TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Found 65 products of "TNF"
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Hispidol
CAS:Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colonFormula:C15H10O4Purity:97.86% - 98.45%Color and Shape:SolidMolecular weight:254.24Ref: TM-T4319
1mg42.00€2mg56.00€5mg93.00€10mg137.00€25mg200.00€50mg260.00€100mg409.00€200mg560.00€500mg954.00€1mL*10mM (DMSO)92.00€STING-IN-2
CAS:STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.Formula:C15H16N2O4Purity:98.61%Color and Shape:SolidMolecular weight:288.3Roquinimex
CAS:Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis andFormula:C18H16N2O3Purity:97.69%Color and Shape:SolidMolecular weight:308.33N-Formyl-Met-Leu-Phe
CAS:N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).Formula:C21H31N3O5SPurity:98.69% - 98.69%Color and Shape:SolidMolecular weight:437.55Resatorvid
CAS:Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.
Formula:C15H17ClFNO4SPurity:99.31% - >99.99%Color and Shape:SolidMolecular weight:361.82UTL-5g
CAS:UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.
Formula:C11H8Cl2N2O2Purity:99.83%Color and Shape:SolidMolecular weight:271.1Tulisokibart
CAS:Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.Purity:98.38% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:143.96 kDaLicaminlimab
Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.Color and Shape:Odour LiquidIratumumab
CAS:Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.Color and Shape:LiquidTavolixizumab
CAS:Tavolixizumab (also known as MEDI 0562 and Tavolimab) is a human monoclonal antibody targeting TNFRSF4 (TNF receptor superfamily member 4), utilized in cancerColor and Shape:LiquidBoserolimab
CAS:Boserolimab (MK-5890) is a chimeric, humanized IgG1κ antibody that targets the signaling regulatory protein CD27 in mice.Purity:95% - 95%Color and Shape:LiquidTecaginlimab
CAS:Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.Color and Shape:LiquidDalnicastobart
CAS:Dalnicastobart (LVGN-7409) is a humanized monoclonal antibody targeting CD40/TNFRSF5 with agonist activity, immunostimulatory and antitumor.Purity:95% - 97.4% (SDS-PAGE); 97.8% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.33 kDaAfelimomab
CAS:Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].Color and Shape:LiquidTNF-α-IN-1
CAS:TNF-α-IN-1 is a TNF-α inhibitor.Formula:C16H14ClN3O5Purity:98.82%Color and Shape:SolidMolecular weight:363.75Ref: TM-T13175
1mg56.00€5mg120.00€10mg178.00€25mg330.00€50mg505.00€100mg713.00€1mL*10mM (DMSO)203.00€SPD304 dihydrochloride
CAS:SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.
Formula:C32H34Cl2F3N3O2Purity:99.25%Color and Shape:SolidMolecular weight:620.53UCB-5307
CAS:UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Formula:C22H21N3OPurity:98.76%Color and Shape:SolidMolecular weight:343.42PK68
CAS:PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.Formula:C22H24N4O3SPurity:98.09% - 99.64%Color and Shape:SolidMolecular weight:424.52Ref: TM-T12493
1mg81.00€5mg170.00€10mg274.00€25mg518.00€50mg747.00€100mg938.00€1mL*10mM (DMSO)188.00€BMS-561392
CAS:BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.Formula:C27H32N4O4Purity:99.16%Color and Shape:SolidMolecular weight:476.57Trovafloxacin mesylate
CAS:Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Formula:C21H19F3N4O6SPurity:99.18%Color and Shape:SolidMolecular weight:512.46
