EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
Found 572 products of "EGFR"
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Canertinib
CAS:Formula:C24H25ClFN5O3Purity:>98.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:485.94CL-387785
CAS:Formula:C18H13BrN4OPurity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:381.23(3S,4S)-PF-06459988
CAS:<p>(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.</p>Formula:C19H22ClN7O3Color and Shape:SolidMolecular weight:431.88BMS-599626
CAS:Formula:C27H27FN8O3Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:530.56Erlotinib-d6
CAS:<p>Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .</p>Formula:C22H23N3O4Purity:98%Color and Shape:SolidMolecular weight:399.47AG 1478 Hydrochloride
CAS:Formula:C16H14ClN3O2·HClPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:352.22EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Color and Shape:Lyophilized PowderMolecular weight:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.Hypericin
CAS:Formula:C30H16O8Purity:>95.0%(HPLC)Color and Shape:Black powder to crystalMolecular weight:504.45Rociletinib hydrobromide
CAS:<p>Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).</p>Formula:C27H29BrF3N7O3Purity:98%Color and Shape:SolidMolecular weight:636.46Osimertinib dimesylate
CAS:<p>Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).</p>Formula:C30H41N7O8S2Purity:98%Color and Shape:SolidMolecular weight:691.82Mavelertinib
CAS:<p>Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.</p>Formula:C18H22FN9O2Purity:99.89%Color and Shape:SolidMolecular weight:415.42Tyrphostin AG 1478
CAS:Formula:C16H14ClN3O2Purity:>98.0%(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:315.76WHI-P154
CAS:Formula:C16H14BrN3O3Purity:>98.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:376.21Tucatinib hemiethanolate
CAS:<p>Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.</p>Formula:C54H54N16O5Purity:99.76%Color and Shape:SolidMolecular weight:1007.11Mubritinib
CAS:Formula:C25H23F3N4O2Purity:>98.0%(HPLC)Color and Shape:White to Gray to Brown powder to crystalMolecular weight:468.48AEE 788
CAS:Formula:C27H32N6Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:440.60BI-4142
CAS:<p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>Formula:C28H27N9O2Purity:97.21% - 98.09%Color and Shape:SolidMolecular weight:521.57Rilematovir
CAS:<p>Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.</p>Formula:C21H20ClF3N4O3SPurity:99.82%Color and Shape:SolidMolecular weight:500.92AV-412 free base
CAS:<p>AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).</p>Formula:C27H28ClFN6OColor and Shape:SolidMolecular weight:507PD 158780
CAS:Formula:C14H12BrN5Purity:>97.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:330.19
