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Kinesin

Kinesin

Kinesin inhibitors target kinesin motor proteins, which are responsible for transporting cellular cargo along microtubules and play a key role in cell division, particularly during mitosis. Kinesins are involved in the movement of chromosomes and other organelles during cell division. Inhibiting kinesins can disrupt these processes, leading to cell cycle arrest and potential cell death, making these inhibitors valuable in cancer research. At CymitQuimica, we offer a diverse range of high-quality kinesin inhibitors to support your research in cell biology, mitosis, and cancer therapy.

Found 87 products of "Kinesin"

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  • EMD534085
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    EMD534085

    CAS:
    EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
    Formula:C25H31F3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:476.53

    Ref: TM-TQ0314

  • HR22C16
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    HR22C16

    CAS:
    HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.
    Formula:C23H23N3O3
    Color and Shape:Solid
    Molecular weight:389.45

    Ref: TM-T24150

  • KIF18A-IN-3
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    KIF18A-IN-3

    CAS:
    KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.
    Formula:C28H38N4O5S2
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:574.76

    Ref: TM-T64068

  • Syntelin
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    Syntelin

    CAS:
    Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.
    Formula:C21H20N6O2S3
    Color and Shape:Solid
    Molecular weight:484.62

    Ref: TM-T71828

  • Mps1-IN-4
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    Mps1-IN-4

    CAS:
    Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.
    Formula:C26H31F3N6O2
    Color and Shape:Solid
    Molecular weight:516.56

    Ref: TM-T73229

  • Mps-BAY2b
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    Mps-BAY2b

    CAS:
    Mps-BAY2b is a novel MPS1 inhibitor.
    Formula:C20H23N5O
    Color and Shape:Solid
    Molecular weight:349.43

    Ref: TM-T28091

  • CFI-400936
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    CFI-400936

    CAS:
    CFI-400936: potent TTK inhibitor (IC50=3.6nM), potential anticancer, active in cell assays, selective vs. human kinases.
    Formula:C25H27N5O3S
    Color and Shape:Solid
    Molecular weight:477.58

    Ref: TM-T70940

  • Eg5 Inhibitor V, trans-24
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    Eg5 Inhibitor V, trans-24

    CAS:
    Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.
    Formula:C26H21N3O3
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:423.46

    Ref: TM-T11155

  • AM-5308
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    AM-5308

    CAS:
    AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.
    Formula:C26H35N5O5S
    Purity:98.06% - 99.58%
    Color and Shape:Solid
    Molecular weight:529.65

    Ref: TM-T63726

  • Litronesib Racemate
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    Litronesib Racemate

    CAS:
    Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.
    Formula:C23H37N5O4S2
    Color and Shape:Solid
    Molecular weight:511.7

    Ref: TM-T11859

  • PF-2771
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    PF-2771

    CAS:
    PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.
    Formula:C29H36ClN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:554.08

    Ref: TM-T12434

  • SR31527
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    SR31527

    CAS:
    SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.
    Formula:C15H14ClN3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.81

    Ref: TM-T28848

  • Kif15-IN-1
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    Kif15-IN-1

    CAS:
    Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.
    Formula:C20H22N4O5S
    Purity:99.39% - 99.39%
    Color and Shape:Solid
    Molecular weight:430.48

    Ref: TM-T15661

  • UMK57
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    UMK57

    CAS:
    UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,
    Formula:C17H17N3S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:295.4

    Ref: TM-T29059

  • TNH
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    TNH

    CAS:
    TNH, a dimeric compound, possesses the ability to penetrate living cells and facilitate the recruitment of proteins into cellular structures [1].
    Formula:C39H57ClN6O13
    Color and Shape:Solid
    Molecular weight:853.36

    Ref: TM-T80972

  • MC-Val-Cit-PAB-Ispinesib
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    MC-Val-Cit-PAB-Ispinesib

    CAS:
    MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].
    Formula:C59H71ClN10O10
    Color and Shape:Solid
    Molecular weight:1115.71

    Ref: TM-T84703

  • SB-743921 free base
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    SB-743921 free base

    CAS:
    SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).
    Formula:C31H33ClN2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:517.06

    Ref: TM-T28694

  • CCT251455
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    CCT251455

    CAS:
    <p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>
    Formula:C26H26ClN7O2
    Purity:99.1% - 99.1%
    Color and Shape:Solid
    Molecular weight:503.98

    Ref: TM-T14906

  • KIF18A-IN-7
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    KIF18A-IN-7

    CAS:
    KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent
    Formula:C27H35N3O5S2
    Color and Shape:Soild
    Molecular weight:545.71

    Ref: TM-T73050

  • Litronesib
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    Litronesib

    CAS:
    Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
    Formula:C23H37N5O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:511.7

