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BTK

BTK

BTK (Bruton's tyrosine kinase) inhibitors are compounds that specifically target and inhibit BTK, a crucial enzyme involved in B-cell receptor signaling and the regulation of angiogenesis. BTK plays a significant role in the proliferation and survival of cancer cells, particularly in hematological malignancies. By inhibiting BTK, these compounds can disrupt angiogenesis and tumor growth, making them valuable in cancer therapy. At CymitQuimica, we offer a range of high-quality BTK inhibitors to support your research in oncology, immunology, and angiogenesis.

Found 145 products of "BTK"

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  • GDC-0834 S-enantiomer
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    GDC-0834 S-enantiomer

    CAS:
    <p>GDC-0834, the S-enantiomer, is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK).</p>
    Formula:C33H36N6O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:596.74

    Ref: TM-T11378

  • CHMFL-EGFR-202
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    CHMFL-EGFR-202

    CAS:
    <p>CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases).</p>
    Formula:C25H24ClN7O2
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:489.96

    Ref: TM-T10802

  • Tilfrinib
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    Tilfrinib

    CAS:
    <p>Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.</p>
    Formula:C17H13N3O
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:275.3

    Ref: TM-T17098

  • NX-2127
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    NX-2127

    CAS:
    <p>NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative</p>
    Formula:C39H45N9O5
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:719.83

    Ref: TM-T73463

  • (±)-Zanubrutinib
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    (±)-Zanubrutinib

    CAS:
    <p>(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability,</p>
    Formula:C27H29N5O3
    Purity:99.09%
    Color and Shape:Solid
    Molecular weight:471.55

    Ref: TM-TQ0039

  • (R)-Zanubrutinib
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    (R)-Zanubrutinib

    CAS:
    <p>(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).</p>
    Formula:C27H29N5O3
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:471.55

    Ref: TM-T13447

  • (Rac)-PF-06250112
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    (Rac)-PF-06250112

    CAS:
    <p>(Rac)-PF-0625011 is a racemic mix, orally active, selective BTK inhibitor, also targeting BMX and TEC kinases.</p>
    Formula:C22H20F2N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.43

    Ref: TM-T12673

  • BTK-IN-19
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    BTK-IN-19

    CAS:
    <p>BTK-IN-19 is a reversible BTK inhibitor with an IC 50 of &lt;0.001 μM .</p>
    Formula:C21H22Cl2N6O
    Color and Shape:Solid
    Molecular weight:445.35

    Ref: TM-T73319

  • BTK inhibitor 20
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    BTK inhibitor 20

    CAS:
    <p>BTK inhibitor 20 is a potent BTK inhibitor with an IC 50 of 8 nM .</p>
    Formula:C37H42N8O4
    Color and Shape:Solid
    Molecular weight:662.78

    Ref: TM-T72664

  • BTK-IN-18
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    BTK-IN-18

    CAS:
    <p>BTK-IN-18 is a potent, reversible inhibitor of Bruton's tyrosine kinase (BTK) with an inhibitory concentration (IC50) of 0.002 µM.</p>
    Formula:C20H22Cl2N6O
    Color and Shape:Solid
    Molecular weight:433.33

    Ref: TM-T73318

  • BTK-IN-17
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    BTK-IN-17

    <p>BTK-IN-17: selective, oral BTK inhibitor, IC50=13.7 nM, reduces p-BTK Y223/p-PLCγ2 Y1217, anti-inflammatory.</p>
    Formula:C26H23N7O2
    Color and Shape:Solid
    Molecular weight:465.51

    Ref: TM-T73303

  • BTK-IN-11
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    BTK-IN-11

    CAS:
    <p>BTK-IN-11: potent BTK inhibitor; may research autoimmune, inflammatory diseases, cancer. (Patent WO2022063101A1, Z2)</p>
    Formula:C26H22ClN5O3
    Color and Shape:Solid
    Molecular weight:487.94

    Ref: TM-T63254

  • PF-303
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    PF-303

    CAS:
    <p>PF-303, a reversible covalent BTK inhibitor, shows potential for cancer and autoimmune therapy.</p>
    Formula:C22H21ClN6O2
    Color and Shape:Solid
    Molecular weight:436.89

    Ref: TM-T70393

  • BTK inhibitor 13
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    BTK inhibitor 13

    CAS:
    <p>BTK inhibitor 13 (compound 8) is an effective and selective BTK inhibitor(IC50: 1.2 nM).</p>
    Formula:C29H26FN5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:511.55

    Ref: TM-T10628

  • Pirtobrutinib
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    Pirtobrutinib

    CAS:
    <p>Pirtobrutinib: a selective, non-covalent BTK inhibitor effective against BTK C481 mutations, causing tumor regression in lymphoma models.</p>
    Formula:C22H21F4N5O3
    Purity:99.76% - 99.94%
    Color and Shape:Solid
    Molecular weight:479.43

    Ref: TM-T36287

  • Cinsebrutinib
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    Cinsebrutinib

    CAS:
    <p>Cinsebrutinib, a Bruton's tyrosine kinase inhibitor, holds potential for research in cancer treatment.</p>
    Formula:C22H26FN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:383.46

    Ref: TM-T79841

  • Edralbrutinib
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    Edralbrutinib

    CAS:
    <p>Edralbrutinib (TG-1701) is a potent BTK inhibitor with anticancer activity and is used in the treatment of tumors, immune system disorders, and blood and</p>
    Formula:C26H21F2N5O3
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:489.47

    Ref: TM-T63272

  • BMX-IN-1
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    BMX-IN-1

    CAS:
    <p>BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine</p>
    Formula:C29H24N4O4S
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:524.59

    Ref: TM-T14692

  • PF-06250112
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    PF-06250112

    CAS:
    <p>PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM.</p>
    Formula:C22H20F2N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.43

    Ref: TM-T12673L

  • TAK-020
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    TAK-020

    CAS:
    <p>TAK-020 is a potent covalent inhibitor of Btk with potential antitumor activity for the study of rheumatoid arthritis and immune-related diseases.</p>
    Formula:C18H17N5O3
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:351.36

    Ref: TM-T9529