PD-1/PD-L1
PD-1/PD-L1 inhibitors are immune checkpoint inhibitors that block the interaction between the programmed cell death protein 1 (PD-1) on T cells and its ligand PD-L1 on cancer cells. This interaction normally suppresses the immune response and allows cancer cells to evade immune detection. By inhibiting PD-1/PD-L1, these inhibitors enhance the immune system's ability to recognize and destroy cancer cells, inducing apoptosis and tumor regression. PD-1/PD-L1 inhibitors are critical in immunotherapy research and cancer treatment. At CymitQuimica, we offer a range of high-quality PD-1/PD-L1 inhibitors to support your research in immuno-oncology, apoptosis, and cancer therapy.
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BMS-1001 hydrochloride
CAS:2113650-04-5
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in …
Formula:
C35H35ClN2O7
Purity:
97.36%
Color and Shape:
Solid
Molecular weight:
631.11
Ref: TM-T10565
| 1mg | 56.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 194.00 € | ||
| 25mg | 394.00 € | ||
| 50mg | 632.00 € | ||
| 100mg | 1,003.00 € | ||
| 200mg | 1,359.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
IMMH 010 maleate
CAS:2541982-47-0
IMMH 010 maleate (YPD-30 maleate) is a programmed cell death ligand 1 inhibitor used in …
Formula:
C36H36BrClN2O9
Color and Shape:
Soild
Molecular weight:
756.04
Ref: TM-T83970
| 1mg | 184.00 € | ||
| 5mg | 455.00 € | ||
| 10mg | 652.00 € | ||
| 25mg | 1,017.00 € | ||
| 50mg | 1,403.00 € | ||
| 100mg | 1,855.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Tislelizumab
CAS:1858168-59-8
Tislelizumab, a PD-1 receptor monoclonal antibody, reduces Fcγ interaction and T cell clearance in advanced …
Purity:
95%
Color and Shape:
Liquid
Ref: TM-T76703
| 1mg | 95.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 424.00 € | ||
| 25mg | 684.00 € | ||
| 50mg | 920.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Anti-Mouse PD-L1 Antibody (10F.9G2)
Anti-Mouse PD-L1 Antibody (10F.9G2) is an IgG-class antibody against mouse PD-L1.
Purity:
98.92%
Ref: TM-T78270
| 1mg | 74.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PD-1/PD-L1-IN-31
PD-1/PD-L1-IN-31 is a potent inhibitor of PD-1/PD-L1 (IC50=2.2 nM) that enhances IFN-γ secretion and activates …
Formula:
C24H24ClFN2O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
442.91
Ref: TM-T78755
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
(D)-PPA 1 TFA
(D)-PPA 1 TFA is a hydrolysis-resistant D-peptide antagonist and a potent PD-1/PD-L1 inhibitor, exhibiting an …
Formula:
C72H99F3N20O23
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1669.67
Ref: TM-T78222
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
PD-1/PD-L1-IN-32
PD-1/PD-L1-IN-32 (compound A56) is a potent inhibitor of PD-1/PD-L1, displaying pronounced anticancer activity with an …
Purity:
98%
Ref: TM-T79576
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
PD-1/PD-L1-IN-9
CAS:2628506-54-5
PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of …
Formula:
C22H24N2O2
Purity:
99.37%
Color and Shape:
Liquid
Molecular weight:
348.44
Ref: TM-T9651
| 1mg | 60.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 308.00 € | ||
| 50mg | 420.00 € | ||
| 100mg | 554.00 € | ||
| 500mg | 1,098.00 € | ||
| 1mL*10mM (DMSO) | 148.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ARB-272572 hydrochloride
CAS:2377524-19-9
ARB-272572 hydrochloride is a PD-L1 inhibitor that inhibits PD-1/PD-L1 cell signaling by inducing PD-L1 protein …
Formula:
C32H36N6O4·xClH
Purity:
99%
Color and Shape:
Soild
Molecular weight:
568.68(Free base）
Ref: TM-T83976
| 1mg | 185.00 € | ||
| 25mg | 1,016.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Latikafusp
CAS:2552814-07-8
Latikafusp (AMG 256) is a fusion protein that is a PD-1 blocker and IL-21R agonist …
Color and Shape:
Liquid
Ref: TM-T77052
| 1mg | 498.00 € | ||
| 5mg | 1,278.00 € | ||
| 10mg | 1,555.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
LP23
LP23, a non-arylmethylamine PD-1/PD-L1 inhibitor (IC 50: 16.7 nM), exhibits anti-tumor activity through the restoration …
Formula:
C27H27N3O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
505.59
Ref: TM-T79705
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride
CAS:2691796-83-3
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand …
Formula:
C41H45Cl3N4O5
Purity:
98%
Color and Shape:
Soild
Molecular weight:
780.18
Ref: TM-T40111L
| 1mg | 178.00 € | ||
| 5mg | 450.00 € | ||
| 10mg | 715.00 € | ||
| 25mg | 1,473.00 € | ||
| 50mg | 2,326.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARB-272572
CAS:2368182-63-0
ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.
