Syk
Syk (spleen tyrosine kinase) inhibitors are compounds that target Syk, a kinase involved in immune cell signaling and the regulation of angiogenesis. Syk plays a role in the inflammatory responses that can contribute to tumor angiogenesis. Inhibiting Syk can reduce inflammation-induced blood vessel formation in tumors, making these inhibitors valuable in cancer therapy and inflammation research. At CymitQuimica, we offer a diverse range of high-quality Syk inhibitors to support your research in immunology, oncology, and angiogenesis.
Found 37 products of "Syk"
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Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.54Ref: TM-T2487
1mg42.00€2mg52.00€5mg74.00€1mL*10mM (DMSO)81.00€10mg101.00€25mg175.00€50mg268.00€100mg409.00€200mg573.00€500mg888.00€MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purity:98.53%Color and Shape:Yellow PowderMolecular weight:193.16R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formula:C16H13FN4O2Purity:99.27% - 99.84%Color and Shape:SolidMolecular weight:312.3Ref: TM-T3185
1mg37.00€2mg49.00€5mg79.00€1mL*10mM (DMSO)87.00€10mg117.00€25mg207.00€50mg311.00€100mg462.00€500mg973.00€Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurity:96.13% - 99.09%Color and Shape:SolidMolecular weight:624.42Ref: TM-T2605
1mg44.00€2mg52.00€5mg84.00€1mL*10mM (DMSO)110.00€10mg117.00€25mg210.00€50mg354.00€100mg530.00€500mg1,153.00€Entospletinib
CAS:Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Formula:C23H21N7OPurity:98.54% - 99.74%Color and Shape:SolidMolecular weight:411.46Ref: TM-T6101
1mg35.00€2mg50.00€5mg77.00€1mL*10mM (DMSO)84.00€10mg92.00€25mg166.00€50mg245.00€100mg394.00€200mg585.00€R406
CAS:R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Formula:C22H23FN6O5·C6H6O3SPurity:97.67% - 98.82%Color and Shape:SolidMolecular weight:628.63Ref: TM-T6174
1mg46.00€2mg57.00€5mg89.00€1mL*10mM (DMSO)120.00€10mg142.00€25mg299.00€50mg445.00€100mg647.00€R406 free base
CAS:R406 free base (R406 (free base)) is a potent Syk inhibitor.Formula:C22H23FN6O5Purity:97.64% - 99.11%Color and Shape:SolidMolecular weight:470.45Ref: TM-T2467
1mg44.00€5mg66.00€1mL*10mM (DMSO)69.00€10mg92.00€25mg177.00€50mg319.00€100mg507.00€500mg1,063.00€Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurity:99.85%Color and Shape:SolidMolecular weight:482Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Formula:C14H15F3N6OPurity:97.63%Color and Shape:SolidMolecular weight:340.3ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFormula:C20H22N2O5Purity:98%Color and Shape:SolidMolecular weight:370.4Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Formula:C24H30N6O3SPurity:99.71%Color and Shape:SolidMolecular weight:482.6Ref: TM-T32088
1mg120.00€5mg289.00€1mL*10mM (DMSO)308.00€10mg434.00€25mg737.00€50mg1,153.00€100mg1,791.00€200mg2,412.00€RO9021
CAS:RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Formula:C18H25N7OPurity:99.90%Color and Shape:SolidMolecular weight:355.44Syk-IN-3
CAS:Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.Formula:C24H28N4O3SPurity:97.29% - >99.99%Color and Shape:SolidMolecular weight:452.57OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Formula:C18H15N3O3SPurity:98%Color and Shape:Dark Orange SolidMolecular weight:353.39Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Formula:C27H31N9O5Purity:98%Color and Shape:SolidMolecular weight:561.59MK-8457
CAS:MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].Formula:C24H25F3N4O3SColor and Shape:SolidMolecular weight:506.54Syk-IN-8
CAS:Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.
Formula:C23H26N10Purity:98%Color and Shape:SolidMolecular weight:442.52
