituted at the 3' position of the sugar moiety. This compound is characterized by its ability to incorporate into DNA during replication, thereby serving as a useful tool in molecular biology and cancer research for studying cell proliferation. It is often used in assays to measure cell division and DNA synthesis, as it can be detected using specific antibodies. The presence of the bromine atom enhances its photochemical properties, making it suitable for various labeling techniques. In terms of solubility, BrdU is typically soluble in water and organic solvents, which facilitates its use in biological experiments. However, it is important to handle this compound with care, as it can be cytotoxic at high concentrations. Overall, 3'-bromo-3'-deoxythymidine is a valuable compound in research settings, particularly in studies involving DNA synthesis and cellular dynamics.
Formula:C10H13BrN2O4
InChI:InChI=1/C10H13BrN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1
InChI key:VSYTWOCFTNWUQF-XLPZGREQSA-N
SMILES:CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)Br
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3'-Bromo-3'-deoxythymidine
CAS:3'-Bromo-3'-deoxythymidine is a Nucleoside Derivative - Halo-nucleoside, 2',3'-Dideoxy nucleoside.Formula:C10H13BrN2O4Color and Shape:SolidMolecular weight:305.13
