CymitQuimica logo
ASK

ASK

ASK (Apoptosis Signal-regulating Kinase) inhibitors target the ASK family of kinases, which are critical regulators of apoptosis and stress response pathways. ASK kinases are involved in the activation of apoptosis in response to various stress signals, including oxidative stress and DNA damage. By inhibiting ASK, these compounds can modulate apoptotic signaling, providing valuable tools for research into cell death, cancer, and neurodegenerative diseases. At CymitQuimica, we offer a range of high-quality ASK inhibitors to support your research in apoptosis, cell signaling, and disease mechanisms.

Found 6 products of "ASK"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
  • Anti-DBF4 Antibody (2Q22)


    <p>Anti-DBF4 Antibody (2Q22) is an antibody targeting DBF4. Anti-DBF4 Antibody (2Q22) can be used in ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200.</p>
    Color and Shape:Odour Liquid
  • ASK1-IN-1

    CAS:
    <p>ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.</p>
    Formula:C19H19N9O2
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:405.41
  • MSC 2032964A

    CAS:
    <p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>
    Formula:C16H13F3N6O
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:362.31
  • CDK8/19-IN-1

    CAS:
    <p>CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).</p>
    Formula:C19H18N4O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.5
  • ASK1-IN-8

    CAS:
    <p>ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.</p>
    Formula:C26H32N8O2
    Color and Shape:Solid
    Molecular weight:488.585
  • ASK1-IN-7

    CAS:
    <p>ASK1-IN-7 (Compound 4c) is an ASK1 inhibitor and a derivative of the ASK1 inhibitor scaffold 5-(5-Phenyl-furan-2-ylmethylene)-2-thioxo-thiazolidin-4-one. This compound is potentially applicable in research involving ASK1 signaling pathways, including studies on cellular stress response, inflammatory response, neurodegenerative diseases, and cardiovascular diseases.</p>
    Formula:C13H8N2O2S2
    Color and Shape:Solid
    Molecular weight:288.345