    Ref: TM-T11859L

  • Kif15-IN-2
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    Kif15-IN-2

    CAS:
    Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.
    Formula:C20H20N6O4S
    Purity:98.17%
    Color and Shape:Solid
    Molecular weight:440.48

    Ref: TM-T11759

  • PVZB1194
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    PVZB1194

    CAS:
    PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through
    Formula:C13H9F4NO2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.28

    Ref: TM-T78125

  • NTRC 0066-0
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    NTRC 0066-0

    CAS:
    NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.
    Formula:C33H39N7O2
    Purity:98.30%
    Color and Shape:Solid
    Molecular weight:565.71

    Ref: TM-T28216

  • CCT-271850
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    CCT-271850

    CAS:
    CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.
    Formula:C24H29N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:431.53

    Ref: TM-T23865

  • KSP-IA
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    KSP-IA

    CAS:
    KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.
    Formula:C21H22F2N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:356.41

    Ref: TM-T24271

  • Luvixasertib hydrochloride
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    Luvixasertib hydrochloride

    CAS:
    CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].
    Formula:C28H31ClN6O3
    Color and Shape:Solid
    Molecular weight:535.04

    Ref: TM-T84711

  • Mps1-IN-10
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    Mps1-IN-10

    CAS:
    Mps1-IN-6 (Compound 9) is a highly effective Mps1 inhibitor with an IC50 value of 6.4 nM and exhibits significant anti-proliferation and anti-tumor effects on
    Formula:C24H27N7O2
    Color and Shape:Solid
    Molecular weight:445.52

    Ref: TM-T77779

  • CFI-402257
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    CFI-402257

    CAS:
    <p>CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.</p>
    Formula:C28H30N6O3
    Purity:96.66% - 99.51%
    Color and Shape:Solid
    Molecular weight:498.58

    Ref: TM-T22289

  • Mps1-IN-8
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    Mps1-IN-8

    CAS:
    Mps1-IN-8, a Mps1 inhibitor, can be utilized in the study of various tumors [1].
    Formula:C35H47N8O6P
    Color and Shape:Solid
    Molecular weight:706.77

    Ref: TM-T86927

  • NVP-BQS481
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    NVP-BQS481

    CAS:
    NVP-BQS481 (Compound 1) is a selective inhibitor of spindle motor protein 5 (Eg5), with an IC50 of less than 0.5 nM. It demonstrates significant anti-mitotic and anti-tumor activities, exhibiting an IC50 of 0.09 nM against SK-OV-3ip cells. NVP-BQS481 is suitable for use as a cytotoxic payload in the synthesis of antibody-drug conjugates (ADCs).
    Formula:C27H33F3N4O2
    Color and Shape:Solid
    Molecular weight:502.57

    Ref: TM-T212559

  • Mitotic kinesin-IN-1 hydrochloride
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    Mitotic kinesin-IN-1 hydrochloride

    CAS:
    Mitotic kinesin-IN-1 hydrochloride (Example 80) is an inhibitor of mitotic kinesin, which suppresses cell proliferation by hindering mitosis. This compound is applicable in research related to cancer, cardiac hypertrophy, immune and inflammatory diseases, and fungal infections.
    Formula:C22H26ClF2N3OS
    Color and Shape:Solid
    Molecular weight:453.98

    Ref: TM-T212561

  • Kolavenic acid analog
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    Kolavenic acid analog

    CAS:
    KAA, an anticancer compound, inhibits centrosome clustering and targets HSET+ yeast and cancer cells.
    Formula:C25H38O4
    Color and Shape:Solid
    Molecular weight:402.57

    Ref: TM-T61970

  • RMS-07
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    RMS-07

    CAS:
    RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.
    Formula:C35H40N8O2
    Color and Shape:Solid
    Molecular weight:604.74

    Ref: TM-T73483

  • MKLP2-IN-1
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    MKLP2-IN-1

    CAS:
    <p>MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.</p>
    Formula:C23H19BrFN3O2
    Color and Shape:Solid
    Molecular weight:468.318

    Ref: TM-T205538

  • AM-9022
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    AM-9022

    CAS:
    AM-9022 is a potent and selective KIF18A inhibitor, orally active and suitable for cancer research [1].
    Formula:C27H36F2N6O4S
    Color and Shape:Solid
    Molecular weight:578.67

    Ref: TM-T85640

  • Terpendole E
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    Terpendole E

    CAS:
    Terpendole E is an atypical L5 site inhibitor.
    Formula:C28H39NO3
    Color and Shape:Solid
    Molecular weight:437.61

    Ref: TM-T70289

  • EX05
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    EX05

    CAS:
    EX05, an effective KIF18A inhibitor, exhibits an IC50 of 8.2 nM and holds potential for cancer research applications.
    Formula:C26H30F2N4O5S
    Color and Shape:Solid
    Molecular weight:548.60

    Ref: TM-T88621