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Integrin

Integrin

Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.

Found 224 products of "Integrin"

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  • A-205804

    CAS:
    <p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>
    Formula:C15H12N2OS2
    Purity:98.07% - 98.52%
    Color and Shape:Solid
    Molecular weight:300.4
  • Cyclo(-RGDfK)

    CAS:
    <p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>
    Formula:C27H41N9O7
    Purity:95.29% - >99.99%
    Color and Shape:Solid
    Molecular weight:603.67
  • PND-1186

    CAS:
    <p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>
    Formula:C25H26F3N5O3
    Purity:99.14% - 99.75%
    Color and Shape:Solid
    Molecular weight:501.5
  • GLPG0187

    CAS:
    <p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>
    Formula:C29H37N7O5S
    Purity:99.4% - 99.70%
    Color and Shape:Solid
    Molecular weight:595.71
  • OSU-T315

    CAS:
    <p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>
    Formula:C30H30F3N5O
    Purity:98.69%
    Color and Shape:Solid
    Molecular weight:533.59
  • Arginine-glycine-aspartic acid

    CAS:
    <p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>
    Formula:C12H22N6O6
    Purity:99.11%
    Color and Shape:Solid
    Molecular weight:346.34
  • Cyclo(RADfK)

    CAS:
    <p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>
    Formula:C28H43N9O7
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:617.7
  • Cyclo(-RGDfK) TFA

    CAS:
    <p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>
    Formula:C29H42F3N9O9
    Purity:98.99% - 99.54%
    Color and Shape:Solid
    Molecular weight:717.69
  • CWHM-12

    CAS:
    <p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>
    Formula:C26H32BrN5O6
    Purity:98.05% - 99.83%
    Color and Shape:Solid
    Molecular weight:590.47
  • H-Gly-Arg-Gly-Asp-Asn-Pro-OH

    CAS:
    <p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>
    Formula:C23H38N10O10
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:614.61
  • iRGD peptide

    CAS:
    <p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>
    Formula:C35H57N13O14S2
    Purity:98.77%
    Color and Shape:Solid
    Molecular weight:948.04
  • Leukadherin-1

    CAS:
    <p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>
    Formula:C22H15NO4S2
    Purity:98.49% - 98.93%
    Color and Shape:Solid
    Molecular weight:421.49
  • Pyrintegrin

    CAS:
    <p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>
    Formula:C23H25N5O3S
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:451.54
  • Orbofiban

    CAS:
    <p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>
    Formula:C17H23N5O4
    Color and Shape:Solid
    Molecular weight:361.4
  • Cucurbitacin B

    CAS:
    <p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>
    Formula:C32H46O8
    Purity:97.1% - 99.33%
    Color and Shape:Solid
    Molecular weight:558.7
  • ILK-IN-2

    CAS:
    <p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>
    Formula:C30H30F3N5O
    Purity:99.30%
    Color and Shape:Solid
    Molecular weight:533.59
  • A-286982

    CAS:
    <p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>
    Formula:C24H27N3O4S
    Purity:97.81%
    Color and Shape:Solid
    Molecular weight:453.55
  • Arg-Gly-Asp TFA (99896-85-2(free base))


    <p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>
    Formula:C14H23F3N6O8
    Purity:99.2% - ≥98%
    Color and Shape:Solid
    Molecular weight:460.36
  • roxifiban

    CAS:
    <p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>
    Formula:C21H29N5O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:447.48
  • LXW7

    CAS:
    <p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>
    Formula:C29H48N12O12S2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:820.89