EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
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Ligustroside
CAS:35897-92-8
Ligustroside mildly inhibits PGE2, has slight antioxidant and anti-inflammatory effects, and is moderately antiviral against …
Formula:
C25H32O12
Purity:
98%
Color and Shape:
Solid
Molecular weight:
524.51
Ref: TM-TN1871
| 5mg | 1,603.00 € | ||
| 1mL*10mM (DMSO) | 1,915.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
JAK 3 inhibitor IV
CAS:58753-54-1
JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, …
Formula:
C16H19NO
Purity:
98%
Color and Shape:
Solid
Molecular weight:
241.33
Ref: TM-T2460
| 5mg | 68.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | 315.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EGFR-IN-90
EGFR-IN-90 (compound 34), an orally active EGFR inhibitor, demonstrates potent activity against EGFRL858R/T790M/C797S with an …
Purity:
98%
Ref: TM-T82491
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EGFR-IN-79
EGFR-IN-79 (compound 21), an EGFR inhibitor, exhibits antitumor activity through ROS-independent apoptosis and EGFR/AKT/mTOR-mediated autophagy.
Formula:
C23H16ClN3O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
417.84
Ref: TM-T79293
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Matuzumab
CAS:339186-68-4
Matuzumab (EMD 72000) is a humanized monoclonal antibody targeting EGFR that can be used to …
Purity:
95%
Color and Shape:
Liquid
Molecular weight:
145.9 kDa
Ref: TM-T9922
| 1mg | 212.00 € | ||
| 5mg | 541.00 € | ||
| 10mg | 760.00 € | ||
| 25mg | 1,160.00 € | ||
| 50mg | 1,568.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EGFR mutant-IN-1
EGFR mutant-in-1, a 5-methylpyrimidopyridone, selectively inhibits EGFRL858R/T790M/C797S mutants with an IC50 of 27.5 nM, lessening …
Formula:
C34H39ClFN7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
632.17
Ref: TM-T11164
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WAY-270360
CAS:476633-98-4
WAY-270360 (N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide) is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.
Formula:
C22H19N3O3
Purity:
98.66%
Color and Shape:
Liquid
Molecular weight:
373.4
Ref: TM-T60064
| 1mg | 63.00 € | ||
| 5mg | 137.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 455.00 € | ||
| 100mg | 641.00 € | ||
| 500mg | 1,272.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Os30
Os30 is a potent fourth-generation EGFR inhibitor, specifically targeting the EGFRC797S-TK mutation with IC50 values …
Purity:
98%
Ref: TM-T81596
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Petosemtamab
CAS:2213450-26-9
Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor …
Purity:
> 95% - > 95%
Color and Shape:
Liquid
Molecular weight:
145.97 kDa
Ref: TM-T76890
| 1mg | 332.00 € | ||
| 5mg | 862.00 € | ||
| 10mg | 1,392.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Chamigrenal
CAS:19912-84-6
β-Chamigrenal: Anti-inflammatory, inhibits NO and PGE2 in macrophages, PAF antagonist (IC50=1.2x10^-4 M), weakly cytotoxic to …
Formula:
C15H22O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
218.33
Ref: TM-T3P2855
| 1mg | 88.00 € | ||
| 5mg | 350.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZ7550 hydrochloride
CAS:2309762-40-9
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R …
Formula:
C27H32ClN7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
522.04
Ref: TM-T13564L
| 1mg | 122.00 € | ||
| 5mg | 240.00 € | ||
| 10mg | 371.00 € | ||
| 25mg | 619.00 € | ||
| 50mg | 882.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Intetumumab
CAS:725735-28-4
Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for …
Color and Shape:
Liquid
Molecular weight:
145.6 (kDa)
Ref: TM-T76812
| 1mg | 246.00 € | ||
| 5mg | 742.00 € | ||
| 10mg | 1,260.00 € | ||
| 25mg | 1,829.00 € | ||
| 50mg | 2,501.00 € | ||
| 100mg | 3,406.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Lumretuzumab
CAS:1448327-63-6
Lumretuzumab (RG-7116) is a humanized anti-HER3 monoclonal antibody with antitumor activity.
Color and Shape:
Liquid
Ref: TM-T76818
| 1mg | 259.00 € | ||
| 5mg | 649.00 € | ||
| 10mg | 1,018.00 € | ||
| 25mg | 1,540.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,735.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SJF 1521
CAS:2230821-40-4
SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR …
Formula:
C57H61ClFN7O9S
Purity:
99.20%
Color and Shape:
Liquid
Molecular weight:
1074.65
Ref: TM-T36244
| 1mg | 571.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
1,5-Dihydroxyxanthone
CAS:14686-65-8
1,5-Dihydroxyxanthone inhibits EGFR-tyrosine kinase (IC50: 90.34 nM) and may block AChE/BChE.
Formula:
C13H8O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
228.203
Ref: TM-TN2504
| 5mg | 1,707.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cisapride hydrate
CAS:260779-88-2
Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of …
Formula:
C23H31ClFN3O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
483.97
Ref: TM-T22296
| 500mg | 552.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Depatuxizumab
CAS:1471999-69-5
Depatuxizumab, a brain-penetrant, humanized anti-EGFR monoclonal antibody, selectively inhibits the growth of mutant EGFRvIII and …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T78326
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MTX-241F
MTX-241F, a selective small molecule inhibitor, targets members of the EGFR and PI3 kinase families.
Formula:
C20H14ClFN6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
392.82
Ref: TM-T78877
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARRY-380 (analog )
CAS:937265-83-3
ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor.
Formula:
C29H27N7O4S
Purity:
98.22%
Color and Shape:
Solid
Molecular weight:
569.63
Ref: TM-T2518
| 1mg | 35.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 108.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 261.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BMS-599626
CAS:714971-09-2
BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 …
Formula:
C27H27FN8O3
Purity:
98.73%
Color and Shape:
Solid
Molecular weight:
530.55
Ref: TM-T2610
| 10mg | 530.00 € | ||
| 25mg | 1,205.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
