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Syk

Syk

Syk (spleen tyrosine kinase) inhibitors are compounds that target Syk, a kinase involved in immune cell signaling and the regulation of angiogenesis. Syk plays a role in the inflammatory responses that can contribute to tumor angiogenesis. Inhibiting Syk can reduce inflammation-induced blood vessel formation in tumors, making these inhibitors valuable in cancer therapy and inflammation research. At CymitQuimica, we offer a diverse range of high-quality Syk inhibitors to support your research in immunology, oncology, and angiogenesis.

Found 37 products of "Syk"

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  • Cerdulatinib

    CAS:
    <p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>
    Formula:C20H27N7O3S
    Purity:98.74% - 99.49%
    Color and Shape:Solid
    Molecular weight:445.54
  • MNS

    CAS:
    <p>MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.</p>
    Formula:C9H7NO4
    Purity:98.53%
    Color and Shape:Yellow Powder
    Molecular weight:193.16
  • R112

    CAS:
    <p>R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.</p>
    Formula:C16H13FN4O2
    Purity:99.27% - 99.84%
    Color and Shape:Solid
    Molecular weight:312.3
  • Fostamatinib Disodium

    CAS:
    <p>Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.</p>
    Formula:C23H24FN6O9P·2Na
    Purity:96.13% - 99.09%
    Color and Shape:Solid
    Molecular weight:624.42
  • Entospletinib

    CAS:
    <p>Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!</p>
    Formula:C23H21N7O
    Purity:98.54% - 99.51%
    Color and Shape:Solid
    Molecular weight:411.46
  • R406

    CAS:
    <p>R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.</p>
    Formula:C22H23FN6O5·C6H6O3S
    Purity:97.67% - 98.82%
    Color and Shape:Solid
    Molecular weight:628.63
  • R406 free base

    CAS:
    <p>R406 free base (R406 (free base)) is a potent Syk inhibitor.</p>
    Formula:C22H23FN6O5
    Purity:97.64% - 99.11%
    Color and Shape:Solid
    Molecular weight:470.45
  • Cerdulatinib hydrochloride

    CAS:
    <p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 &lt; 200 nM.</p>
    Formula:C20H28ClN7O3S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:482
  • Syk Inhibitor II

    CAS:
    <p>Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).</p>
    Formula:C14H15F3N6O
    Purity:97.63%
    Color and Shape:Solid
    Molecular weight:340.3
  • ER-27319

    CAS:
    <p>ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine</p>
    Formula:C20H22N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:370.4
  • Sovleplenib

    CAS:
    <p>Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors &amp; ITP studies.</p>
    Formula:C24H30N6O3S
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:482.6
  • RO9021

    CAS:
    <p>RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).</p>
    Formula:C18H25N7O
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:355.44
  • Syk-IN-3

    CAS:
    <p>Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.</p>
    Formula:C24H28N4O3S
    Purity:97.29% - >99.99%
    Color and Shape:Solid
    Molecular weight:452.57
  • OXSI-2

    CAS:
    <p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>
    Formula:C18H15N3O3S
    Purity:98%
    Color and Shape:Dark Orange Solid
    Molecular weight:353.39
  • Lanraplenib monosuccinate

    CAS:
    <p>Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.</p>
    Formula:C27H31N9O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:561.59
  • MK-8457

    CAS:
    <p>MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].</p>
    Formula:C24H25F3N4O3S
    Color and Shape:Solid
    Molecular weight:506.54
  • Syk-IN-8

    CAS:
    <p>Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.</p>
    Formula:C23H26N10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:442.52

    Ref: TM-T79443

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