Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
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GSK 3008348 hydrochloride
CAS:1629249-40-6
GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.
Formula:
C29H37N5O2xHCl
Purity:
98%
Color and Shape:
Solid
Molecular weight:
0
Ref: TM-T15583
| 1mg | 94.00 € | ||
| 5mg | 225.00 € | ||
| 10mg | 316.00 € | ||
| 25mg | 527.00 € | ||
| 50mg | 753.00 € | ||
| 100mg | 1,055.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves …
Formula:
C184H284N52O57S8·3C2H4O2
Purity:
99.51%
Color and Shape:
Liquid
Molecular weight:
4573.21
Ref: TM-T78219
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Egaptivon pegol
CAS:934868-74-3
Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T78666
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
BT100
BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, …
Purity:
98%
Ref: TM-T79188
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Volociximab
CAS:558480-40-3
Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor …
Purity:
95%
Color and Shape:
Liquid
Ref: TM-T9901A-008
| 1mg | 335.00 € | ||
| 5mg | 991.00 € | ||
| 10mg | 1,633.00 € | ||
| 25mg | 2,406.00 € | ||
| 50mg | 3,266.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
RO0270608
CAS:220846-33-3
RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory …
Formula:
C24H19Cl3N2O4
Purity:
98.55%
Color and Shape:
Liquid
Molecular weight:
505.78
Ref: TM-T36716
| 1mg | 113.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 446.00 € | ||
| 25mg | 778.00 € | ||
| 50mg | 1,077.00 € | ||
| 100mg | 1,449.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Bexotegrast
CAS:2376257-44-0
Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study …
Formula:
C27H36N6O3
Purity:
99.53%
Color and Shape:
Liquid
Molecular weight:
492.61
Ref: TM-T39933
| 1mg | 122.00 € | ||
| 5mg | 431.00 € | ||
| 10mg | 744.00 € | ||
| 25mg | 1,292.00 € | ||
| 50mg | 2,192.00 € | ||
| 100mg | 3,600.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cilengitide TFA
CAS:199807-35-7
Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.
Formula:
C29H41F3N8O9
Color and Shape:
Solid
Molecular weight:
702.68
Ref: TM-T6806
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Irigenin
CAS:548-76-5
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin …
Formula:
C18H16O8
Purity:
99.71% - 99.85%
Color and Shape:
Solid
Molecular weight:
360.31
Ref: TM-T3862
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 180.00 € | ||
| 100mg | 271.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Cyclo(RGDyK) trifluoroacetate
CAS:250612-42-1
Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
Formula:
C31H43F6N9O12
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
847.72
Ref: TM-T6813
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 454.00 € | ||
| 100mg | 661.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:114681-65-1
RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.
Formula:
C23H38N10O10
Purity:
100%
Color and Shape:
Solid
Molecular weight:
614.61
Ref: TM-T7570
| 1mg | 36.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 332.00 € | ||
| 100mg | 489.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Leukadherin-1
CAS:344897-95-6
Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.
Formula:
C22H15NO4S2
Purity:
98% - 98.49%
Color and Shape:
Solid
Molecular weight:
421.49
Ref: TM-T3638
| 5mg | 46.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 116.00 € | ||
| 50mg | 200.00 € | ||
| 100mg | 324.00 € | ||
| 200mg | 485.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CWHM-12
CAS:1564286-55-0
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).
Formula:
C26H32BrN5O6
Purity:
98.05% - 98.5%
Color and Shape:
Solid
Molecular weight:
590.47
Ref: TM-TQ0250
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 538.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Cyclo(RADfK)
CAS:756500-23-9
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's …
Formula:
C28H43N9O7
Purity:
100%
Color and Shape:
Solid
Molecular weight:
617.7
Ref: TM-TP1330
| 1mg | 94.00 € | ||
| 5mg | 220.00 € | ||
| 10mg | 324.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 782.00 € | ||
| 100mg | 1,054.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BIO-1211
CAS:187735-94-0
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 …
Formula:
C36H48N6O9
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
708.8
Ref: TM-T21868
| 1mg | 110.00 € | ||
| 2mg | 163.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 435.00 € | ||
| 25mg | 702.00 € | ||
| 50mg | 926.00 € | ||
| 100mg | 1,295.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Cyclo(-RGDfK)
CAS:161552-03-0
Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of …
Formula:
C27H41N9O7
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
603.67
Ref: TM-T6812
| 1mg | 46.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 272.00 € | ||
| 50mg | 378.00 € | ||
| 100mg | 530.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PND-1186
CAS:1061353-68-1
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
Formula:
C25H26F3N5O3
Purity:
99.14% - ≥98%
Color and Shape:
Solid
Molecular weight:
501.5
Ref: TM-T1950
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 199.00 € | ||
| 100mg | 289.00 € | ||
| 500mg | 696.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
OSU-T315
CAS:2070015-22-2
OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.
Formula:
C30H30F3N5O
Purity:
98.03%
Color and Shape:
Solid
Molecular weight:
533.59
Ref: TM-T5485
| 1mg | 96.00 € | ||
| 2mg | 143.00 € | ||
| 5mg | 232.00 € | ||
| 10mg | 373.00 € | ||
| 25mg | 640.00 € | ||
| 50mg | 909.00 € | ||
| 100mg | 1,210.00 € | ||
| 500mg | 2,452.00 € | ||
| 1mL*10mM (DMSO) | 303.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tirofiban hydrochloride monohydrate
CAS:150915-40-5
Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.
Formula:
C22H39ClN2O6S
Purity:
95.83% - 99.94%
Color and Shape:
White Solid
Molecular weight:
495.07
Ref: TM-T2537
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 116.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 303.00 € | ||
| 500mg | 723.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
A-205804
CAS:251992-66-2
A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) …
Formula:
C15H12N2OS2
Purity:
98.07% - 98.52%
Color and Shape:
Solid
Molecular weight:
300.4
Ref: TM-T2254
| 2mg | 48.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 268.00 € | ||
| 100mg | 528.00 € | ||
| 500mg | 1,142.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
