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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 618 products for "EGFR".

products per page.
  • Rociletinib

    CAS:
    Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic
    Formula:C27H28F3N7O3
    Purity:98.52% - 99.25%
    Color and Shape:Solid
    Molecular weight:555.5515
  • Allitinib

    CAS:
    Allitinib (AST-1306) (AST-1306) has anti-cancer activity,and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]
    Formula:C24H18ClFN4O2
    Purity:99.89% - 99.91%
    Color and Shape:Yellow Solid
    Molecular weight:448.877
  • Gefitinib

    CAS:
    Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations.
    Formula:C22H24ClFN4O3
    Purity:99.89% - >99.99%
    Color and Shape:White Solid
    Molecular weight:446.902
  • LCH-7749944

    CAS:
    LCH-7749944 suppresses human gastric cancer cell growth, induces apoptosis, and inhibits PAK4 with IC50 of 14.93 μM.
    Formula:C20H22N4O2
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:350.4143
  • Pyrotinib dimaleate

    CAS:
    Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor, respectively, for the treatment of HER2-positive breast cancer.Cost-effective and quality-assured.
    Formula:C40H39ClN6O11
    Purity:98.12% - 99.52%
    Color and Shape:Solid
    Molecular weight:815.224
  • Ref: IN-DA0039KT

    100g
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    250g
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    25mg
    27.00€
    100mg
    43.00€
    250mg
    55.00€
    1g
    105.00€
    5g
    262.00€
    50g
    586.00€
  • Intetumumab

    CAS:
    Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.
    Purity:97.6% (SDS-PAGE); 97.1% (SEC-HPLC) - 97.6% (SDS-PAGE); 97.1% (SEC-HPLC)
    Color and Shape:Transparent Liquid
    Molecular weight:145.56 kDa (Predicted)
  • AV-412

    CAS:
    AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).
    Formula:C41H44ClFN6O7S2
    Purity:99.85% - 99.92%
    Color and Shape:Solid
    Molecular weight:851.405
  • HyT36

    CAS:
    HyT36: hydrophobic tag that destabilizes fusion proteins & Her3 pseudokinase; treats cells with acute erht.
    Formula:C25H44ClNO3
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:442.075
  • Erlotinib

    CAS:
    Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
    Formula:C22H23N3O4
    Purity:98.19% - 99.98%
    Color and Shape:White Solid
    Molecular weight:393.4357
  • Erlotinib hydrochloride

    CAS:
    Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
    Formula:C22H24ClN3O4
    Purity:99.78% - 99.97%
    Color and Shape:Solid
    Molecular weight:429.897
  • Petosemtamab

    CAS:
    Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.
    Purity:> 95% - > 95%
    Color and Shape:Transparent Liquid
    Molecular weight:145.97 kDa (Predicted)
  • Gancotamab

    CAS:
    Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.
    Purity:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)
    Color and Shape:Transparent Liquid
    Molecular weight:25.79 kDa (Predicted)
  • Khellin

    CAS:
    Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.
    Formula:C14H12O5
    Purity:99.89% - 99.95%
    Color and Shape:Solid
    Molecular weight:260.2421
  • BLU-945

    CAS:
    BLU-945 is a reversible, potent, highly selective, and orally available epidermal growth factor receptor tyrosine kinase inhibitor (TKIs).Cost-effective and quality-assured.
    Formula:C28H37FN6O3S
    Purity:99.16% - 99.17%
    Color and Shape:Solid
    Molecular weight:556.695
  • O-Desmethyl gefitinib

    CAS:
    O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed by CYP2D6.
    Formula:C21H22ClFN4O3
    Purity:97.17%
    Color and Shape:White Solid
    Molecular weight:432.876
  • Lapatinib Ditosylate

    CAS:
    Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
    Formula:C43H42ClFN4O10S3
    Purity:99.41%
    Color and Shape:White Solid
    Molecular weight:925.461
  • Mevastatin

    CAS:
    Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.
    Formula:C23H34O5
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:390.51
  • Lapatinib ditosylate monohydrate

    CAS:
    Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.
    Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2O
    Purity:98% - 99.41%
    Color and Shape:White Solid
    Molecular weight:943.47
  • Barecetamab

    CAS:
    Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.
    Purity:97.1% (SDS-PAGE); 96.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 96.4% (SEC-HPLC)
    Color and Shape:Transparent Liquid
    Molecular weight:143.86 kDa (Predicted)