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TNF

TNF

TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.

Found 92 products of "TNF"

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  • TNF α Protein, Ferret, Recombinant (His)


    <p>TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:18.88 kDa (predicted) same as Tris-Bis PAGE result.
  • TNF α Protein, Cynomolgus, Recombinant (His)


    <p>TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.
  • TNF α Protein, Human, Recombinant (His & Avi)


    <p>TNF alpha Protein, Human, Recombinant (His &amp; Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.
  • TNF α Protein, Human, Recombinant (aa 57-233, His)


    <p>TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:18 KDa (reducing condition)
  • TNF α Protein, Human, Recombinant (His & Avi), Biotinylated


    <p>TNF alpha Protein, Human, Recombinant (His &amp; Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.
  • TNF α Protein, Human, Recombinant (aa 77-233, His)


    <p>TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.</p>
    Purity:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%
    Color and Shape:Lyophilized Powder
    Molecular weight:16 KDa (reducing condition)
  • QNZ

    CAS:
    <p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>
    Formula:C22H20N4O
    Purity:99.17% - 99.18%
    Color and Shape:White Solid
    Molecular weight:356.42
  • R-7050

    CAS:
    <p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>
    Formula:C16H8ClF3N4S
    Purity:98.64% - 99.8%
    Color and Shape:Solid
    Molecular weight:380.77
  • Hispidol

    CAS:
    <p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>
    Formula:C15H10O4
    Purity:97.86% - 98.45%
    Color and Shape:Solid
    Molecular weight:254.24
  • Resatorvid

    CAS:
    <p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>
    Formula:C15H17ClFNO4S
    Purity:99.31% - >99.99%
    Color and Shape:Solid
    Molecular weight:361.82
  • Nodinitib-1

    CAS:
    <p>Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.</p>
    Formula:C14H13N3O2S
    Purity:99.97% - >99.99%
    Color and Shape:Solid
    Molecular weight:287.34
  • C25-140

    CAS:
    <p>C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.</p>
    Formula:C26H31N7O
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:457.57
  • (Rac)-Benpyrine

    CAS:
    <p>(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.</p>
    Formula:C16H16N6O
    Purity:98.44%
    Color and Shape:Solid
    Molecular weight:308.34
  • Roquinimex

    CAS:
    <p>Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and</p>
    Formula:C18H16N2O3
    Purity:97.69%
    Color and Shape:Solid
    Molecular weight:308.33
  • LASSBio-1135

    CAS:
    <p>LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.</p>
    Formula:C18H14N4
    Purity:99.09%
    Color and Shape:Solid
    Molecular weight:286.33
  • UTL-5g

    CAS:
    <p>UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.</p>
    Formula:C11H8Cl2N2O2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:271.1
  • STING-IN-2

    CAS:
    <p>STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.</p>
    Formula:C15H16N2O4
    Purity:98.61%
    Color and Shape:Solid
    Molecular weight:288.3
  • Tulisokibart

    CAS:
    <p>Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.</p>
    Purity:98.38% (SEC-HPLC) - > 95%
    Color and Shape:Liquid
  • Licaminlimab


    <p>Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.</p>
    Color and Shape:Odour Liquid
  • Toralizumab

    CAS:
    <p>Toralizumab: humanized mAb targeting CD40L to curb T cell signaling and explore SLE treatment.</p>
    Color and Shape:Liquid
    Molecular weight:148.43 (kD)