IAP
IAP (Inhibitor of Apoptosis Protein) inhibitors are compounds that block the activity of IAPs, a family of proteins that prevent apoptosis by inhibiting caspases and other components of the apoptotic machinery. IAP inhibitors promote apoptosis in cancer cells by neutralizing these survival signals, making them important tools in cancer research and therapy. At CymitQuimica, we offer a comprehensive range of high-quality IAP inhibitors to support your research in oncology, apoptosis, and therapeutic development.
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Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic …
Purity:
92.7%
Color and Shape:
Solid
Molecular weight:
54.1 kDa (predicted); 66 kDa (reducing conditions)
Ref: TM-TMPY-00570
| 50µg | 387.00 € | ||
| 100µg | 669.00 € | ||
| 200µg | 1,176.00 € | ||
| 500µg | 2,411.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with …
Color and Shape:
Liquid
Molecular weight:
30-40 KDa (reducing condition)
Ref: TM-TMPJ-00209
| 20µg | 358.00 € | ||
| 100µg | 951.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CD47 Protein, Human, Recombinant (hFc)
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
Color and Shape:
Liquid
Molecular weight:
40.7 kDa (predicted); 48-60 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-03883
| 1mg | 2,532.00 € | ||
| 100µg | 412.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.
Color and Shape:
Solid
Molecular weight:
48-65 KDa (reducing condition)
Ref: TM-TMPJ-00212
| 1mg | 2,611.00 € | ||
| 10µg | 89.00 € | ||
| 50µg | 224.00 € | ||
| 500µg | 1,551.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.
Color and Shape:
Liquid
Molecular weight:
60-90 KDa (reducing condition)
Ref: TM-TMPJ-00613
| 1mg | 2,619.00 € | ||
| 10µg | 135.00 € | ||
| 50µg | 395.00 € | ||
| 500µg | 1,823.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, …
Formula:
C60H82N8O10
Purity:
97.76%
Color and Shape:
Solid
Molecular weight:
1075.36
Ref: TM-T14378L
| 2mg | 87.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 179.00 € | ||
| 1mL*10mM (DMSO) | 260.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MX69
CAS:1005264-47-0
MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.
Formula:
C27H26N2O4S
Purity:
97.27% - 99.57%
Color and Shape:
Solid
Molecular weight:
474.57
Ref: TM-T3653
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 225.00 € | ||
| 50mg | 363.00 € | ||
| 100mg | 541.00 € | ||
| 500mg | 1,170.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ASTX660
CAS:1799328-86-1
Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.
Formula:
C30H42FN5O3
Purity:
97.81% - 98.33%
Color and Shape:
Solid
Molecular weight:
539.68
Ref: TM-TQ0029
| 1mg | 83.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 214.00 € | ||
| 25mg | 427.00 € | ||
| 50mg | 631.00 € | ||
| 100mg | 897.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SM-164
CAS:957135-43-2
SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). …
Formula:
C62H84N14O6
Purity:
97.25% - 99.92%
Color and Shape:
Solid
Molecular weight:
1121.42
Ref: TM-T12932L
| 1mg | 115.00 € | ||
| 2mg | 168.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 413.00 € | ||
| 25mg | 670.00 € | ||
| 50mg | 925.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Birinapant
CAS:1260251-31-7
Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived …
Formula:
C42H56F2N8O6
Purity:
97.08% - ≥95%
Color and Shape:
Solid
Molecular weight:
806.94
Ref: TM-T6007
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 464.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BV6
CAS:1001600-56-1
BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) …
Formula:
C70H96N10O8
Purity:
98.00% - 99.89%
Color and Shape:
Solid
Molecular weight:
1205.57
Ref: TM-T6428
| 1mg | 52.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 792.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Xevinapant
CAS:1071992-99-8
Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, …
Formula:
C32H43N5O4
Purity:
98% - 99.56%
Color and Shape:
Solid
Molecular weight:
561.71
Ref: TM-T6763
| 1mg | 42.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 514.00 € | ||
| 100mg | 729.00 € | ||
| 200mg | 991.00 € | ||
| 500mg | 1,291.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LCL161
CAS:1005342-46-0
LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and …
Formula:
C26H33FN4O3S
Purity:
99.13% - 99.72%
Color and Shape:
Solid
Molecular weight:
500.63
Ref: TM-T2080
| 2mg | 68.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 445.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Isolinderalactone
CAS:957-66-4
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the …
Formula:
C15H16O3
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
244.29
Ref: TM-T8213
| 1mg | 87.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 302.00 € | ||
| 25mg | 506.00 € | ||
| 50mg | 724.00 € | ||
| 100mg | 985.00 € | ||
| 1mL*10mM (DMSO) | 171.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Embelin
CAS:550-24-3
Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked …
Formula:
C17H26O4
Purity:
97.07% - 99.88%
Color and Shape:
Solid
Molecular weight:
294.39
Ref: TM-T6485
| 10mg | 54.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 154.00 € | ||
| 100mg | 292.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Polygalacin D
CAS:66663-91-0
Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of …
Formula:
C57H92O27
Purity:
99.77% - ≥98%
Color and Shape:
Solid
Molecular weight:
1209.4
Ref: TM-TN2091
| 1mg | 119.00 € | ||
| 5mg | 340.00 € | ||
| 10mg | 507.00 € | ||
| 25mg | 820.00 € | ||
| 50mg | 1,101.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GDC-0152
CAS:873652-48-3
GDC-0152 is a potent inhibitor of IAPs.
Formula:
C25H34N6O3S
Purity:
97.18% - 99.32%
Color and Shape:
Solid
Molecular weight:
498.64
Ref: TM-T6299
| 1mg | 42.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 513.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CUDC-427
CAS:1446182-94-0
CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 …
Formula:
C29H36N6O4S
Purity:
98.99%
Color and Shape:
Solid
Molecular weight:
564.7
Ref: TM-T15018
| 1mg | 49.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 386.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Anticancer agent 128
CAS:2941243-62-3
Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 …
Formula:
C26H38N4O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
470.6
Ref: TM-T79248
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Feb 2025
Anticancer agent 127
CAS:2410953-19-2
Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, …
Formula:
C26H37FN4O6S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
552.66
Ref: TM-T79247
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Feb 2025
