
p53
p53 inhibitors target the p53 protein, a tumor suppressor that plays a crucial role in regulating the cell cycle, DNA repair, and apoptosis. While p53 is often mutated or inactivated in cancer cells, its inhibition is sometimes necessary to protect healthy cells from apoptosis during certain treatments. On the other hand, restoring p53 function in tumors can lead to cancer cell apoptosis. Research into p53 inhibitors is complex and significant for both understanding cancer mechanisms and developing new therapies. At CymitQuimica, we provide a selection of high-quality p53 inhibitors and modulators to support your research in cancer biology, apoptosis, and therapeutic development.
Found 64 products of "p53"
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CT-1
CAS:CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.Formula:C29H23F3N4OPurity:99.79%Color and Shape:SolidMolecular weight:500.51UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Formula:C27H45N7O3Purity:99.80%Color and Shape:SolidMolecular weight:515.69BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formula:C14H16N2OSPurity:99.84%Color and Shape:SolidMolecular weight:260.35PDK4-IN-1 hydrochloride
CAS:PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).Formula:C22H20ClN3O2Purity:99.67%Color and Shape:SolidMolecular weight:393.87