Formula:
C32H36N6O4
Color and Shape:
Liquid
Molecular weight:
568.67
Ref: TM-T39914
| 1mg | 149.00 € | ||
| 5mg | 297.00 € | ||
| 10mg | 450.00 € | ||
| 25mg | 750.00 € | ||
| 50mg | 1,105.00 € | ||
| 100mg | 1,494.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD-1/PD-L1-IN-10
CAS:2487550-41-2
PD-1/PD-L1-IN-10 is an orally available PD-1/PD-L1 inhibitor (IC50 value of 2.7 nM) that shows anti-tumor …
Formula:
C33H31N3O7
Purity:
97.81%
Color and Shape:
Solid
Molecular weight:
581.62
Ref: TM-T9616
| 1mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 310.00 € | ||
| 50mg | 554.00 € | ||
| 100mg | 794.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS-1001
CAS:2113650-03-4
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved …
Formula:
C35H34N2O7
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
594.7
Ref: TM-T8470
| 1mg | 60.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 430.00 € | ||
| 100mg | 598.00 € | ||
| 200mg | 805.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS-8
CAS:1675201-90-7
BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly …
Formula:
C27H28BrNO3
Purity:
99.06%
Color and Shape:
Solid
Molecular weight:
494.42
Ref: TM-T26859
| 1mg | 39.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 265.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 624.00 € | ||
| 500mg | 1,332.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS-1166
CAS:1818314-88-3
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.
Formula:
C36H33ClN2O7
Purity:
99.22%
Color and Shape:
Solid
Molecular weight:
641.11
Ref: TM-T5697
| 1mg | 96.00 € | ||
| 2mg | 121.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 292.00 € | ||
| 25mg | 540.00 € | ||
| 50mg | 770.00 € | ||
| 100mg | 1,067.00 € | ||
| 1mL*10mM (DMSO) | 258.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PDL-1 cpd 10
CAS:2767424-13-3
PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.
Formula:
C21H23N5O2
Purity:
97.08%
Color and Shape:
Solid
Molecular weight:
377.44
Ref: TM-T9359
| 1mg | 53.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 378.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 758.00 € | ||
| 200mg | 998.00 € | ||
| 1mL*10mM (DMSO) | 129.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS202 hydrochloride (1675203-84-5(free base))
CAS:2089334-95-0
BMS202 hydrochloride (1675203-84-5) is a potent PD-1/PD-L1 inhibitor (IC50: 18 nM) that promotes PD-L1 dimerization, …
Formula:
C25H30ClN3O3
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
455.97
Ref: TM-T4696
| 1mg | 52.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 545.00 € | ||
| 100mg | 780.00 € | ||
| 1mL*10mM (DMSO) | 100.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PD-1-IN-22
CAS:2349372-98-9
PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of …
Formula:
C25H25N5O4
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
459.5
Ref: TM-T12379
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 775.00 € | ||
| 100mg | 1,040.00 € | ||
| 500mg | 2,098.00 € | ||
| 1mL*10mM (DMSO) | 298.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
