TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Found 92 products of "TNF"
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Dacetuzumab
CAS:<p>Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.</p>Purity:95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)Color and Shape:LiquidTeneliximab
CAS:<p>Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.</p>Purity:95.00% - 99.19% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.06 kDaEnavatuzumab
CAS:<p>Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.</p>Purity:>95%Color and Shape:LiquidUCB-9260
CAS:<p>UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.</p>Formula:C26H25N5OPurity:98.39% - 99.24%Color and Shape:SolidMolecular weight:423.51Lucatumumab
CAS:<p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>Purity:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:LiquidCertolizumab pegol
CAS:<p>Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.</p>Purity:95% - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Color and Shape:LiquidRuplizumab
CAS:<p>PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.</p>Purity:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidUtomilumab
CAS:<p>Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.</p>Formula:C17H24N8O3Purity:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:142.77 kDa(S,S)-TAPI-1 FA
<p>(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.</p>Formula:C27H39N5O7Purity:97.61% - 99.72%Color and Shape:SolidMolecular weight:545.63Ozoralizumab
CAS:<p>Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.</p>Purity:SDS-PAGE:> 95%;SEC-HPLC:95.6%Color and Shape:LiquidMolecular weight:38.44 kDaConatumumab
CAS:<p>Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145 kDa (average)Iscalimab
CAS:<p>Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.</p>Purity:>95%Color and Shape:LiquidVarlilumab
CAS:<p>Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.</p>Purity:SDS-PAGE:95% SEC-HPLC:98.65%Color and Shape:LiquidMolecular weight:146 kDaZigakibart
CAS:<p>Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)</p>Purity:95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Color and Shape:LiquidRagifilimab
CAS:<p>Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.</p>Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:146.46 kDaCot inhibitor-1 hydrochloride
<p>Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.</p>Formula:C27H28Cl3FN8Purity:98.26%Color and Shape:SoildMolecular weight:589.92TNF-α-IN-9
CAS:<p>TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.</p>Formula:C17H14O4Purity:98.28%Color and Shape:SoildMolecular weight:282.29Anti-Mouse TNF α Antibody (TN3-19.12)
<p>Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.</p>Purity:95% - ＞10mg/mlColor and Shape:Odour LiquidRO7567132
<p>RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.</p>Color and Shape:Odour LiquidPamlectabart
<p>Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.</p>Purity:95%Color and Shape:Odour LiquidRelfovetmab
CAS:<p>Relfovetmab is an anti- NGF monoclonal antibody (mAb) [1] .</p>Color and Shape:LiquidOnfekafusp alfa
CAS:<p>Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.</p>Color and Shape:LiquidTengonermin
CAS:<p>Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.</p>Color and Shape:LiquidPegsunercept
CAS:<p>Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].</p>Color and Shape:LiquidNerelimomab
CAS:<p>Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].</p>Color and Shape:LiquidAsunercept
CAS:<p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>Color and Shape:LiquidTanfanercept
CAS:<p>Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.</p>Color and Shape:LiquidPlaculumab
CAS:<p>Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.</p>Color and Shape:LiquidRanevetmab
CAS:<p>Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.</p>Color and Shape:LiquidLenercept
CAS:<p>Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].</p>Color and Shape:LiquidAtibuclimab
CAS:<p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.28 kDaBIIB023
<p>BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.</p>Color and Shape:Odour LiquidTNF-α Antagonist
CAS:<p>TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with</p>Formula:C58H71N11O15S2Color and Shape:SolidMolecular weight:1226.39Giloralimab
CAS:<p>Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.</p>Purity:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Color and Shape:LiquidSotigalimab
CAS:<p>Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.</p>Purity:98.50% - 98.50%Color and Shape:LiquidDapirolizumab
<p>Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.</p>Purity:>95%Color and Shape:LiquidMolecular weight:145.5 kDaHS-243
CAS:<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Formula:C17H16N4O3Purity:98.62%Color and Shape:SolidMolecular weight:324.33EJMC-1
CAS:<p>EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.</p>Formula:C17H11ClN2O4SPurity:98.38%Color and Shape:SolidMolecular weight:374.8Tilogotamab
CAS:<p>Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).</p>Purity:95%Color and Shape:LiquidTNF α Protein, Rabbit, Recombinant
<p>Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.</p>Purity:98% - > 99.9%Color and Shape:Lyophilized PowderMolecular weight:18 KDa (reducing condition)TNF α Protein, Ferret, Recombinant (His)
<p>TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.</p>Color and Shape:Lyophilized PowderMolecular weight:18.88 kDa (predicted) same as Tris-Bis PAGE result.TNF α Protein, Cynomolgus, Recombinant (His)
<p>TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.</p>Color and Shape:Lyophilized PowderMolecular weight:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (His & Avi)
<p>TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Color and Shape:Lyophilized PowderMolecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (aa 57-233, His)
<p>TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.</p>Color and Shape:Lyophilized PowderMolecular weight:18 KDa (reducing condition)TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
<p>TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Color and Shape:Lyophilized PowderMolecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (aa 77-233, His)
<p>TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.</p>Purity:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Color and Shape:Lyophilized PowderMolecular weight:16 KDa (reducing condition)QNZ
CAS:<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Formula:C22H20N4OPurity:99.17% - 99.18%Color and Shape:White SolidMolecular weight:356.42R-7050
CAS:<p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>Formula:C16H8ClF3N4SPurity:98.64% - 99.8%Color and Shape:SolidMolecular weight:380.77Hispidol
CAS:<p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>Formula:C15H10O4Purity:97.86% - 98.45%Color and Shape:SolidMolecular weight:254.24Resatorvid
CAS:<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Formula:C15H17ClFNO4SPurity:99.31% - >99.99%Color and Shape:SolidMolecular weight:361.82
