Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
Found 268 products of "Integrin"
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huATN-658
huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting the urokinase-type plasminogen activator receptor (uPAR). It effectively disrupts the interaction between uPAR and integrins, thereby inhibiting tumor cell proliferation, invasion, and migration. huATN-658 shows potential for research in breast cancer, particularly in cases of triple-negative breast cancer.Color and Shape:Odour LiquidICAM-1988
CAS:ICAM-1988 is a LFA-1 antagonist.Formula:C22H22Cl2N4O6SColor and Shape:SolidMolecular weight:541.4SAN-300
SAN-300 is a human-derived IgG1 monoclonal antibody (mAb) that targets ITGA1/VLA-1. It is utilized in the research of rheumatoid arthritis.Color and Shape:Odour LiquidLDV-FITC TFA
LDV-FITC TFA is a fluorescent peptide, specifically an FITC-conjugated LDV peptide. This compound binds to the α4β1 integrin with high affinity, displaying a Kd of 0.3 nM in the presence of Mn2+ and 12 nM in its absence, when binding to U937 cells. LDV-FITC TFA is useful for assessing α4β1 integrin affinity.Formula:C69H81N11O17S·xC2HF3O2R-BC154 acetate
R-BC154 acetate: selective α9β1 antagonist, high-affinity integrin probe for α9β1/α4β1 activity study.Formula:C56H65N9O14S3Color and Shape:SolidMolecular weight:1184.36EMD527040
CAS:EMD527040 is a potent αvβ6 antagonist with antifibrotic effects, used in carcinoma and liver fibrosis research.Formula:C29H32Cl2N4O5Color and Shape:SolidMolecular weight:587.5PLN-1474
CAS:PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Formula:C24H37N3O4Purity:99.92%Color and Shape:SoildMolecular weight:431.57Ref: TM-T60101
1mg50.00€5mg105.00€10mg170.00€25mg289.00€50mg416.00€100mg580.00€1mL*10mM (DMSO)117.00€Nelvutamig
CAS:Nelvutamig is a humanized immunoglobulin antibody (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3) designed to target ENPP3/CD203c and CD3E. The corresponding isotype control is Human immunoglobulin (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3).Color and Shape:LiquidGanodermaones B
Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .Formula:C21H26O5Color and Shape:SolidMolecular weight:358.43KGDS
CAS:KGDS is a synthetic peptide that targets the integrin GPIIb-IIIa on the membrane of activated human platelets, with the amino acid sequence Lys-Gly-Asp-Ser [1].Formula:C15H27N5O8Color and Shape:SolidMolecular weight:405.4Lys-Gln-Ala-Gly-Asp-Val
CAS:KQAGDV is a fibrinogen γ-chain cell adhesion peptide, targeting α2bβ3 integrin, and binds SMCs.Formula:C25H44N8O10Color and Shape:SolidMolecular weight:616.66Fibrinogen Binding Inhibitor Peptide
CAS:Synthetic dodecapeptide mimics human fibrinogen g-chain, inhibits platelet receptor (residues 400-411).Formula:C50H80N18O16Purity:98%Color and Shape:SolidMolecular weight:1189.28GRGDSPK TFA
GRGDSPK TFA is an RGD peptide, competitive inhibitor of integrin-fibronectin, used to research integrins in bone dynamics.Formula:C30H50F3N11O13Color and Shape:SolidMolecular weight:829.78Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Purity:>95%Color and Shape:LiquidMolecular weight:146.1 kDaIntegrin Binding Peptide
CAS:Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.Formula:C42H63N15O16SColor and Shape:SolidMolecular weight:1066.12MS133
MS133 is a human bispecific antibody targeting CD133/PROM1 and CD3E. It is used in the study of colon cancer.Color and Shape:Odour LiquidRTDLDSLRTYTL
CAS:RTDLDSLRTYTL is a high-affinity and specific inhibitor of Alpha (v) beta (6) integrin (avb6). By binding to the avb6 integrin, this peptide sequence activates T cell cytotoxicity and cytokine production, such as interferon-γ. Through the design of chimeric T cell antigen receptors (CAR), RTDLDSLRTYTL enables T cells to be redirected, allowing them to specifically recognize and attack tumor cells. It is used in research for cancer immunotherapy and the development of targeted drugs.Formula:C62H104N18O22Color and Shape:SolidMolecular weight:1453.60HSDVHK-NH2 TFA
HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [Formula:C32H49F3N12O11Color and Shape:SolidMolecular weight:834.8A20FMDV2
CAS:A20FMDV2 is a highly selective αvβ6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for αvβ6 compared to other RGD-directed integrins like αvβ3, αvβ5, and α5β1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of αvβ6 integrin-positive tumors.Formula:C93H163N31O28Color and Shape:SolidMolecular weight:2163.48GSK 3008348 hydrochloride
CAS:GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.Formula:C29H37N5O2xHClPurity:99.54%Color and Shape:SolidMolecular weight:0
