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p53

p53

p53 inhibitors target the p53 protein, a tumor suppressor that plays a crucial role in regulating the cell cycle, DNA repair, and apoptosis. While p53 is often mutated or inactivated in cancer cells, its inhibition is sometimes necessary to protect healthy cells from apoptosis during certain treatments. On the other hand, restoring p53 function in tumors can lead to cancer cell apoptosis. Research into p53 inhibitors is complex and significant for both understanding cancer mechanisms and developing new therapies. At CymitQuimica, we provide a selection of high-quality p53 inhibitors and modulators to support your research in cancer biology, apoptosis, and therapeutic development.

Found 64 products of "p53"

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  • CT-1

    CAS:
    CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
    Formula:C29H23F3N4O
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:500.51
  • UNC0321

    CAS:
    UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.
    Formula:C27H45N7O3
    Purity:99.80%
    Color and Shape:Solid
    Molecular weight:515.69
  • BML-259

    CAS:
    BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.
    Formula:C14H16N2OS
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:260.35
  • PDK4-IN-1 hydrochloride

    CAS:
    PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).
    Formula:C22H20ClN3O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:393.87