TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Found 65 products of "TNF"
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Conatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.44 kDaCertolizumab pegol
CAS:Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.Purity:96.7% (SDS-PAGE); 96.5% (SEC-HPLC) - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:47.74 kDaUCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Formula:C26H25N5OPurity:98.39% - 99.24%Color and Shape:SolidMolecular weight:423.51Ref: TM-T13951
1mg92.00€2mg133.00€5mg219.00€10mg353.00€25mg602.00€50mg802.00€100mg1,108.00€200mg1,485.00€1mL*10mM (DMSO)245.00€(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formula:C27H39N5O7Purity:97.61% - 99.72%Color and Shape:SolidMolecular weight:545.63Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purity:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:142.77 kDaOnfekafusp alfa
CAS:Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.Color and Shape:LiquidTilogotamab
CAS:Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).Purity:95%Color and Shape:LiquidMolecular weight:144.88 kDaTNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Formula:C17H14O4Purity:99.21%Color and Shape:SoildMolecular weight:282.29Ragifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.
Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:146.46 kDaRO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Color and Shape:Odour LiquidPamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Purity:95%Color and Shape:LiquidMolecular weight:145.20 kDaTengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Color and Shape:LiquidVarlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Purity:SDS-PAGE:95% SEC-HPLC:98.65%Color and Shape:LiquidMolecular weight:146 kDaLenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Color and Shape:LiquidEfaprinermin alfa
CAS:Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].Color and Shape:LiquidRanevetmab
CAS:Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.Color and Shape:LiquidTanfanercept
CAS:Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.Color and Shape:LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Purity:95%Color and Shape:Odour LiquidMolecular weight:150 kDaKGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Formula:C84H129N21O22SColor and Shape:SolidMolecular weight:1817.12MK-4166
MK-4166 is a humanized IgG1 agonistic monoclonal antibody targeting GITR. It is capable of enhancing the proliferation of both naive T lymphocytes and tumor-infiltrating T lymphocytes.HS-243
CAS:HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
Formula:C17H16N4O3Purity:98.62%Color and Shape:SolidMolecular weight:324.33Dapirolizumab
Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.Purity:>95%Color and Shape:LiquidMolecular weight:150 kDaOnercept
CAS:Onercept, a recombinant soluble form of the human tumor necrosis factor-alpha (TNF-α) p55 receptor, is utilized in the study of Crohn's disease [1].Color and Shape:LiquidTelitacicept
CAS:Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligandColor and Shape:LiquidPegsunercept
CAS:Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].Color and Shape:LiquidTNF-α Antagonist
CAS:TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFormula:C58H71N11O15S2Color and Shape:SolidMolecular weight:1226.39TNF-α (46-65), human
CAS:Human TNF alpha (46-65) peptide.Formula:C110H172N24O30Purity:98%Color and Shape:SolidMolecular weight:2310.69DSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.Formula:C66H108F3N15O28Color and Shape:SolidMolecular weight:1616.64EJMC-1
CAS:EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.Formula:C17H11ClN2O4SPurity:98.38%Color and Shape:SolidMolecular weight:374.8Acetyl tetrapeptide-2
CAS:Acetyl tetrapeptide-2 is a skin conditioner, by soothing and nourishing the skin through similar mechanisms as other peptides.Formula:C26H39N5O9Purity:98%Color and Shape:SolidMolecular weight:565.62TNF α Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Purity:> 90% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 90% as determined by Bis-Tris PAGE > 95% as determined by HPLCColor and Shape:Lyophilized PowderMolecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Ferret, Recombinant (His)
TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:18.88 kDa (predicted) same as Tris-Bis PAGE result.TNF α Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.Color and Shape:Lyophilized PowderMolecular weight:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00121
5µg91.00€10µg150.00€20µg239.00€50µg471.00€100µg779.00€200µg1,410.00€500µg3,018.00€TNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.Purity:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Color and Shape:Lyophilized PowderMolecular weight:16 KDa (reducing condition)Ref: TM-TMPJ-00124
1mg1,017.00€5µg42.00€10µg59.00€20µg87.00€50µg130.00€100µg210.00€200µg354.00€500µg709.00€TNF α Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:18 KDa (reducing condition)Ref: TM-TMPJ-00125
1mg2,758.00€5µg113.00€10µg178.00€20µg284.00€50µg523.00€100µg779.00€200µg1,142.00€500µg1,923.00€TNF α Protein, Rabbit, Recombinant
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.Purity:98% - > 99.9%Color and Shape:Lyophilized PowderMolecular weight:18 KDa (reducing condition)LASSBio-1135
CAS:LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.Formula:C18H14N4Purity:99.09%Color and Shape:SolidMolecular weight:286.33R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formula:C16H8ClF3N4SPurity:98.64% - 99.8%Color and Shape:SolidMolecular weight:380.77Ref: TM-T4637
1mg34.00€2mg43.00€5mg63.00€10mg90.00€25mg195.00€50mg268.00€100mg439.00€200mg623.00€1mL*10mM (DMSO)71.00€(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formula:C16H16N6OPurity:98.44%Color and Shape:SolidMolecular weight:308.34Ref: TM-T8692
1mg46.00€2mg62.00€5mg92.00€10mg152.00€25mg295.00€50mg442.00€100mg620.00€200mg875.00€1mL*10mM (DMSO)105.00€Hispidol
CAS:Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colonFormula:C15H10O4Purity:97.86% - 98.45%Color and Shape:SolidMolecular weight:254.24Ref: TM-T4319
1mg42.00€2mg56.00€5mg93.00€10mg137.00€25mg200.00€50mg260.00€100mg409.00€200mg560.00€500mg954.00€1mL*10mM (DMSO)92.00€STING-IN-2
CAS:STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.Formula:C15H16N2O4Purity:98.61%Color and Shape:SolidMolecular weight:288.3Roquinimex
CAS:Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis andFormula:C18H16N2O3Purity:97.69%Color and Shape:SolidMolecular weight:308.33N-Formyl-Met-Leu-Phe
CAS:N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).Formula:C21H31N3O5SPurity:98.69% - 98.69%Color and Shape:SolidMolecular weight:437.55Resatorvid
CAS:Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.
Formula:C15H17ClFNO4SPurity:99.31% - >99.99%Color and Shape:SolidMolecular weight:361.82UTL-5g
CAS:UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.
Formula:C11H8Cl2N2O2Purity:99.83%Color and Shape:SolidMolecular weight:271.1Tulisokibart
CAS:Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.Purity:98.38% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:143.96 kDaLicaminlimab
Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.Color and Shape:Odour LiquidIratumumab
CAS:Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.Color and Shape:LiquidTavolixizumab
CAS:Tavolixizumab (also known as MEDI 0562 and Tavolimab) is a human monoclonal antibody targeting TNFRSF4 (TNF receptor superfamily member 4), utilized in cancerColor and Shape:Liquid
