EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
Read more
Naluzotan hydrochloride
CAS:740873-82-9
Naluzotan hydrochloride, a hERG K+ blocker (IC50: 3800 nM) and potent 5-HT1A agonist (IC50: ~20 …
Formula:
C23H39ClN4O3S
Purity:
98.61%
Color and Shape:
Liquid
Molecular weight:
487.1
Ref: TM-T68113
| 1mg | 215.00 € | ||
| 5mg | 530.00 € | ||
| 10mg | 759.00 € | ||
| 25mg | 1,168.00 € | ||
| 50mg | 1,559.00 € | ||
| 100mg | 2,116.00 € | ||
| 500mg | 4,241.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
BMS-599626
CAS:714971-09-2
BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 …
Formula:
C27H27FN8O3
Purity:
98.73%
Color and Shape:
Solid
Molecular weight:
530.55
Ref: TM-T2610
| 10mg | 530.00 € | ||
| 25mg | 1,205.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
SJF 1521
CAS:2230821-40-4
SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR …
Formula:
C57H61ClFN7O9S
Purity:
99.20%
Color and Shape:
Liquid
Molecular weight:
1074.65
Ref: TM-T36244
| 1mg | 571.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Cetuximab MMAE
Cetuximab-MMAE, an antibody-drug conjugate (ADC), combines an EGFR-targeting antibody with Monomethyl auristatin E (MMAE) to …
Color and Shape:
Liquid
Molecular weight:
150 kDa
Ref: TM-T9901A-219
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Matuzumab
CAS:339186-68-4
Matuzumab (EMD 72000) is a humanized monoclonal antibody targeting EGFR that can be used to …
Purity:
95%
Color and Shape:
Liquid
Molecular weight:
145.9 kDa
Ref: TM-T9922
| 1mg | 212.00 € | ||
| 5mg | 541.00 € | ||
| 10mg | 760.00 € | ||
| 25mg | 1,160.00 € | ||
| 50mg | 1,568.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
EGFR-IN-124
EGFR-IN-124 (compound 10A) is an EGFR inhibitor with an IC50 value of 0.54 μM, utilized …
Ref: TM-T200720
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
EGFR-IN-127
EGFR-IN-127 is an ATP-competitive inhibitor targeting EGFR, with IC50 values of 136.3 nM for EGFRdel19 …
Ref: TM-T200430
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Ligustroside
CAS:35897-92-8
Ligustroside mildly inhibits PGE2, has slight antioxidant and anti-inflammatory effects, and is moderately antiviral against …
Formula:
C25H32O12
Purity:
98%
Color and Shape:
Solid
Molecular weight:
524.51
Ref: TM-TN1871
| 5mg | 1,603.00 € | ||
| 1mL*10mM (DMSO) | 1,915.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Depatuxizumab MMAF
Depatuxizumab-MMAF, an antibody-drug conjugate (ADC), comprises an EGFR-targeted antibody linked to McMMAF and is utilized …
Color and Shape:
Liquid
Molecular weight:
148.24 kDa
Ref: TM-T9901A-197
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Chamigrenal
CAS:19912-84-6
β-Chamigrenal: Anti-inflammatory, inhibits NO and PGE2 in macrophages, PAF antagonist (IC50=1.2x10^-4 M), weakly cytotoxic to …
Formula:
C15H22O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
218.33
Ref: TM-T3P2855
| 1mg | 88.00 € | ||
| 5mg | 350.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
DS06652923
DS06652923 is an orally active inhibitor targeting EGFR triple mutations. It exhibits growth-inhibitory effects on …
Ref: TM-T200714
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Astragaloside VI
CAS:84687-45-6
Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway.
Formula:
C47H78O19
Purity:
98%
Color and Shape:
Solid
Molecular weight:
947.122
Ref: TM-T13559
| 10mg | 562.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
JAK 3 inhibitor IV
CAS:58753-54-1
JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, …
Formula:
C16H19NO
Purity:
98%
Color and Shape:
Solid
Molecular weight:
241.33
Ref: TM-T2460
| 5mg | 68.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | 315.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Nezutatug
CAS:2673271-78-6
Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1].
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T81679
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
EGFR/CDK2-IN-3
EGFR/CDK2-IN-3 (compound 4b) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 …
Formula:
C30H20N6OS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
512.58
Ref: TM-T79728
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
EGFR mutant-IN-1
EGFR mutant-in-1, a 5-methylpyrimidopyridone, selectively inhibits EGFRL858R/T790M/C797S mutants with an IC50 of 27.5 nM, lessening …
Formula:
C34H39ClFN7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
632.17
Ref: TM-T11164
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Pimurutamab
CAS:2251771-76-1
Pimurutamab, a humanized IgG1-κ antibody, selectively targets the epidermal growth factor receptor (EGFR) and is …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80612
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
EGFR/HER2/DHFR-IN-3
EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values …
Purity:
98%
Ref: TM-T82492
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Oritinib
CAS:2035089-28-0
Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 …
Formula:
C31H37N7O2
Purity:
98.4%
Color and Shape:
Soild
Molecular weight:
539.67
Ref: TM-T60076
| 1mg | 131.00 € | ||
| 5mg | 314.00 € | ||
| 10mg | 458.00 € | ||
| 25mg | 759.00 € | ||
| 50mg | 1,012.00 € | ||
| 100mg | 1,383.00 € | ||
| 1mL*10mM (DMSO) | 365.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Cisapride hydrate
CAS:260779-88-2
Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of …
Formula:
C23H31ClFN3O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
483.97
Ref: TM-T22296
| 500mg | 552.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
