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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • CymitQuimica logo
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    Zanidatamab

    CAS:
    <p>Zanidatamab (ZW25) is a bispecific, humanized monoclonal antibody that targets two distinct epitopes (ECD2 and ECD4) of the HER2 receptor, exhibiting anti-tumor</p>
    Color and Shape:Liquid

    Ref: TM-T76875

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    Anbenitamab

    CAS:
    <p>Anbenitamab (KN-026) is a bispecific HER2 antibody for metastatic breast cancer research, blocking HER2 pathways and mediating ADCC.</p>
    Color and Shape:Liquid

    Ref: TM-T76905

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    Becotatug

    CAS:
    <p>Becotatug (JMT-101) is an IgG1 antibody that targets EGFR and can be conjugated to Afatinib and Osimertinib, functioning as a synthetic antibody-drug conjugate</p>
    Purity:95% - 95%
    Color and Shape:Liquid

    Ref: TM-T80574

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    Depatuxizumab

    CAS:
    <p>Depatuxizumab is a humanised monoclonal antibody targeting EGFR with blood-brain barrier (BBB) permeability, inhibit tumor growth,GBM,SCCHN.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T78326

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    Futuximab

    CAS:
    <p>Futuximab, a chimeric monoclonal antibody, targets distinct epitopes on the epidermal growth factor receptor (EGFR), exhibiting antineoplastic activity [1].</p>
    Purity:95% - 95%
    Color and Shape:Liquid

    Ref: TM-T77015

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    Izalontamab

    CAS:
    <p>Izalontamab (SI-B001) is a bispecific EGFR/HER3 monoclonal antibody that binds to both EGFR×EGFR homodimers and EGFR×HER3 heterodimers.</p>
    Purity:95%+ - 95%+
    Color and Shape:Liquid

    Ref: TM-T77047

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    Imgatuzumab

    CAS:
    <p>Imgatuzumab (RG 7160) is a humanized anti-EGFR monoclonal antibody and immunomodulator for cancer research.</p>
    Color and Shape:Liquid
    Molecular weight:145.0 (kDa)

    Ref: TM-T76811

  • lavendustin A
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    lavendustin A

    CAS:
    <p>lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.</p>
    Formula:C21H19NO6
    Purity:98%
    Color and Shape:Off-White Solid
    Molecular weight:381.38

    Ref: TM-T4183

  • ZM323881 hydrochloride
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    ZM323881 hydrochloride

    CAS:
    <p>ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.</p>
    Formula:C22H19ClFN3O2
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:411.86

    Ref: TM-T1991

  • Icotinib
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    Icotinib

    CAS:
    <p>Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.</p>
    Formula:C22H21N3O4
    Purity:99.76% - 99.94%
    Color and Shape:Solid
    Molecular weight:391.42

    Ref: TM-T6153

  • IGF-1R modulator 1
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    IGF-1R modulator 1

    CAS:
    <p>IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), and 0.39 μM (TrkB). This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimer's disease.</p>
    Formula:C22H17N3O4
    Color and Shape:Solid
    Molecular weight:387.39

    Ref: TM-T88615

  • TAK-285
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    TAK-285

    CAS:
    <p>TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, &gt;10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.</p>
    Formula:C26H25ClF3N5O3
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:547.96

    Ref: TM-T6039

  • Icotinib Hydrochloride
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    Icotinib Hydrochloride

    CAS:
    <p>Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.</p>
    Formula:C22H22ClN3O4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:427.88

    Ref: TM-T2307

  • Limertinib
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    Limertinib

    CAS:
    <p>Limertinib (ASK120067) is a EGFR tyrosine kinase inhibitor targeting EGFR T790M, applicable for the study of non-small cell lung cancer.</p>
    Formula:C29H32ClN7O2
    Purity:97.44%
    Color and Shape:Solid
    Molecular weight:546.06

    Ref: TM-T35897

  • EGFR/HER2-IN-9
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    EGFR/HER2-IN-9

    CAS:
    <p>EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR</p>
    Formula:C25H25ClFN5O4
    Color and Shape:Solid
    Molecular weight:513.95

    Ref: TM-T72854

  • EGFR/C797S-IN-1
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    EGFR/C797S-IN-1

    CAS:
    <p>EGFR/C797S-IN-1: Potent EGFR-C797S inhibitor, IC50 of 0.128 µM, dose-dependent p-EGFR suppression, anti-tumor properties.</p>
    Formula:C28H30N4O3
    Color and Shape:Solid
    Molecular weight:470.56

    Ref: TM-T72788

  • EAI001
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    EAI001

    CAS:
    <p>EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.</p>
    Formula:C19H15N3O2S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:349.41

    Ref: TM-T61191

  • EGFR-IN-63
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    EGFR-IN-63

    CAS:
    <p>EGFR- IN-63 is an EGFR inhibitor with an IC50 value of 0.096 μM. EGFR- IN-63 exhibited anticancer effects on MCF-7 cells (IC50: 2.49 μM).</p>
    Formula:C20H12BrN5S
    Color and Shape:Solid
    Molecular weight:434.31

    Ref: TM-T62446

  • BIBX 1382 Dihydrochloride
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    BIBX 1382 Dihydrochloride

    CAS:
    <p>BIBX 1382 Dihydrochloride blocks Lassa/Ebola entry, aids in studying virus-host interactions, and hints at kinase targets for therapy.</p>
    Formula:C18H21Cl3FN7
    Color and Shape:Solid
    Molecular weight:460.76

    Ref: TM-T30443

  • (E/Z)-CP-724714
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    (E/Z)-CP-724714

    CAS:
    <p>(E/Z)-CP-724714, comprising racemic mixtures of (E)-CP-724714 and (Z)-CP-724714 isomers, is a potent, selective, and orally active inhibitor of ErbB2 (HER2)[1].</p>
    Formula:C27H27N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.54

    Ref: TM-T6046