Amino Acid Derivatives

<p>Lauroyl lysine (N6-Lauroyl-L-lysine) functions as skin and hair conditioning agents and as surfactants-cleansing agents in personal care products.</p>

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<p>Gamma-L-glutamyl-alpha-naphthylamide is an enzyme that catalyzes the conversion of L-glutamic acid to L-glutamate. It is expressed in red blood cells, human liver, and human serum. Gamma-L-glutamyl-alpha-naphthylamide has been shown to have various specificities for different tissues and isoenzymes. This enzyme also has immunoassay procedures that are used to detect it in tissues or cells. These assays use monoclonal antibodies or solubilized gamma-L-glutamyl-alpha-naphthylamide molecules as detection agents.</p>

<p>Boc-His(Trt)-OH is a chemical compound that has been used in the laboratory to study uptake and binding of compounds. It is stable in complex with albumin, which has led to its use as a model system for studying hepatic steatosis. This chemical can be synthesized by solid-phase synthesis with trifluoroacetic acid and polypeptide synthesis. FT-IR spectroscopy has been used to characterize Boc-His(Trt)-OH, revealing its chemical diversity.</p>

<p>L-Threonine derivative-1 is acetylsalicylic acid-L-threonine ester with potential analgesic activity.</p>

<p>Ala-Ala-bNA is a substrate for dipeptidyl aminopeptidase I (cathepsin C)</p>

<p>N-Boc-glycine is a chemical compound used in the synthesis of cyclic peptides. N-Boc-glycine is synthesized by the reaction of glycine with methanol and hydrochloric acid in the presence of an activated form of carbon monoxide. The pharmacokinetic properties of N-Boc-glycine are similar to those for human immunoglobulin, and it can be used as a reference compound for preparative high performance liquid chromatography (HPLC). It has been shown that the nitrogen atoms in N-Boc-glycine are chemically stable, which makes it suitable for asymmetric synthesis. N-Boc-glycine also has potent antagonist effects on biochemical properties such as calcium channel blockade, inhibition of platelet aggregation, and inhibition of neutrophil chemotaxis.</p>

<p>S-Fcme activates multidrug resistance transporter by boosting ATPase activity and competing for drug binding.</p>

<p>S-Benzylglutathione acts as a competitive inhibitor of glutathionase and undergoes conversion by rat kidney microsomes into its cysteine derivatives.</p>

<p>S-(p-Nitrobenzyl)glutathione acts as a competitive inhibitor of glutathionase.</p>

<p>3,3',5'-Triiodo-D-thyronine is a thyroid hormone that is used in the treatment of hypothyroidism. It is administered by injection or by mouth. 3,3',5'-Triiodo-D-thyronine is an insoluble drug, which means it cannot be dissolved in water. This drug can be injected into the body or taken as a pill. 3,3',5'-Triiodo-D-thyronine has been shown to increase metabolic rate and may also inhibit the growth of certain types of tumors. 3,3',5'-Triiodo-D-thyronine has been used in diagnostic procedures such as iontophoresis and implanting devices to treat prostate cancer. This medication can also be used for cosmetic purposes such as skin rejuvenation and hair loss prevention. 3,3',5'-Triiodo-D-thyronine has two structural isomers: levothyroxine and</p>

<p>Cys-Gly-3M3SH is a cationic antimicrobial peptide that has been shown to be effective against Staphylococcus aureus. Cys-Gly-3M3SH binds to the bacterial enzyme urease, which is responsible for converting urea into ammonia and carbon dioxide. The binding of this peptide prevents the hydrolysis of urea, leading to cell death by disruption of the proton motive force. Cys-Gly-3M3SH is also biotransformed by bacteria in humans and can be used as a probe for transport studies in vitro. It can also be used as a molecular probe for structural biology research, such as protein crystallization and electron microscopy studies.</p>

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<p>L-Tryptophan methyl ester hydrochloride is an allylation product of L-tryptophan, which is a precursor to serotonin and melatonin. It is used in the synthesis of benzodiazepine receptor ligands and has serotonergic activity. L-Tryptophan methyl ester hydrochloride can be synthesized from L-tryptophan by amination reaction with methylamine and formaldehyde in the presence of a base. This chemical compound was also shown to have antitumour activity against MDA-MB231 breast cancer cells, which may be due to its ability to inhibit cell proliferation.</p>

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<p>2-Amino-5-methyl-5-hexenoic acid ((S)-2-Amino-5-methylhex-5-enoic acid) acts as a methionine analog, competing with methionine and thereby hindering cell growth. This compound inhibits protein synthesis in Salmonella typhimurium TA1535 and Escherichia coli K-12 without affecting the synthesis of DNA or RNA.</p>

<p>Fmoc-NH-PEG6-alcohol, a cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs) [1].</p>

<p>Phospho-L-arginine is a derivative of arginine.</p>

<p>D-allo-Threoninol is a conformational analogue of threonine. It has been shown to inhibit the growth of Escherichia coli, Bacillus subtilis, and Staphylococcus aureus in vitro. D-allo-Threoninol binds to the enzyme methionine adenosyltransferase (MAT) by forming hydrogen bonds with its amino acid side chains. This binding prevents the formation of the MAT-coenzyme A complex, inhibiting protein synthesis and cell division.</p>