BTK
BTK (Bruton's tyrosine kinase) inhibitors are compounds that specifically target and inhibit BTK, a crucial enzyme involved in B-cell receptor signaling and the regulation of angiogenesis. BTK plays a significant role in the proliferation and survival of cancer cells, particularly in hematological malignancies. By inhibiting BTK, these compounds can disrupt angiogenesis and tumor growth, making them valuable in cancer therapy. At CymitQuimica, we offer a range of high-quality BTK inhibitors to support your research in oncology, immunology, and angiogenesis.
Found 167 products of "BTK"
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Fenebrutinib
CAS:Fenebrutinib (GDC-0853) is a selective and noncovalent Btk inhibitor (Ki: 0.91 nM).
Formula:C37H44N8O4Purity:98.26% - 98.94%Color and Shape:SolidMolecular weight:664.8Remibrutinib
CAS:Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.Formula:C27H27F2N5O3Purity:99.5% - 99.81%Color and Shape:SolidMolecular weight:507.53Ref: TM-T16730
1mg92.00€5mg210.00€1mL*10mM (DMSO)235.00€10mg340.00€25mg572.00€50mg713.00€100mg1,099.00€200mg1,485.00€Acalabrutinib
CAS:Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.Formula:C26H23N7O2Purity:98.94% - 99.64%Color and Shape:SolidMolecular weight:465.51Ref: TM-T3626
5mg44.00€1mL*10mM (DMSO)48.00€10mg57.00€25mg78.00€50mg90.00€100mg144.00€200mg215.00€500mg355.00€BIIB068
CAS:BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Formula:C23H29N7O2Purity:97.98%Color and Shape:SolidMolecular weight:435.52Ref: TM-T9192
1mg46.00€5mg90.00€1mL*10mM (DMSO)100.00€10mg152.00€25mg264.00€50mg398.00€100mg532.00€200mg705.00€Ibrutinib deacryloylpiperidine
CAS:Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.Formula:C17H13N5OPurity:99.47%Color and Shape:SolidMolecular weight:303.32Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formula:C26H26FN7O2Purity:99.81% - >99.99%Color and Shape:SolidMolecular weight:487.53PCI 29732
CAS:PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.Formula:C22H21N5OPurity:99.81%Color and Shape:SolidMolecular weight:371.43CHMFL-BMX-078
CAS:CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.Formula:C33H35N7O6Purity:>99.99%Color and Shape:SolidMolecular weight:625.67CNX-774
CAS:CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).Formula:C26H22FN7O3Purity:97.35% - 99.11%Color and Shape:SolidMolecular weight:499.5Ref: TM-T2302
1mg38.00€2mg50.00€5mg84.00€1mL*10mM (DMSO)88.00€10mg119.00€25mg222.00€50mg369.00€100mg537.00€500mg1,161.00€N-piperidine Ibrutinib
CAS:N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.Formula:C22H22N6OPurity:96.65%Color and Shape:SolidMolecular weight:386.45(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formula:C11H8Br2N2O2Purity:99.88%Color and Shape:SolidMolecular weight:360ONO-4059 analog
CAS:ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formula:C25H24N6O3Purity:99.25%Color and Shape:SolidMolecular weight:456.5Ref: TM-T6921
1mg43.00€2mg56.00€1mL*10mM (DMSO)90.00€5mg93.00€10mg137.00€25mg264.00€50mg439.00€100mg627.00€(Rac)-IBT6A
CAS:(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formula:C22H22N6OPurity:99.24%Color and Shape:SolidMolecular weight:386.45Ref: TM-T10626
1mg44.00€2mg57.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg120.00€25mg215.00€50mg313.00€100mg439.00€200mg628.00€RN486
CAS:RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).Formula:C35H35FN6O3Purity:99.38%Color and Shape:SolidMolecular weight:606.69Spebrutinib
CAS:Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplasticFormula:C22H22FN5O3Purity:97.02% - >99.99%Color and Shape:SolidMolecular weight:423.44TL-895
CAS:TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).Formula:C25H26FN5O2Purity:99.96%Color and Shape:SolidMolecular weight:447.5Ref: TM-T9705
2mg39.00€5mg60.00€1mL*10mM (DMSO)60.00€10mg87.00€25mg172.00€50mg266.00€100mg391.00€200mg555.00€CGI-1746
CAS:CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.Formula:C34H37N5O4Purity:97.69% - 97.88%Color and Shape:SolidMolecular weight:579.69Branebrutinib
CAS:Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family.Formula:C20H23FN4O2Purity:95.86% - 99.31%Color and Shape:SolidMolecular weight:370.42Olmutinib
CAS:Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.Formula:C26H26N6O2SPurity:99.14% - 99.63%Color and Shape:SolidMolecular weight:486.59Ref: TM-T6918
2mg37.00€5mg54.00€1mL*10mM (DMSO)56.00€10mg84.00€25mg130.00€50mg170.00€100mg268.00€200mg437.00€zanubrutinib
CAS:Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK).Formula:C27H29N5O3Purity:98.42% - 99.76%Color and Shape:SolidMolecular weight:471.55Ref: TM-T7584
1mg59.00€5mg137.00€1mL*10mM (DMSO)142.00€10mg236.00€25mg492.00€50mg737.00€100mg1,018.00€
